GRADED A+
✔✔Which of the following animals used in laboratory animal research would be covered
by the Animal Welfare Act - ✔✔Guinea pigs, rabbits, hamsters, ferrets, wild mice,
horses, gerbils, goats, sheep
✔✔The chapter lists some of the requirements in the Animal Welfare Act and the
Animal Welfare Regulations if covered species are used. List five requirements -
✔✔register with the USDA, appoint IACUC, provide training for animal users, maintain
animal records, provide adequate vet care
✔✔The appropriate use of analgesics in postsurgical animals would apply to which of
the 3 Rs principles? - ✔✔Refinement
✔✔According to the Guide and PHS Policy, what document must institutions comply
with when animals are euthanized? - ✔✔AVMA Guidelines for Euthanasia
✔✔List two common alternatives to using animals for research studies - ✔✔Cell
cultures, mathematical models
✔✔Beyond food, water, shelter, and healthcare requirements, the AWA and AWRs
require that dogs have the opportunity for ______ and NHPS have ______ enrichment -
✔✔exercise; psychological
✔✔List three differences between the PHS Policy and the Animal Welfare act - ✔✔PHS
policy covers all vertebrates used in research, PHS policy has some administrative
differences in its IACUC requirements, PHS policy requires an Occ Health and Safety
program
✔✔Function of the IACUC - ✔✔An institutional body that oversees and evaluates an
animal care and use program
✔✔Function of Quality Assurance Unit - ✔✔An institution unit that ensures compliance
with the GLP
✔✔Function of Animal & Plant Health Inspection Service - ✔✔The body that administers
and enforces the Animal Welfare Regulations
✔✔Function of Association for the Assessment and Accreditation of Laboratory Animal
Care International - ✔✔A nonprofit organization that accredits laboratory animal
research programs
,✔✔Function of Office of Laboratory Animal Welfare - ✔✔The body that administers and
enforces the PHS policy
✔✔Using 100 mice in a research study instead of 150 would be an example of which of
the 3 Rs? - ✔✔Reduction
✔✔Some institutions may have to comply with PHS Policy but not animal welfare act.
What are the factors that help determine which regulations are relevant to a particular
research study - ✔✔The species of animals used the funding sources
✔✔Purpose of disaster plan - ✔✔Provides steps for disaster preparedness and
response
✔✔Purpose of emergency contact list - ✔✔Identifies whom to call if an emergency
occurs
✔✔Purpose of disaster drill - ✔✔Measures the effectiveness of institution-wide
emergency systems
✔✔Purpose of post-incident discussion - ✔✔Identifies ways to improve the disaster plan
and emergency procedures
✔✔Purpose of security plan - ✔✔Describes ways to prevent and address security
breaches
✔✔List two ways to maintain security when visitors come to the facility - ✔✔Don't admit
anyone unless authorized; contact supervisor if someone approaches you and tell them
immediately
✔✔List three steps to prevent security breaches - ✔✔never prop open any doors
leading to the outside; do not let people "piggyback"; display badge; don't let anyone
borrow your badge
✔✔What type of device identifies individuals using distinct characteristics such as
fingerprints or eye structure - ✔✔Biometric scanners
✔✔If you are present in the facility when a major disaster or accident occurs, your
actions will be very important. What should be your first priority? - ✔✔Protect human life
by calling out to others and evacuating if necessary, call the appropriate first
responders, call your supervisor or other senior staff
✔✔What document should be posted throughout the facility, and is consulted and used
when there is an emergency - ✔✔Contact list
, ✔✔List four questions you should be ready to answer when you report a disaster or
incident at your facility - ✔✔Where did the incident occur; which areas are affected; is
there a power loss; is everybody accounted for
✔✔What is the goal of an occupational health and safety program? - ✔✔To minimize
the risk of occupational injuries for all employees
✔✔Name the federal agency that enforces rules and standards for workplace safety -
✔✔Occupational Safety and Health Administration
✔✔Should a pregnant employee be assigned to work with cats? - ✔✔No, cats carry the
microbes that cause toxoplasmosis, which can harm the fetus
✔✔List three things that determine the type of PPE needed when working in the facility -
✔✔animal species, the hazards present, the potential for exposure to infectious or
chemical agents
✔✔List three important factors for personal protection against radiation - ✔✔time,
shielding, distance
✔✔Virus carried by Old World macaque monkeys - ✔✔B virus
✔✔Disease that can be transmitted from animals to humans - ✔✔Zoonoses
✔✔Emission of energy rays through the air and other matter - ✔✔Radioactivity
✔✔Parasite that can be transmitted through cat feces - ✔✔Toxoplasma gondii
✔✔A unit that measures loudness - ✔✔decibel
✔✔Provides information on toxicity and potential side effects, and describes
recommended treatment for exposures - ✔✔Material safety data sheets
✔✔Designing a workplace to minimize fatigue, discomfort or injury - ✔✔Ergonomics
✔✔Respirator mask that protects against airborne particles - ✔✔N95
✔✔Hazard of assisting the PI with obtaining x-rays of mice - ✔✔Radiation exposure
✔✔Hazard of using descaler to clean dropoing pans - ✔✔Burns from chemicals
✔✔Hazard of feeding barking dogs - ✔✔Hearing problems