AAMC MCAT UPDATED TESTED QUESTIONS AND
ANSWERS GUARANTEE A+
✔✔If the combined mass of the TPMT substrate and cofactor was determined before
the enzymatically catalyzed reaction and then compared to the combined mass of the
product and the cofactor after the reaction, the net change in molecular weight will be: -
✔✔Passage says that TPMT is an enzyme (methyltransferase)
can also think about the conservation of mass
balance equation on products and reactants
✔✔The structure of Compound 2 is shown.
Compound 2
What structural feature(s) is(are) most important to the functioning of this compound as
described in the passage? - ✔✔- Compound 2 helped extract the receptor
- Receptor is MPR (progesterone) steroid is hydrophobic so probably has to do
someting with that
✔✔Which experimental evidence suggests that the purified hMPRα obtained by the
researchers was in its native state? - ✔✔Dude. Just stop. C is the answer. It literally
says.
A. The tags that were used for extraction could still intefere with the protein's native
function/binding
✔✔A major obstacle to obtaining useful energy from a nuclear fusion reactor is
containment of the fuel at the very high temperatures required for fusion. The reason
such high temperatures are required is to: - ✔✔A MAKES NO SENSE
WHY WOULD YOU USE HIGH TEMPS TO ELIMINATE THE NULEAR FORCE
charge is always conserved no matter the carge
C- the higher density the material, the closer the nucleic are to each oter
✔✔Enantiomers can exhibit a difference in which chemical or physical property? - ✔✔-
Enantiomers retain most properties (density, boiling point, IR spect)
- The strong nuclear force is what holds a nucleus together, fusion would want a strong
nuclear force to hold the. protons together
✔✔Which classification of amino acids applies to the Trp residues after photochemical
modification by CCl3CO2H? - ✔✔Carboxylic is an acid
it is not asking about trp in general but rather the residues
✔✔Based on the passage, what most likely causes W96 to be accessible to CHCl3 at
75°C?
A.
Peptide bonds are broken, releasing W96.
, B.
Reduction of disulfide bonds occurs.
C.
The protein unfolds and exposes W96 to the buffer.
D.
CHCl3 extracts W96 from the protein interior. - ✔✔Passage says: temperature which
fully denatures carbonic anhydrase but leaves its primary structure intact
primary structure= amino acids
Peptide bonds are not broke
✔✔What is the name of the ionic compound used to make Buffer B?
A.
Ammonium formate
B.
Ammonium carbonate
C.
Ammonium bicarbonate
D.
Ammonium acetate - ✔✔formate: hco2
carbonate: Hco3-
bicarbonate: hco3-
acetate: ch3cooh
✔✔Which chromatographic technique would most likely separate a mixture of native
carbonic anhydrase from carbonic anhydrase photochemically modified by CCl3CO2H?
- ✔✔Passage says: Native carbonic anhydrase also has a net charge of -2.9 at pH 8.0.
The photochemical adds carboxylic acids which are negatively charged
✔✔Pv=nrt - ✔✔Helps you look at the relationship between everything
4 mols of CO react to give you 2 mol of product
n is halved that mean pressure is halved bc direct relationship
0.5*1
✔✔In which phase(s) will the MCS precursor be predominantly found after the
extraction step? - ✔✔Passage MCS is a lipophillic precursor (it loves lipids) so it is not
water soluble
✔✔When the covalent attachment to alliinase is broken, PLP is still held rigidly in the
active site by a salt bridge and a π-stacking interaction. These interactions are most
likely provided by the side chains of which amino acids? - ✔✔Can eliminate B and D
because they do not include pi stacking (tyrosine pi stacks)
Now between Asp and Arg. Use passage info
Alliinase is a pyridoxal phosphate (PLP, vitamin B6) dependent enzyme. PLP is a planar
molecule with a 6-membered ring, a hydroxyl group, an aldehyde group, and a
ANSWERS GUARANTEE A+
✔✔If the combined mass of the TPMT substrate and cofactor was determined before
the enzymatically catalyzed reaction and then compared to the combined mass of the
product and the cofactor after the reaction, the net change in molecular weight will be: -
✔✔Passage says that TPMT is an enzyme (methyltransferase)
can also think about the conservation of mass
balance equation on products and reactants
✔✔The structure of Compound 2 is shown.
Compound 2
What structural feature(s) is(are) most important to the functioning of this compound as
described in the passage? - ✔✔- Compound 2 helped extract the receptor
- Receptor is MPR (progesterone) steroid is hydrophobic so probably has to do
someting with that
✔✔Which experimental evidence suggests that the purified hMPRα obtained by the
researchers was in its native state? - ✔✔Dude. Just stop. C is the answer. It literally
says.
A. The tags that were used for extraction could still intefere with the protein's native
function/binding
✔✔A major obstacle to obtaining useful energy from a nuclear fusion reactor is
containment of the fuel at the very high temperatures required for fusion. The reason
such high temperatures are required is to: - ✔✔A MAKES NO SENSE
WHY WOULD YOU USE HIGH TEMPS TO ELIMINATE THE NULEAR FORCE
charge is always conserved no matter the carge
C- the higher density the material, the closer the nucleic are to each oter
✔✔Enantiomers can exhibit a difference in which chemical or physical property? - ✔✔-
Enantiomers retain most properties (density, boiling point, IR spect)
- The strong nuclear force is what holds a nucleus together, fusion would want a strong
nuclear force to hold the. protons together
✔✔Which classification of amino acids applies to the Trp residues after photochemical
modification by CCl3CO2H? - ✔✔Carboxylic is an acid
it is not asking about trp in general but rather the residues
✔✔Based on the passage, what most likely causes W96 to be accessible to CHCl3 at
75°C?
A.
Peptide bonds are broken, releasing W96.
, B.
Reduction of disulfide bonds occurs.
C.
The protein unfolds and exposes W96 to the buffer.
D.
CHCl3 extracts W96 from the protein interior. - ✔✔Passage says: temperature which
fully denatures carbonic anhydrase but leaves its primary structure intact
primary structure= amino acids
Peptide bonds are not broke
✔✔What is the name of the ionic compound used to make Buffer B?
A.
Ammonium formate
B.
Ammonium carbonate
C.
Ammonium bicarbonate
D.
Ammonium acetate - ✔✔formate: hco2
carbonate: Hco3-
bicarbonate: hco3-
acetate: ch3cooh
✔✔Which chromatographic technique would most likely separate a mixture of native
carbonic anhydrase from carbonic anhydrase photochemically modified by CCl3CO2H?
- ✔✔Passage says: Native carbonic anhydrase also has a net charge of -2.9 at pH 8.0.
The photochemical adds carboxylic acids which are negatively charged
✔✔Pv=nrt - ✔✔Helps you look at the relationship between everything
4 mols of CO react to give you 2 mol of product
n is halved that mean pressure is halved bc direct relationship
0.5*1
✔✔In which phase(s) will the MCS precursor be predominantly found after the
extraction step? - ✔✔Passage MCS is a lipophillic precursor (it loves lipids) so it is not
water soluble
✔✔When the covalent attachment to alliinase is broken, PLP is still held rigidly in the
active site by a salt bridge and a π-stacking interaction. These interactions are most
likely provided by the side chains of which amino acids? - ✔✔Can eliminate B and D
because they do not include pi stacking (tyrosine pi stacks)
Now between Asp and Arg. Use passage info
Alliinase is a pyridoxal phosphate (PLP, vitamin B6) dependent enzyme. PLP is a planar
molecule with a 6-membered ring, a hydroxyl group, an aldehyde group, and a
