TEST BANK FOR Cellular and Molecular Immunology 10th Edition by Abul K. Abbas, Andrew H. Lichtman ISBN: 978-0323757485 COMPLETE GUIDE ALL CHAPTERS COVERED WITH RATIONALES 100% VERIFIED A+ GRADE ASSURED!!!!!NEW LATEST UPDATE!!!!!

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Cellular and Molecular Immunology
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Abul Abbas, Andrew Lichtman, and Shiv Pillai
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10th Edition
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,Table of Contents
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Chapter 01 Properties and Overview of Immune Responses
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Chapter 02 Cells and Tissues of the Immune System
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Chapter 03 Leukocyte Circulation and Migration Into Tissues
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Chapter 04 Innate Immunity
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Chapter 05 Antibodies and Antigens
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Chapter 06 Antigen Presentation to T Lymphocytes and the Functions of Major
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Histocompatibility Complex Molecules dt dt 20
Chapter 07 Immune Receptors and Signal Transduction
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Chapter 08 Lymphocyte Development and Antigen Receptor Gene Rearrangement
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Chapter 09 Activation of T Lymphocytes
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Chapter 10 Differentiation and Functions of CD4+ Effector T Cells
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Chapter 11 Differentiation and Functions of CD8+ Effector T Cells
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Chapter 12 B Cell Activation and Antibody Production
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Chapter 13 Effector Mechanisms of Humoral Immunity
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Chapter 14 Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
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Chapter 15 Immunologic Tolerance and Autoimmunity
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Chapter 16 Immunity to Microbes
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Chapter 17 Transplantation Immunology
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Chapter 18 Tumor Immunology
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Chapter 19 Hypersensitivity Disorders
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Chapter 20 Allergy
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Chapter 21 Primary and Acquired Immunodeficiencies
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,Chapter 01: Properties and Overview of Immune Responses
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Abbas, Lichtman, and Pillai: Cellular and Molecular Immunology, 10th Edition
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MULTIPLE CHOICE dt




1. The principal function of the immune system is:
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a. Defense against cancer dt dt



b. Repair of injured tissues dt dt dt



c. Defense against microbial infections dt dt dt



d. Prevention of inflammatory diseases dt dt dt



e. Protection against environmental toxins dt dt dt




ANS: C d t



The immune system has evolved in the setting of selective pressures imposed by microbial inf
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ections. Although immune responses to cancer may occur, the concept that “immunosurveill
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ance” against cancer is a principal function of the immune system is controversial. Repair of i
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njured tissues may be a secondary consequence of the immune responses and inflammation.
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Although the immune system has regulatory features that are needed to prevent excessive inf
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lammation, prevention of inflammatory diseases is not a primary function. The immune syste
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m can protect against microbial toxins, but it generally does not offer protection against toxins
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of nonbiologic origin.
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2. Which of the following infectious diseases was prevented by the first successful v
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accination?
a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
ANS: C d t



In 1798, Edward Jenner reported the first intentional successful vaccination, which was agai
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nst smallpox in a boy, using material from the cowpox pustules of a milkmaid. In 1980, smallp
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ox was reported to be eradicated worldwide by a vaccination program. Effective vaccines ag
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ainst tetanus toxin, rubella virus, and poliovirus were developed in the 20th century and are
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widely used. There is no effective vaccine against Mycobacterium tuberculosis.
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3. Which of the following is a unique property of the adaptive immune system?
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a. Highly diverse repertoire of specificities for antigens dt dt dt dt dt dt



b. Self-nonself discrimination dt



c. Recognition of microbial structures by both cell-associated and soluble receptors dt dt dt dt dt dt dt dt dt



d. Protection against viral infections dt dt dt



e. Responses that have the same kinetics and magnitude on repeated exposure to the sa dt dt dt dt dt dt dt dt dt dt dt dt dt



me microbe dt




ANS: A d t

, Highly diverse repertoires of specificities for antigens are found only in T and B lymphocyte
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s, which are the central cellular components of the adaptive immune system. Both the innate a
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nd the adaptive immune systems use cell-
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associated and soluble receptors to recognize microbes, display some degree of self-
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nonself discrimination, and protect against viruses. On repeated exposure to the same microb
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e, the adaptive immune response becomes more rapid and of greater magnitude; this is the ma
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nifestation of memory. dt dt




4. Antibodies and T lymphocytes are the respective mediators of which two types of i
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mmunity?
a. Innate and adaptive dt dt



b. Passive and active dt dt



c. Specific and nonspecific dt dt



d. Humoral and cell-mediated dt dt



e. Adult and neonatal dt dt




ANS: D d t



Both B and T lymphocytes are principal components of adaptive immunity. B lymphocytes pr
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oduce antibodies, which are the recognition and effector molecules of humoral immune respo
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nses to extracellular pathogens. T cells recognize and promote eradication of intracellular path
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ogens in cell- dt dt



mediated immunity. Passive and active immunity both can be mediated by either B or T lymph
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ocytes. Specific immunity is another term for adaptive immunity. Both B and T lymphocytes p
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articipate in adult adaptive immunity but are still developing in the neonatal period.
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5. The two major functional classes of effector T lymphocytes are:
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a. Helper T lymphocytes and cytotoxic T lymphocytes dt dt dt dt dt dt




b. Natural killer cells and cytoWtoWxW
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c. Memory T cells and effector T cells dt dt dt dt dt dt



d. Helper cells and antigen-presenting cells dt dt dt dt



e. Cytotoxic T lymphocytes and target cells dt dt dt dt dt




ANS: A d t



T cells can be classified into effector subsets that perform different effector functions. Most eff
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ector T cells are either helper T lymphocytes, which enhance the responses of other immune
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cells, including phagocytes and B cells, to infections, or cytotoxic T lymphocytes, which dire
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ctly kill infected cells. Natural killer cells are not T lymphocytes.
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Antigen-presenting cells usually are not T cells. Memory T cells are not effector T cells. dt dt dt dt dt dt dt dt dt dt dt dt dt dt




6. Which of the following cell types is required for all adaptive humoral immune responses?
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a. Natural killer cells dt dt



b. Dendritic cells dt



c. Cytolytic T lymphocytes dt dt



d. B lymphocytes dt



e. Helper T lymphocytes dt dt




ANS: D d t



Humoral immune responses are antibody- dt dt dt dt



mediated immune responses, and all antibodies are made by B lymphocytes and no other ce
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ll type.
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