BIOL 351/ BIOL351 Module 5: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
The craniofacial skeletal tissues are primarily derived from a combination of ___________ and
_________?
Cranial neural crest, mesoderm
Which of the following embryonic structures gives rise to Meckel's cartilage, the precursor of the
mandible?
Pharyngeal Arch 1
Which of the following are necessary for cranial neural crest cell multipotency and survival?
FGF8
A farmer has several ewes that gave birth to lambs with cyclopia and midline craniofacial
defects. This is most likely due to which of the following?
Exposure to agents that antagonize Shh signaling
In the early embryo what signals must occur together in the splanchnic mesoderm for
cardiogenic mesoderm to be specified?
DKK, Crescent, Cereberus, FGF8, and BMP
, BIOL 351/ BIOL351 Module 5: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
Which of the following represents an important outcome of looping?
Establishment of left-right asymmetry
During heart development which of the following represent the correct temporal events in
morphogenesis?
A. Formation of heart primordia, formation of the linear heart tube, looping, and septation
Defects in endocardial cushions are often associated with craniofacial defects suggesting a
common link to neural crest cells.
True
The neural crest is derived from _______. An important step in neural crest induction is
activation of the __________ promoter. Fill in the blanks with best answer.
ectoderm, β-catenin
In the diagrams below, which one illustrates the most likely outcome of a selective defect in
cardiac neural crest development?
D
Which of the following genes is essential for melanocyte development?
KIT
, BIOL 351/ BIOL351 Module 5: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
Choose the best answer from the dropdown menus. Melanocytes derive from ["endoderm",
"neural crest", "mesoderm", "hypoderm"] and migrate ["rostrally", "ventrally", "dorsolaterally",
"caudally"].
neural crest, dorsolaterally
Vasculogenesis is an _____________ process that makes new blood vessels, and ________ trims
and remodels the vasculature.
embryonic, angiogenesis
Hemangioblasts are specified by ______________ in the ________________.
FGF2 signaling, splanchnic mesoderm
If you made a knockout of EphB4, how would this affect development of the circulatory system?
Arteries and veins would not connect properly
Differentiation of a blood vessel into an artery or a vein is regulated by which of the following?
Notch signaling
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
The craniofacial skeletal tissues are primarily derived from a combination of ___________ and
_________?
Cranial neural crest, mesoderm
Which of the following embryonic structures gives rise to Meckel's cartilage, the precursor of the
mandible?
Pharyngeal Arch 1
Which of the following are necessary for cranial neural crest cell multipotency and survival?
FGF8
A farmer has several ewes that gave birth to lambs with cyclopia and midline craniofacial
defects. This is most likely due to which of the following?
Exposure to agents that antagonize Shh signaling
In the early embryo what signals must occur together in the splanchnic mesoderm for
cardiogenic mesoderm to be specified?
DKK, Crescent, Cereberus, FGF8, and BMP
, BIOL 351/ BIOL351 Module 5: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
Which of the following represents an important outcome of looping?
Establishment of left-right asymmetry
During heart development which of the following represent the correct temporal events in
morphogenesis?
A. Formation of heart primordia, formation of the linear heart tube, looping, and septation
Defects in endocardial cushions are often associated with craniofacial defects suggesting a
common link to neural crest cells.
True
The neural crest is derived from _______. An important step in neural crest induction is
activation of the __________ promoter. Fill in the blanks with best answer.
ectoderm, β-catenin
In the diagrams below, which one illustrates the most likely outcome of a selective defect in
cardiac neural crest development?
D
Which of the following genes is essential for melanocyte development?
KIT
, BIOL 351/ BIOL351 Module 5: (Latest
2026/ 2027 Update) 100% Verified
Questions & correct Answers | Grade A
Choose the best answer from the dropdown menus. Melanocytes derive from ["endoderm",
"neural crest", "mesoderm", "hypoderm"] and migrate ["rostrally", "ventrally", "dorsolaterally",
"caudally"].
neural crest, dorsolaterally
Vasculogenesis is an _____________ process that makes new blood vessels, and ________ trims
and remodels the vasculature.
embryonic, angiogenesis
Hemangioblasts are specified by ______________ in the ________________.
FGF2 signaling, splanchnic mesoderm
If you made a knockout of EphB4, how would this affect development of the circulatory system?
Arteries and veins would not connect properly
Differentiation of a blood vessel into an artery or a vein is regulated by which of the following?
Notch signaling
