CHEM 232 - Exam 3 Questions
and Answers 100% PASS
Alcohol Activation does what? - CORRECT ANSWER-Transform alcohol into
good leaving group
Dehydration uses what? - CORRECT ANSWER-Heat
Dehydration mechanism - CORRECT ANSWER-E1 unless super super extreme
heat
If there is a pyridine or HX present do what? - CORRECT ANSWER-Acid - Base
PBr3/PCl3 what does it do? (generally) - CORRECT ANSWER-Substitute the
alcohol with a good leaving group
SOCl2 what does it do? (generally) - CORRECT ANSWER-Substitute the alcohol
with a good leaving group
Sulfonyl Chlorides what does it do? (generally) - CORRECT ANSWER-Substitute
the alcohol with a good leaving group
What two activation reagents use SnAc? - CORRECT ANSWER-SOCl2 and
sulfonyl chlorides
, Key things to have with SnAc mechanism - CORRECT ANSWER-Need Carbonyl
connected to a good leaving group and R group
What should I do if my Ephile does not have a good leaving group for a SnAc
mechanism? - CORRECT ANSWER-Activate it if it is an alcohol!!!! Then proceed
with SnAc.
When does carbocations occur? - CORRECT ANSWER-secondary and tertiary
alcohols as well as secondary and tertiary ethers when given the change
If there is pyridine... - CORRECT ANSWER-sweep up them extra mf proton
charges
Ether formation products - CORRECT ANSWER-Alkoxides + alkyl halides
(methyl or primary unhindered only)
Strong bases - CORRECT ANSWER-Charged CNO
Alkoxide + primary hindered or above - CORRECT ANSWER-No ether for you!
Only E2
SOCl2, pyridine, what are the mechanisms that take place? - CORRECT
ANSWER-Acid base, SN2, SnAc
Sulfonyl Chlorides, Pyridine, what are the mechanisms that take place? -
CORRECT ANSWER-Acid base, SnAc (No Inversion!!!!)
COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED
and Answers 100% PASS
Alcohol Activation does what? - CORRECT ANSWER-Transform alcohol into
good leaving group
Dehydration uses what? - CORRECT ANSWER-Heat
Dehydration mechanism - CORRECT ANSWER-E1 unless super super extreme
heat
If there is a pyridine or HX present do what? - CORRECT ANSWER-Acid - Base
PBr3/PCl3 what does it do? (generally) - CORRECT ANSWER-Substitute the
alcohol with a good leaving group
SOCl2 what does it do? (generally) - CORRECT ANSWER-Substitute the alcohol
with a good leaving group
Sulfonyl Chlorides what does it do? (generally) - CORRECT ANSWER-Substitute
the alcohol with a good leaving group
What two activation reagents use SnAc? - CORRECT ANSWER-SOCl2 and
sulfonyl chlorides
, Key things to have with SnAc mechanism - CORRECT ANSWER-Need Carbonyl
connected to a good leaving group and R group
What should I do if my Ephile does not have a good leaving group for a SnAc
mechanism? - CORRECT ANSWER-Activate it if it is an alcohol!!!! Then proceed
with SnAc.
When does carbocations occur? - CORRECT ANSWER-secondary and tertiary
alcohols as well as secondary and tertiary ethers when given the change
If there is pyridine... - CORRECT ANSWER-sweep up them extra mf proton
charges
Ether formation products - CORRECT ANSWER-Alkoxides + alkyl halides
(methyl or primary unhindered only)
Strong bases - CORRECT ANSWER-Charged CNO
Alkoxide + primary hindered or above - CORRECT ANSWER-No ether for you!
Only E2
SOCl2, pyridine, what are the mechanisms that take place? - CORRECT
ANSWER-Acid base, SN2, SnAc
Sulfonyl Chlorides, Pyridine, what are the mechanisms that take place? -
CORRECT ANSWER-Acid base, SnAc (No Inversion!!!!)
COPYRIGHT ©️ 2025 ALL RIGHTS RESERVED
