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Question 1
Roux-en-Y gastric bypass surgery (RYGB) accounts for about 80% of bariatric procedures in the US and is usually done
laparoscopically. During RYGB, a small part of the proximal stomach is detached from the rest of the stomach, creating a
stomach pouch of < 30 mL. Which of the following preexisting conditions has been shown to go into remission in up to
62% of patients 6 yr after RYGB?
a. Hypertension
b. Diabetes
c. Obesity
d. Obstructive Sleep Apnea
Correct Answer
Answer: B: Diabetes is particularly likely to remit. Remission rates are up to 62% after 6 yr. A and D: Other comorbid
conditions that tend to abate or resolve after bariatric surgery include cardiovascular risk factors (eg, dyslipidemia,
hypertension [A], diabetes), cardiovascular disorders, obstructive sleep apnea (D), osteoarthritis, and depression. C: For
RYGB, weight loss is 50 to 65% after 2 yr; weight loss after RYGB is maintained for up to 10 yr. All-cause mortality
decreases by 25%, primarily because cardiovascular and cancer mortality is reduced.
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,Question 2
Which of the following procedures is being used increasingly in the US as definitive treatment for severe obesity (eg, in
patients with a body mass index [BMI] > 60)?
a. Sleeve Gastrectomy
b. Roux-en Y Gastric Bypass
c. Adjustable Gastric Banding
d. Vertical Banded Gastroplasty
Correct Answer
Answer: A: Sleeve gastrectomy; because this procedure causes substantial and sustained weight loss, it is being used
increasingly in the US as definitive treatment for severe obesity. Part of the stomach is removed, creating a tubular
stomach passage. The procedure does not involve anatomic changes to the small intestine. B: Nonetheless, Roux-en-Y
gastric bypass surgery accounts for about 80% of bariatric procedures in the US. C: Use of adjustable gastric banding has
dramatically decreased in the US. D: Vertical banded gastroplasty is no longer commonly done because complication
rates are high and the resulting weight loss is insufficient.
Question 3
Contraindications to bariatric surgery include which of the following?
a. Body mass index (BMI) < 30 kg/m2
b. Current drug or alcohol abuse
c. Obstructive sleep apnea
d. High-risk lipid profile
Correct Answer
Answer: B: Current drug or alcohol abuse. A: The use of bariatric surgery is controversial in patients with a BMI < 30. C
and D: To qualify for bariatric surgery, patients should have a BMI of > 40 or a BMI of > 35 plus a serious complication
(eg, diabetes, hypertension, obstructive sleep apnea [C], high-risk lipid profile [D]).
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,Question 4
Bariatric Surgery Key Points
Correct Answer
Consider weight loss surgery if patients are motivated, have not succeeded using nonsurgical treatments, and have a BMI
of > 40 kg/m2 or a BMI of > 35 kg/m2 plus a serious complication (eg, diabetes, hypertension, obstructive sleep apnea,
high-risk lipid profile) or a BMI of 30 to 34.9 with type 2 diabetes and inadequate glycemic control despite optimal
lifestyle and medical therapy.
Weight loss surgery is contraindicated if patients have an uncontrolled psychiatric disorder (eg, major depression), drug
or alcohol abuse, cancer that is not in remission, or another life-threatening disorder or if they cannot comply with
nutritional requirements (including life-long vitamin replacement when indicated).
The most common procedures are sleeve gastrectomy and Roux-en-Y gastric bypass; use of adjustable gastric banding
has decreased dramatically in the US.
Monitor patients regularly after surgery for maintenance of weight loss, resolution of weight-related comorbid disorders,
and complications of surgery (eg, nutritional deficiencies, metabolic bone disease, gout, cholelithiasis, nephrolithiasis,
depression, alcohol abuse).
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, Question 5
Which of the following increases the risk of cardiovascular disorders in patients with obesity?
a. Osteoporosis
b. Excess abdominal fat
c. Psychological disorders
d. Gastric Ulcer
Correct Answer
Answer: B: Excess abdominal fat. Complications, including coronary artery disease, are more likely in patients with fat that
is concentrated abdominally. Choices A, C, and D do not increase the risk of cardiovascular disorders in patients with
obesity.
Question 6
What is the role of ghrelin in food intake-regulating pathways?
a. It increases food intake.
b. It decreases food intake.
c. Level decreases when weight is lost.
d. It integrates energy balance signals.
Correct Answer
Answer: A: Ghrelin, secreted primarily by the stomach, increases food intake. B, C, and D: Other hormones and regulatory
substances have these effects.
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