EKU PMHNP NSC 830 EXAM QUESTIONS WITH
CORRECT ANSWERS
Pharmacology |- |CORRECT |ANSWER✔✔-Study |of |drugs |and |drug |actions
Pharmacodynamics |- |CORRECT |ANSWER✔✔-what |the |drug |does |in |the |body-or |to |the |target |
cell
Receptors |- |CORRECT |ANSWER✔✔-Protiens |located |on |the |surgaces |of |the |cell |membranes |or |
w/in |cells. |"the |lock"
When |drug |molecules |bind |with |receptors |molecules |- |CORRECT |ANSWER✔✔-the |resulting |
drug-receptor |complex |initiates |a |physio-chemical |reaction |that |stimulates |or |inhibits |it's |
normal |cell |function
Agonist |- |CORRECT |ANSWER✔✔-drugs |that |produce |effects |similar |to |those |produced |by |
naturally |occurring |hormones, |neurotransmitters, |and |other |natural |substances.
Antagonist |- |CORRECT |ANSWER✔✔-drugs |that |inhibit |cell |fx |by |occupying |receptor |sites
Therapeutic |Index |- |CORRECT |ANSWER✔✔-The |relationship |between |a |drugs |desired |
therapeutic |effects |and |its |adverse |effects
Wide |therapeutic |index |- |CORRECT |ANSWER✔✔-drug |is |safe, |close |monitoring |not |required
, Narrow |therapeutic |index |- |CORRECT |ANSWER✔✔-Amount |of |drug |required |for |therapeutic |
effect |is |not |much |different |that |the |amount |of |drug |producing |a |toxic |effect. |< |2. |Close |
monitoring |needed.
Minimal |effective |Concentration |- |CORRECT |ANSWER✔✔-The |minimal |blood |level |at |which |
the |drug |exerts |the |desired |effect
Area |under |the |curve |- |CORRECT |ANSWER✔✔-plot |of |the |plasma |concentration |vs. |time |after |
a |single |dose |of |drug |is |administered
T-max |- |CORRECT |ANSWER✔✔-time |to |maximum |(peak) |drug |level |after |a |drug |is |
administered
C-max |- |CORRECT |ANSWER✔✔-maximum |(peak) |concentration |of |a |drug |after |it |is |
administered
First-Pass |effect |- |CORRECT |ANSWER✔✔-Some |drugs, |when |passing |from |the |intestines |to |the |
liver, |get |metabolized |with |only |part |of |drug |dose |reaching |systemic |circulation |for |distribution
Bio-availability |- |CORRECT |ANSWER✔✔-% |of |drug |that |reaches |systemic |circulation |after |an |
administered |dose. |Used |to |determine |drug |dose.
Potency |- |CORRECT |ANSWER✔✔-a |relative |measure |that |compares |the |doses |of |2 |different |
drugs |that |are |required |to |achieve |the |same |effect
Half-Life |- |CORRECT |ANSWER✔✔-the |time |required |for |the |serum |concentration |of |a |drug |to |
decrease |by |50%
Efficacy |- |CORRECT |ANSWER✔✔-The |maximum |effect |a |drug |can |achieve
CORRECT ANSWERS
Pharmacology |- |CORRECT |ANSWER✔✔-Study |of |drugs |and |drug |actions
Pharmacodynamics |- |CORRECT |ANSWER✔✔-what |the |drug |does |in |the |body-or |to |the |target |
cell
Receptors |- |CORRECT |ANSWER✔✔-Protiens |located |on |the |surgaces |of |the |cell |membranes |or |
w/in |cells. |"the |lock"
When |drug |molecules |bind |with |receptors |molecules |- |CORRECT |ANSWER✔✔-the |resulting |
drug-receptor |complex |initiates |a |physio-chemical |reaction |that |stimulates |or |inhibits |it's |
normal |cell |function
Agonist |- |CORRECT |ANSWER✔✔-drugs |that |produce |effects |similar |to |those |produced |by |
naturally |occurring |hormones, |neurotransmitters, |and |other |natural |substances.
Antagonist |- |CORRECT |ANSWER✔✔-drugs |that |inhibit |cell |fx |by |occupying |receptor |sites
Therapeutic |Index |- |CORRECT |ANSWER✔✔-The |relationship |between |a |drugs |desired |
therapeutic |effects |and |its |adverse |effects
Wide |therapeutic |index |- |CORRECT |ANSWER✔✔-drug |is |safe, |close |monitoring |not |required
, Narrow |therapeutic |index |- |CORRECT |ANSWER✔✔-Amount |of |drug |required |for |therapeutic |
effect |is |not |much |different |that |the |amount |of |drug |producing |a |toxic |effect. |< |2. |Close |
monitoring |needed.
Minimal |effective |Concentration |- |CORRECT |ANSWER✔✔-The |minimal |blood |level |at |which |
the |drug |exerts |the |desired |effect
Area |under |the |curve |- |CORRECT |ANSWER✔✔-plot |of |the |plasma |concentration |vs. |time |after |
a |single |dose |of |drug |is |administered
T-max |- |CORRECT |ANSWER✔✔-time |to |maximum |(peak) |drug |level |after |a |drug |is |
administered
C-max |- |CORRECT |ANSWER✔✔-maximum |(peak) |concentration |of |a |drug |after |it |is |
administered
First-Pass |effect |- |CORRECT |ANSWER✔✔-Some |drugs, |when |passing |from |the |intestines |to |the |
liver, |get |metabolized |with |only |part |of |drug |dose |reaching |systemic |circulation |for |distribution
Bio-availability |- |CORRECT |ANSWER✔✔-% |of |drug |that |reaches |systemic |circulation |after |an |
administered |dose. |Used |to |determine |drug |dose.
Potency |- |CORRECT |ANSWER✔✔-a |relative |measure |that |compares |the |doses |of |2 |different |
drugs |that |are |required |to |achieve |the |same |effect
Half-Life |- |CORRECT |ANSWER✔✔-the |time |required |for |the |serum |concentration |of |a |drug |to |
decrease |by |50%
Efficacy |- |CORRECT |ANSWER✔✔-The |maximum |effect |a |drug |can |achieve
