Comprehensive NP Board Prep Practice
Questions with Verified Answers & Detailed
Rationales/NSG 6998 APEA Predictor Exam
with Correct Answers – NP Board Prep
1. A 58-year-old patient with type 2 diabetes presents with numbness
and burning in both feet. The most appropriate first-line medication is:
A. Ibuprofen
B. Gabapentin
C. Prednisone
D. Acetaminophen
Correct Answer: B
Rationale:
Diabetic peripheral neuropathy is best treated initially with gabapentin,
pregabalin, or duloxetine. NSAIDs and acetaminophen are ineffective for
neuropathic pain, and steroids are not indicated.
2. Which finding is MOST concerning in a patient with suspected acute
coronary syndrome (ACS)?
A. BP 148/90 mmHg
B. Troponin elevation
C. Sinus tachycardia
D. Mild nausea
,Correct Answer: B
Rationale:
Elevated troponin indicates myocardial injury and confirms ACS. Vital
sign changes and nausea are nonspecific and less diagnostic.
3. A 32-year-old woman presents with dysuria and urinary frequency.
Urinalysis shows positive nitrites and leukocyte esterase. Best
treatment is:
A. Ciprofloxacin
B. Nitrofurantoin
C. Amoxicillin
D. Doxycycline
Correct Answer: B
Rationale:
Nitrofurantoin is first-line for uncomplicated cystitis in non-pregnant
women. Fluoroquinolones are avoided unless necessary due to
resistance and side effects.
4. Which condition is a contraindication to prescribing combined oral
contraceptives?
A. Migraine without aura
B. Controlled hypertension
C. Migraine with aura
D. Age under 35
Correct Answer: C
,Rationale:
Migraine with aura significantly increases stroke risk when combined
with estrogen-containing contraceptives.
5. A patient with COPD presents with increased sputum production and
dyspnea. The GOLD guideline recommends:
A. Increase inhaled corticosteroids only
B. Short-acting bronchodilator alone
C. Bronchodilator + oral corticosteroid
D. Antibiotics only
Correct Answer: C
Rationale:
COPD exacerbations are treated with bronchodilators plus systemic
corticosteroids, and antibiotics if bacterial infection is suspected.
6. Which lab finding confirms iron deficiency anemia?
A. Elevated ferritin
B. Increased MCV
C. Low ferritin
D. Elevated reticulocyte count
Correct Answer: C
Rationale:
Low ferritin reflects depleted iron stores and is the most specific
indicator of iron deficiency anemia.
, 7. A 6-year-old child presents with sore throat, fever, and strawberry
tongue. Next best step?
A. Supportive care only
B. Rapid strep test
C. Prescribe antiviral therapy
D. CT scan of neck
Correct Answer: B
Rationale:
Symptoms suggest streptococcal pharyngitis or scarlet fever. A rapid
strep test confirms diagnosis before antibiotics.
8. Which medication class slows progression of diabetic nephropathy?
A. Beta blockers
B. Calcium channel blockers
C. ACE inhibitors
D. Loop diuretics
Correct Answer: C
Rationale:
ACE inhibitors (or ARBs) reduce intraglomerular pressure and
proteinuria, slowing kidney damage in diabetes.
9. A patient presents with sudden unilateral leg swelling and pain. The
FIRST diagnostic test is:
A. D-dimer
B. Venous Doppler ultrasound