NR-283 week 1 (Latest Update 2026 /
2027) Pathophysiology Questions and
Verified Answers 100% Correct -
Chamberlain
Which kind of screening can determine the paternity of a child?
Pre-pregnancy
Prenatal
Neonatal
Non-pregnancy related - correct answer Prenatal
Which genetic testing puts the mother and fetus at risk for infection and miscarriage? -
correct answer amniocentesis and chorionic villus sampling
How long after a newborn has arrived, can you test for metabolic disorders? - correct
answer 48 hours a heel stick can be used
Which of the following are common physical characteristics of Down syndrome? Select
all that apply.
Congenital heart defect
,Widely spaced big toes
Limited intellectual development
Large protruding tongue
Cleft lip and palate - correct answer Congenital heart defect
Widely spaced big toes
Large protruding tongue
Cleft lip and palate
Down syndrome is a chromosomal genetic disorder that occurs in individuals with an
extra copy of a chromosome from the ___ pair. - correct answer 21st
*Trisomy 21
With Trisomy 21, the extra chromosome is present in ___ - correct answer all cells in
the person's body.
For those living with Down Syndrome, when does translocation occur? - correct
answer when the extra chromosome 21 attaches, or translocates, to a different
chromosome.
Where does Mosaic Down Syndrome result from? - correct answer results from a
combination of cells with three copies of chromosome 21 and the others with only two
,Explain the pathophysiology of Down Syndrome - correct answer Regular Trisomy 21
happens when instead of two chromosome 21's, they have three. With translocation,
that third chromosome breaks off and attaches itself to another chromosome. During
Mosaic they have a mixture of normal cells with 46 chromosomes and some with (47)
trisomy (that one extra chromosome)
Which type of Down syndrome presents with fewer characteristics of Down syndrome?
Trisomy 21
Translocation
Mosaic - correct answer Mosaic
When discussing the pathophysiology of Down syndrome. In which type do we see a
genetic alteration in all cells? SATA
Trisomy 21
Translocation
Mosaic - correct answer Trisomy 21
Translocation
, Standard screening tests for Down syndrome include: - correct answer alpha fetal
protein analysis
nuchal (neck) translucency (NT) testing.
Diagnostic tests used for Down syndrome? - correct answer -Chorionic villus
sampling (CVS) examines genetic material from the placenta.
-Amniocentesis examines genetic material from the amniotic fluid.
-Percutaneous umbilical blood sampling (PUBS) examines fetal blood from the
umbilical cord.
Place the sources of the genetic alteration that causes Down syndrome in order,
starting with the one found in most people living with Down syndrome.
After fertilization
Biological father's sperm
Biological mother's ovum (egg) - correct answer Biological mother's ovum (egg)
Biological father's sperm
After fertilization
A young adult stepped on a rusty nail last evening. After removing the nail and
cleaning the wound, they applied a bandage and went to sleep. This morning the skin
around the bandage is red, warm, painful, and oozing a thick, yellow drainage.
2027) Pathophysiology Questions and
Verified Answers 100% Correct -
Chamberlain
Which kind of screening can determine the paternity of a child?
Pre-pregnancy
Prenatal
Neonatal
Non-pregnancy related - correct answer Prenatal
Which genetic testing puts the mother and fetus at risk for infection and miscarriage? -
correct answer amniocentesis and chorionic villus sampling
How long after a newborn has arrived, can you test for metabolic disorders? - correct
answer 48 hours a heel stick can be used
Which of the following are common physical characteristics of Down syndrome? Select
all that apply.
Congenital heart defect
,Widely spaced big toes
Limited intellectual development
Large protruding tongue
Cleft lip and palate - correct answer Congenital heart defect
Widely spaced big toes
Large protruding tongue
Cleft lip and palate
Down syndrome is a chromosomal genetic disorder that occurs in individuals with an
extra copy of a chromosome from the ___ pair. - correct answer 21st
*Trisomy 21
With Trisomy 21, the extra chromosome is present in ___ - correct answer all cells in
the person's body.
For those living with Down Syndrome, when does translocation occur? - correct
answer when the extra chromosome 21 attaches, or translocates, to a different
chromosome.
Where does Mosaic Down Syndrome result from? - correct answer results from a
combination of cells with three copies of chromosome 21 and the others with only two
,Explain the pathophysiology of Down Syndrome - correct answer Regular Trisomy 21
happens when instead of two chromosome 21's, they have three. With translocation,
that third chromosome breaks off and attaches itself to another chromosome. During
Mosaic they have a mixture of normal cells with 46 chromosomes and some with (47)
trisomy (that one extra chromosome)
Which type of Down syndrome presents with fewer characteristics of Down syndrome?
Trisomy 21
Translocation
Mosaic - correct answer Mosaic
When discussing the pathophysiology of Down syndrome. In which type do we see a
genetic alteration in all cells? SATA
Trisomy 21
Translocation
Mosaic - correct answer Trisomy 21
Translocation
, Standard screening tests for Down syndrome include: - correct answer alpha fetal
protein analysis
nuchal (neck) translucency (NT) testing.
Diagnostic tests used for Down syndrome? - correct answer -Chorionic villus
sampling (CVS) examines genetic material from the placenta.
-Amniocentesis examines genetic material from the amniotic fluid.
-Percutaneous umbilical blood sampling (PUBS) examines fetal blood from the
umbilical cord.
Place the sources of the genetic alteration that causes Down syndrome in order,
starting with the one found in most people living with Down syndrome.
After fertilization
Biological father's sperm
Biological mother's ovum (egg) - correct answer Biological mother's ovum (egg)
Biological father's sperm
After fertilization
A young adult stepped on a rusty nail last evening. After removing the nail and
cleaning the wound, they applied a bandage and went to sleep. This morning the skin
around the bandage is red, warm, painful, and oozing a thick, yellow drainage.
