WGU D115 ADVANCED
PATHOPHYSIOLOGY FOR THE ADVANCED
PRACTICE NURSE EXAM | 2025/2026
UPDATE | ACTUAL QUESTIONS AND
ANSWERS | WITH VERIFIED SOLUTIONS
Type 1 Diabetes Mellitus - ANSWERS-Type 1 DM is associated with
beta cell destruction leading to absolute insulin deficiency resulting in
significant hyperglycemia and potential for ketoacidosis.
Type 2 Diabetes Mellitus Risk Factors - ANSWERS-Major risk factors
are heredity and obesity.
Endometrial Cancer Risk Factor - ANSWERS-Oral contraceptives have
been shown to reduce the incidence of endometrial cancer.
Mixed Precocious Puberty - ANSWERS-Mixed precocious puberty cases
the child to develop some secondary characteristics of the opposite
sex, such as the feminization of a boy.
Delayed Puberty Cause - ANSWERS-In 95% of cases, delayed puberty
is physiologic in nature.
,Priapism Association - ANSWERS-Priapism has been associated with
the abuse of certain substances.
Priapism - ANSWERS-Prolonged penile erection, often idiopathic.
Cocaine - ANSWERS-Substance associated with priapism.
Ovulation - ANSWERS-Triggered by a sudden increase of LH.
Follicular cyst - ANSWERS-Develops when no dominant follicle
matures.
Benign ovarian cyst - ANSWERS-Functional cyst from incomplete
follicle maturation.
Genetic counseling - ANSWERS-Advisory service for individuals at
genetic risk.
Maternal age - ANSWERS-Common reason for seeking genetic
counseling.
Glasgow Coma Scale (GCS) - ANSWERS-The GCS is scored between 3
and 15, 3 being the worst and 15 the best.
Severe TBI GCS Score - ANSWERS-A GCS score of 3-8 describes a
severe TBI.
,Obsessions - ANSWERS-Obsessions are recurrent and persistent
thoughts, impulses, or images that cause distressing emotions such as
anxiety or disgust.
Generalized Anxiety Disorder (GAD) Characteristics - ANSWERS-
Impaired concentration and irritability are major characteristics of
GAD.
Schizophrenia Symptoms - ANSWERS-The characteristics of
schizophrenia are paranoia, delusions, tangential thoughts,
suspiciousness, disorganized behavior, and hallucinations.
Acute Otitis Media - ANSWERS-The classic presentation of otitis media
is otalgia, muffled hearing, popping sensation, and a recent history of
a cold or flare up of allergic rhinitis.
Peritonsillar Abscess - ANSWERS-Peritonsillar abscess is
characterized by severe sore throat, pain or difficulty swallowing, jaw
muscle spasms, and a hot potato voice.
Graves' Disease - ANSWERS-Graves' disease, an autoimmune condition
also known as 'diffuse toxic goiter' is the most common cause of
hyperthyroidism in this age group.
Insulin Resistance Finding - ANSWERS-Triglycerides > 150mg/dL is
associated with increasing insulin resistance.
, Postprandial Glucose Level Influencer - ANSWERS-Carbohydrate is a
macronutrient with the greatest impact on the postprandial glucose
levels.
Amniocentesis - ANSWERS-Procedure to perform genetic studies on
fetus.
Turner Syndrome - ANSWERS-Condition with monosomy X in affected
cells.
Cri du chat syndrome - ANSWERS-Genetic disorder with distinctive cat-
like cry.
Adaptive immunity - ANSWERS-Immune response mediated by T and B
cells.
Minimally conscious state - ANSWERS-Patient shows limited but
definite responses.
Acute respiratory distress syndrome (ARDS) - ANSWERS-Severe lung
inflammation with bilateral infiltrates.
Capillary hydrostatic pressure - ANSWERS-Increased pressure causing
pulmonary edema.
PATHOPHYSIOLOGY FOR THE ADVANCED
PRACTICE NURSE EXAM | 2025/2026
UPDATE | ACTUAL QUESTIONS AND
ANSWERS | WITH VERIFIED SOLUTIONS
Type 1 Diabetes Mellitus - ANSWERS-Type 1 DM is associated with
beta cell destruction leading to absolute insulin deficiency resulting in
significant hyperglycemia and potential for ketoacidosis.
Type 2 Diabetes Mellitus Risk Factors - ANSWERS-Major risk factors
are heredity and obesity.
Endometrial Cancer Risk Factor - ANSWERS-Oral contraceptives have
been shown to reduce the incidence of endometrial cancer.
Mixed Precocious Puberty - ANSWERS-Mixed precocious puberty cases
the child to develop some secondary characteristics of the opposite
sex, such as the feminization of a boy.
Delayed Puberty Cause - ANSWERS-In 95% of cases, delayed puberty
is physiologic in nature.
,Priapism Association - ANSWERS-Priapism has been associated with
the abuse of certain substances.
Priapism - ANSWERS-Prolonged penile erection, often idiopathic.
Cocaine - ANSWERS-Substance associated with priapism.
Ovulation - ANSWERS-Triggered by a sudden increase of LH.
Follicular cyst - ANSWERS-Develops when no dominant follicle
matures.
Benign ovarian cyst - ANSWERS-Functional cyst from incomplete
follicle maturation.
Genetic counseling - ANSWERS-Advisory service for individuals at
genetic risk.
Maternal age - ANSWERS-Common reason for seeking genetic
counseling.
Glasgow Coma Scale (GCS) - ANSWERS-The GCS is scored between 3
and 15, 3 being the worst and 15 the best.
Severe TBI GCS Score - ANSWERS-A GCS score of 3-8 describes a
severe TBI.
,Obsessions - ANSWERS-Obsessions are recurrent and persistent
thoughts, impulses, or images that cause distressing emotions such as
anxiety or disgust.
Generalized Anxiety Disorder (GAD) Characteristics - ANSWERS-
Impaired concentration and irritability are major characteristics of
GAD.
Schizophrenia Symptoms - ANSWERS-The characteristics of
schizophrenia are paranoia, delusions, tangential thoughts,
suspiciousness, disorganized behavior, and hallucinations.
Acute Otitis Media - ANSWERS-The classic presentation of otitis media
is otalgia, muffled hearing, popping sensation, and a recent history of
a cold or flare up of allergic rhinitis.
Peritonsillar Abscess - ANSWERS-Peritonsillar abscess is
characterized by severe sore throat, pain or difficulty swallowing, jaw
muscle spasms, and a hot potato voice.
Graves' Disease - ANSWERS-Graves' disease, an autoimmune condition
also known as 'diffuse toxic goiter' is the most common cause of
hyperthyroidism in this age group.
Insulin Resistance Finding - ANSWERS-Triglycerides > 150mg/dL is
associated with increasing insulin resistance.
, Postprandial Glucose Level Influencer - ANSWERS-Carbohydrate is a
macronutrient with the greatest impact on the postprandial glucose
levels.
Amniocentesis - ANSWERS-Procedure to perform genetic studies on
fetus.
Turner Syndrome - ANSWERS-Condition with monosomy X in affected
cells.
Cri du chat syndrome - ANSWERS-Genetic disorder with distinctive cat-
like cry.
Adaptive immunity - ANSWERS-Immune response mediated by T and B
cells.
Minimally conscious state - ANSWERS-Patient shows limited but
definite responses.
Acute respiratory distress syndrome (ARDS) - ANSWERS-Severe lung
inflammation with bilateral infiltrates.
Capillary hydrostatic pressure - ANSWERS-Increased pressure causing
pulmonary edema.
