NSC 830 Advanced Pharm; Thyroid Questions
and Answers (100% Correct Answers) Already
Graded A+
Normal TSH [ Ans: ] 0.5 - 5 mU/L
TSH levels in hypothyroidism are increased or decreased?
[ Ans: ] Increased (body is trying to compensate) it is an
inverse.
T3 and T4 levels in hypothyroidism are increased or
decreased? [ Ans: ] decreased
Natural Thyroid Agents [ Ans: ] Health food stores
Derived from beef and pork thyroid glands
Cheaper "more natural"
DO NOT HAVE CONSISTENT AMOUNTS OF THYROID
HORMONE. (Content and bioavailability vary from dose to
dose)
Serum fluctuations cause cardiac symptoms
Do not substitute this for prescription drug.
NOT REGULATED BY FDA!
Synthetic Thyroid Agents [ Ans: ] Levothyroxine (T4) -
Synthroid, Levoxyl
, 35% of T4 converts to T3
Longer 1/2 life (6-7 days)
How many half lives does it take to reach steady state? [
Ans: ] 4-5 half lives
Initiating Levothyroxine for tx of hypothyroidism [ Ans: ]
Initiate at 50mcg/day
Increase in increments of 25 mcg/day at six week
intervals
Usually up to 100 to 150 mcg/day
Target does is based on TSH levels and patient symptoms
Initiating Levothyroxine for hypothyroidism and the
elderly. [ Ans: ] Initiate at 25 mcg/day
Increase in increments of 12.5-25 mcg/day
Target does based on TSH levels and patient response
ALSO Lower doses a longer intervals for changing doses in
patients with CVD.
Hypothyroidism, levothyroxine and pregnancy [ Ans: ]
May need to increase dose by 25-30% during pregnancy
and check TSH in 4 weeks to determine dosage adjustment
needs.
and Answers (100% Correct Answers) Already
Graded A+
Normal TSH [ Ans: ] 0.5 - 5 mU/L
TSH levels in hypothyroidism are increased or decreased?
[ Ans: ] Increased (body is trying to compensate) it is an
inverse.
T3 and T4 levels in hypothyroidism are increased or
decreased? [ Ans: ] decreased
Natural Thyroid Agents [ Ans: ] Health food stores
Derived from beef and pork thyroid glands
Cheaper "more natural"
DO NOT HAVE CONSISTENT AMOUNTS OF THYROID
HORMONE. (Content and bioavailability vary from dose to
dose)
Serum fluctuations cause cardiac symptoms
Do not substitute this for prescription drug.
NOT REGULATED BY FDA!
Synthetic Thyroid Agents [ Ans: ] Levothyroxine (T4) -
Synthroid, Levoxyl
, 35% of T4 converts to T3
Longer 1/2 life (6-7 days)
How many half lives does it take to reach steady state? [
Ans: ] 4-5 half lives
Initiating Levothyroxine for tx of hypothyroidism [ Ans: ]
Initiate at 50mcg/day
Increase in increments of 25 mcg/day at six week
intervals
Usually up to 100 to 150 mcg/day
Target does is based on TSH levels and patient symptoms
Initiating Levothyroxine for hypothyroidism and the
elderly. [ Ans: ] Initiate at 25 mcg/day
Increase in increments of 12.5-25 mcg/day
Target does based on TSH levels and patient response
ALSO Lower doses a longer intervals for changing doses in
patients with CVD.
Hypothyroidism, levothyroxine and pregnancy [ Ans: ]
May need to increase dose by 25-30% during pregnancy
and check TSH in 4 weeks to determine dosage adjustment
needs.
