TEST BANK
Fundamentals of Molecular Virology
Christopher D. Richardson
3rd Edition
Chapters 1-37 (Questions with Verified Answers)
PR
O
FD
O
C
1|P age
, Chapter Number: 01
Question type: Multiple Choice
1) Which of the following terms describes the protein shell that surrounds the viral genome?
a) capsid
b) envelope
c) matrix
d) virion
e) capsomere Correct Answer: a
PR
2) Which of the following would not be a nucleic acid form found in a viral genome?
a) dsDNA
b) ssDNA
O
c) dsRNA
d) ssRNA
FD
e) an RNA:DNA hybrid Correct Answer: e
3) Which of the following is an enzyme that most RNA viruses encode in their genome?
O
a) DNA-dependent-RNA-polymerase
b) RNA-dependent-RNA-polymerase
C
c) DNA-dependent-DNA-polymerase
d) DNA-dependent-RNA-polymerase
e) RNA-dependent-protein-synthetase Correct Answer: b
4) Viruses play a major role in the ecology of the ocean by doing which of the following?
a) By infecting photosynthetic bacteria and increasing their growth.
2|P age
,b) By infecting harmful bacteria found in the ocean and limiting their growth.
c) By killing off fish and preventing them from becoming too plentiful.
d) By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.
e) All of the above statements are correct.
Correct Answer: d
5) If you wanted to show that an infectious agent is a virus, what experiment could you do?
a) Show that the agent can be seen under a light microscope.
b) Show that agent contains a lipid membrane.
PR
c) Show that the agent can form single colonies on an agar plate.
d) Show that the agent can be diluted and can still cause disease in an animal.
e) Show that the agent can pass through a porcelain filter and is still infectious.
O
Correct Answer: e
FD
6) What does the word “virus” mean in Latin?
a) infectious agent
b) liquid
O
c) poison
d) death
C
e) disease Correct Answer: c
7) The word “phage” is a shortened version of the name of a virus that can infect which type of
organism?
a) bacterial cell
b) human cell
c) eukaryotic cell
3|P age
, d) plant cell
e) inset cell Correct Answer: a
8) The study of which group of viruses led to the discovery of cellular genes that can promoter cancer in
animal cells?
a) papillomaviruses
b) retroviruses
c) adneoviruses
d) polyomaviruses
PR
e) picornaviruses Correct Answer: b
9) When doing a plaque assay with human or animal cells, a layer of nutrient media mixed with agar is
put on top of the cells after they have been infected with the diluted virus. What is the major purpose of
O
this agar layer?
a) It helps to feed the cells as they grow.
FD
b) It promotes the replication of the virus.
c) It makes the infected cells easier to visualize.
d) It limits the movement of virus particles.
O
e) All of the above are correct.
Correct Answer: d
C
10) To start an experiment, you do an infection by putting 0.5 ml of a virus stock that has a titer of 6 x
107 pfu/ml onto a plate of animal cells that contains 5 x 106 cells. What is the multiplicity of infection for
this experiment?
a) 12
b) 6
c) 5
d) 3
4|P age
Fundamentals of Molecular Virology
Christopher D. Richardson
3rd Edition
Chapters 1-37 (Questions with Verified Answers)
PR
O
FD
O
C
1|P age
, Chapter Number: 01
Question type: Multiple Choice
1) Which of the following terms describes the protein shell that surrounds the viral genome?
a) capsid
b) envelope
c) matrix
d) virion
e) capsomere Correct Answer: a
PR
2) Which of the following would not be a nucleic acid form found in a viral genome?
a) dsDNA
b) ssDNA
O
c) dsRNA
d) ssRNA
FD
e) an RNA:DNA hybrid Correct Answer: e
3) Which of the following is an enzyme that most RNA viruses encode in their genome?
O
a) DNA-dependent-RNA-polymerase
b) RNA-dependent-RNA-polymerase
C
c) DNA-dependent-DNA-polymerase
d) DNA-dependent-RNA-polymerase
e) RNA-dependent-protein-synthetase Correct Answer: b
4) Viruses play a major role in the ecology of the ocean by doing which of the following?
a) By infecting photosynthetic bacteria and increasing their growth.
2|P age
,b) By infecting harmful bacteria found in the ocean and limiting their growth.
c) By killing off fish and preventing them from becoming too plentiful.
d) By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.
e) All of the above statements are correct.
Correct Answer: d
5) If you wanted to show that an infectious agent is a virus, what experiment could you do?
a) Show that the agent can be seen under a light microscope.
b) Show that agent contains a lipid membrane.
PR
c) Show that the agent can form single colonies on an agar plate.
d) Show that the agent can be diluted and can still cause disease in an animal.
e) Show that the agent can pass through a porcelain filter and is still infectious.
O
Correct Answer: e
FD
6) What does the word “virus” mean in Latin?
a) infectious agent
b) liquid
O
c) poison
d) death
C
e) disease Correct Answer: c
7) The word “phage” is a shortened version of the name of a virus that can infect which type of
organism?
a) bacterial cell
b) human cell
c) eukaryotic cell
3|P age
, d) plant cell
e) inset cell Correct Answer: a
8) The study of which group of viruses led to the discovery of cellular genes that can promoter cancer in
animal cells?
a) papillomaviruses
b) retroviruses
c) adneoviruses
d) polyomaviruses
PR
e) picornaviruses Correct Answer: b
9) When doing a plaque assay with human or animal cells, a layer of nutrient media mixed with agar is
put on top of the cells after they have been infected with the diluted virus. What is the major purpose of
O
this agar layer?
a) It helps to feed the cells as they grow.
FD
b) It promotes the replication of the virus.
c) It makes the infected cells easier to visualize.
d) It limits the movement of virus particles.
O
e) All of the above are correct.
Correct Answer: d
C
10) To start an experiment, you do an infection by putting 0.5 ml of a virus stock that has a titer of 6 x
107 pfu/ml onto a plate of animal cells that contains 5 x 106 cells. What is the multiplicity of infection for
this experiment?
a) 12
b) 6
c) 5
d) 3
4|P age
