AAB MT Study guides, Class notes & Summaries
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AAB Hematology questions and answers.
- Exam (elaborations) • 134 pages • 2024
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Hemoglobin composition 
4 heme ( 4 Fe + 1 porphryin) 
1 globin ( 2 alpha 2 beta chains) 
Mw= 64000 
 
 
 
Porphyria 
abnorm of heme synth 
 
xs production of intermediate metabolite 
 
 
 
protein unchanged 
change in valence of iron or organic group 
 
 
 
oxyhemoglobin 
O attaches to Fe ++ ( reduced hgb), replacing water molecule 
 
carry O, iron is kept at Fe++ ( ferrous) state by methemoglobin-cytochrome C reductase 
 
 
 
carboxy hemoglobin 
binding of CO2 is 200x stronger than for O 
 
hea...
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AAB Immunology questions and answers.
- Exam (elaborations) • 44 pages • 2024
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AAB Immunology questions and answers.
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AAB MT Microbiology Review questions and answrs
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The core (genome) of the HIV virion contains: 
 
A. DNA 
B. RNA 
C. Both RNA and DNA 
D. Neither RNA or DNA 
B. RNA 
 
 
 
What two glycoproteins are expressed on the surface of influenza A viruses and are used for subtyping of the viruses? 
 
A. Hemagglutinin and Neuraminidase 
B. Glycoprotein120 (gp120) and Protein 24 (p24) 
C. Glycoprotein 41 (gp41) and glycoprotein 120 (gp120) 
D. Neuraminidase and protein 24(p24) 
A. Hemagglutinin and Neuraminidase 
 
 
 
A tech is testing a sorbitol negati...
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AAB Basic Knowledge-MT questions and answers(latest update).
- Exam (elaborations) • 10 pages • 2024
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Hemoglobin that has 200 times greater binding capacity for the hemoglobin molecules than oxygen? 
Carboxyhemoglobin 
 
 
 
Hemoglobin derivative that cause irreversible changes in the RBC cells 
Sulfehemoglobin 
 
 
 
Molecular structure of Hemoglobin S 
Lysine replaces glutamic acid in the 6th position of the beta chain 
 
 
 
Lab test to confirm the specific diagnosis of sickle cell anemia? 
Hemoglobin electrophoresis 
 
 
 
In Hemoglobin C what replaces glutamic acid? 
Lysine 
 
 
 
Which hem...
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AAB Hematology Board review questions and answrs(latest upate)
- Exam (elaborations) • 24 pages • 2024
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Hemoglobin that has 200 times greater binding capacity for the hemoglobin molecules than oxygen? 
Carboxyhemoglobin 
 
 
 
Hemoglobin derivative that cause irreversible changes in the RBC cells 
Sulfehemoglobin 
 
 
 
Molecular structure of Hemoglobin S 
Lysine replaces glutamic acid in the 6th position of the beta chain 
 
 
 
Lab test to confirm the specific diagnosis of sickle cell anemia? 
Hemoglobin electrophoresis 
 
 
 
In Hemoglobin C what replaces glutamic acid? 
Lysine 
 
 
 
Which hem...
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AAB: BASIC KNOWLEDGE- REGULATORY COMPLIANCE questions and answrs(latest upate)
- Exam (elaborations) • 63 pages • 2024
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CLIA 
Clinical Laboratory Improvement Amendment 
 
 
 
Level of testing 
1. waived testing 
2. Moderate complexity 
3. High complexity 
 
 
 
Waived Testing-requirement/criteria 
Waived tests include test systems cleared by the FDA for home use and those tests approved for waiver under the CLIA criteria. Although CLIA requires that waived tests must be simple and have a low risk for erroneous results, this does not mean that waived tests are completely error-proof. Errors can occur anywhere in t...
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AAB Molecular Diagnostics- Nicole's questions and answers
- Exam (elaborations) • 77 pages • 2024
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Nucleic Acid 
grows by attachment of 5' phosphate group of the incoming nucleotide to the 3'hydroxyl group of the last nucleotide 
 
 
 
double stranded DNA 
most energetically favorable state for DNA 
 
 
 
Purines 
double-ring structure Adenine (A) + Guanine (G) 
 
 
 
Pyrimidine 
single-ring structure Uracil (U)+ Cytosine 
 
 
 
Messenger RNA (mRNA) 
-template for all protein synthesis 
-encode all information necessary to produce proteins 
 
 
 
Heterogeneous nuclear RNA 
primary product o...
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AAB Gram positive cocci questions and answers
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Bacillus anthracis Disease 
Anthrax. Primarily disease of herbivores/ruminants- cows. Cutaneous anthrax most common; GI and inhalation possible but not common. Those have 100% fatality. 
 
 
 
Bacillus anthracis Characteristics 
Aerobic, gram-positive, spore-forming rods. Capsule composed of poly-D-glutamate. B. anthracis is the only medically important organism that has a capsule composed of amino acids rather than polysaccharides. 
 
 
 
Bacillus anthracis Habitat and Transmission 
Habitat is ...
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MT AAB Immunohematology questions and answrs
- Exam (elaborations) • 58 pages • 2024
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All of the following blood donors would be permanently deferred except which one? 
38yr old male who received rabies vaccine after a dog bite 3mos ago 
 
 
 
What is the interval blood donations? 
8 weeks 
 
 
 
The oral temperature of a donor must not exceed which value? 
37.5C 99.5F 
 
 
 
What is the minimum acceptable hemoglobin for blood donors? 
12.5 g/dL for allogeneic donors 
 
 
 
What is the lowest acceptable hematocrit for allogeneic blood donors? 
38% 
 
 
 
What donor meets the requ...
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AAB Molecular Review questions and answrs(latest update)
- Exam (elaborations) • 20 pages • 2024
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What are the the 2 recommended anticoagulants for Plasma or Bone Marrow Aspirate Samples 
EDTA and ACD 
 
 
 
Why is EDTA one of the recommended coagulants for Plasma or Bone marrow aspirate samples 
1)A chelating (binding) agent for divalent cations such as Mg++ or Ca++ 
2)Helps deactivate metal-dependent enzymes 
3)Suppresses damage to DNA and proteins by deoxyribonucleases 
4)Allows DNA to remain in native state and large molecular size before extraction 
 
 
 
What does EDTA stand for? 
ethy...
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