2026 FULL QUESTIONS AND CORRECT
ANSWERS
◉ Second Line Treatments for alcohol use disorder (according to study
guide but not dynamed). Answer: Disulfuram and Bupropion (not FDA
approved for ETOH but second line according to study guide)
◉ Second Line Treatment for alcohol use disorder (according to
Dynamed). Answer: Disulfuram
◉ Other off label medications for alcohol use disorder according to
Dynamed. Answer: Topiramate, gabapentin, baclofen
◉ Other off label medications for alcohol use disorder according to
Stahl's. Answer: Topiramate, ondansetron
◉ MOA of Naltrexone. Answer: Opioid Receptor Antagonist
◉ MOA of Acamprosate. Answer: - weak GABAa agonist
- weak NMDA antagonist
, (does not prevent withdrawal symptoms)
◉ MOA of Disulfuram. Answer: inhibits enzyme (aldehyde
dehydrogenase) in the liver
◉ Bupropions role in alcohol use disorder. Answer: Can diminish
cravings for etoh, treat underlying anxiety/depression
◉ Safety Risk associated with bupropion and etoh. Answer: bupropion
increases the risk of seizures in those going through etoh withdrawal
◉ s/s ETOH intoxication. Answer: impaired fine motor control,
impaired judgement and coordination, ataxic gait, poor balance, lethargy,
difficulty sitting upright, difficulty with memory and sitting upright,
N/V, coma in levels 300mg/dL and over with respiratory depression and
death possible
◉ S/S of etoh withdrawal. Answer: Mild: insomnia, irritability, hand
tremor
Moderate: autonomic hyperactivity (diaphoresis, tachycardia, HTN),
fever
Severe: seizures (12-48 hours post consumption), hallucinations,
Delirium Tremens