Study guides, Class notes & Summaries

Hemoglobin composition 4 heme ( 4 Fe + 1 porphryin) 1 globin ( 2 alpha 2 beta chains) Mw= 64000 Porphyria abnorm of heme synth xs production of intermediate metabolite protein unchanged change in valence of iron or organic group oxyhemoglobin O attaches to Fe ++ ( reduced hgb), replacing water molecule carry O, iron is kept at Fe++ ( ferrous) state by methemoglobin-cytochrome C reductase carboxy hemoglobin binding of CO2 is 200x stronger than for O hea...

AAB Immunology questions and answers.

The core (genome) of the HIV virion contains: A. DNA B. RNA C. Both RNA and DNA D. Neither RNA or DNA B. RNA What two glycoproteins are expressed on the surface of influenza A viruses and are used for subtyping of the viruses? A. Hemagglutinin and Neuraminidase B. Glycoprotein120 (gp120) and Protein 24 (p24) C. Glycoprotein 41 (gp41) and glycoprotein 120 (gp120) D. Neuraminidase and protein 24(p24) A. Hemagglutinin and Neuraminidase A tech is testing a sorbitol negati...

Hemoglobin that has 200 times greater binding capacity for the hemoglobin molecules than oxygen? Carboxyhemoglobin Hemoglobin derivative that cause irreversible changes in the RBC cells Sulfehemoglobin Molecular structure of Hemoglobin S Lysine replaces glutamic acid in the 6th position of the beta chain Lab test to confirm the specific diagnosis of sickle cell anemia? Hemoglobin electrophoresis In Hemoglobin C what replaces glutamic acid? Lysine Which hem...

Hemoglobin that has 200 times greater binding capacity for the hemoglobin molecules than oxygen? Carboxyhemoglobin Hemoglobin derivative that cause irreversible changes in the RBC cells Sulfehemoglobin Molecular structure of Hemoglobin S Lysine replaces glutamic acid in the 6th position of the beta chain Lab test to confirm the specific diagnosis of sickle cell anemia? Hemoglobin electrophoresis In Hemoglobin C what replaces glutamic acid? Lysine Which hem...

CLIA Clinical Laboratory Improvement Amendment Level of testing 1. waived testing 2. Moderate complexity 3. High complexity Waived Testing-requirement/criteria Waived tests include test systems cleared by the FDA for home use and those tests approved for waiver under the CLIA criteria. Although CLIA requires that waived tests must be simple and have a low risk for erroneous results, this does not mean that waived tests are completely error-proof. Errors can occur anywhere in t...

Nucleic Acid grows by attachment of 5' phosphate group of the incoming nucleotide to the 3'hydroxyl group of the last nucleotide double stranded DNA most energetically favorable state for DNA Purines double-ring structure Adenine (A) + Guanine (G) Pyrimidine single-ring structure Uracil (U)+ Cytosine Messenger RNA (mRNA) -template for all protein synthesis -encode all information necessary to produce proteins Heterogeneous nuclear RNA primary product o...

Bacillus anthracis Disease Anthrax. Primarily disease of herbivores/ruminants- cows. Cutaneous anthrax most common; GI and inhalation possible but not common. Those have 100% fatality. Bacillus anthracis Characteristics Aerobic, gram-positive, spore-forming rods. Capsule composed of poly-D-glutamate. B. anthracis is the only medically important organism that has a capsule composed of amino acids rather than polysaccharides. Bacillus anthracis Habitat and Transmission Habitat is ...

All of the following blood donors would be permanently deferred except which one? 38yr old male who received rabies vaccine after a dog bite 3mos ago What is the interval blood donations? 8 weeks The oral temperature of a donor must not exceed which value? 37.5C 99.5F What is the minimum acceptable hemoglobin for blood donors? 12.5 g/dL for allogeneic donors What is the lowest acceptable hematocrit for allogeneic blood donors? 38% What donor meets the requ...

What are the the 2 recommended anticoagulants for Plasma or Bone Marrow Aspirate Samples EDTA and ACD Why is EDTA one of the recommended coagulants for Plasma or Bone marrow aspirate samples 1)A chelating (binding) agent for divalent cations such as Mg++ or Ca++ 2)Helps deactivate metal-dependent enzymes 3)Suppresses damage to DNA and proteins by deoxyribonucleases 4)Allows DNA to remain in native state and large molecular size before extraction What does EDTA stand for? ethy...