GALEN PHARMACOLOGY EXAM 1 QUESTIONS AND ANSWERS
What is Pharmacokinetics - CORRECT ANSWER✅✅what the body does to the drug
What is Pharmacodynamics - CORRECT ANSWER✅✅what the drug does to the body
What phase is Pharmacokinetics - CORRECT ANSWER✅✅Absorption phase
Where does absorption of a drug take place - CORRECT ANSWER✅✅Small intestine
What affects absorption time - CORRECT ANSWER✅✅-Pill type
-stomach contents
-blood circulation
-pain, stress, anxiety
-route of administration
Contraindicators for medications - CORRECT ANSWER✅✅Grapefruit juice and antacids
what is disintegration - CORRECT ANSWER✅✅breakdown of oral drug into smaller particles
What is dissolution - CORRECT ANSWER✅✅Process of combining small drug particles with liquid to
form a solution
What is drug absorption - CORRECT ANSWER✅✅Drug movement from GI tract into bloodstream
happens in small intestine
What is bioavailability - CORRECT ANSWER✅✅What is left of drug after swallowing.
PO meds will never have 100% bioavailability
, Factors affecting Bioavailability - CORRECT ANSWER✅✅-Absorption
-first pass metabolism
-Drug form
-route of admin
-gastric mucous % motility
-changes in liver metabolism
-Administration w/ food and other drugs
What is first pass effect - CORRECT ANSWER✅✅drugs absorbed from the GI tract enter the portal vein
and pass through the liver before entering circulation.
PO meds only
Characteristics of ADHD - CORRECT ANSWER✅✅Inattentiveness, inability to concentrate, restlessness,
hyperactivity, inability to complete tasks, impulsivity
Characteristics of narcolepsy - CORRECT ANSWER✅✅recurrent attacks of drowsiness and sleep during
daytime
unable to control sleep
falling asleep while driving, talking, eating, standing
Where does drug metablosim occur - CORRECT ANSWER✅✅In the the liver
What is drug metabolism - CORRECT ANSWER✅✅process of body chemically changing drug into a form
to be excreted
What is the half-life of a drug? - CORRECT ANSWER✅✅the time it takes for the drug in body to be
reduced by half
What is a loading dose - CORRECT ANSWER✅✅Large initial dose of medication followed by small
maintence dose
What is Pharmacokinetics - CORRECT ANSWER✅✅what the body does to the drug
What is Pharmacodynamics - CORRECT ANSWER✅✅what the drug does to the body
What phase is Pharmacokinetics - CORRECT ANSWER✅✅Absorption phase
Where does absorption of a drug take place - CORRECT ANSWER✅✅Small intestine
What affects absorption time - CORRECT ANSWER✅✅-Pill type
-stomach contents
-blood circulation
-pain, stress, anxiety
-route of administration
Contraindicators for medications - CORRECT ANSWER✅✅Grapefruit juice and antacids
what is disintegration - CORRECT ANSWER✅✅breakdown of oral drug into smaller particles
What is dissolution - CORRECT ANSWER✅✅Process of combining small drug particles with liquid to
form a solution
What is drug absorption - CORRECT ANSWER✅✅Drug movement from GI tract into bloodstream
happens in small intestine
What is bioavailability - CORRECT ANSWER✅✅What is left of drug after swallowing.
PO meds will never have 100% bioavailability
, Factors affecting Bioavailability - CORRECT ANSWER✅✅-Absorption
-first pass metabolism
-Drug form
-route of admin
-gastric mucous % motility
-changes in liver metabolism
-Administration w/ food and other drugs
What is first pass effect - CORRECT ANSWER✅✅drugs absorbed from the GI tract enter the portal vein
and pass through the liver before entering circulation.
PO meds only
Characteristics of ADHD - CORRECT ANSWER✅✅Inattentiveness, inability to concentrate, restlessness,
hyperactivity, inability to complete tasks, impulsivity
Characteristics of narcolepsy - CORRECT ANSWER✅✅recurrent attacks of drowsiness and sleep during
daytime
unable to control sleep
falling asleep while driving, talking, eating, standing
Where does drug metablosim occur - CORRECT ANSWER✅✅In the the liver
What is drug metabolism - CORRECT ANSWER✅✅process of body chemically changing drug into a form
to be excreted
What is the half-life of a drug? - CORRECT ANSWER✅✅the time it takes for the drug in body to be
reduced by half
What is a loading dose - CORRECT ANSWER✅✅Large initial dose of medication followed by small
maintence dose
