NCLEX UWorld Pharmacology Questions and Answers Rated A Nephrotoxic Meds ✔✔-mycin anti biotics (aminoglycides) -keterolac (Toradol) -NSAIDs -digoxin Hepatotoxic Meds ✔✔-tylenol -NSAIDs Naloxone (Narcan) ✔✔-weans in 1 -2 hours -IV or nasal spray -if unresponsive d/t anesthesia or opioids: administer oxygen, assess respiratory rate, notify H CP, prepare second dose Narcan, no need to call rapid response/code team NSAIDs ✔✔NON -STEROIDAL ANTI -INFLAMMATORY DRUGS -ex: aspirin, ibuprofen, naproxen -use at lowest dose necessary for short amount of time -risks: GI toxicity, kidney injury, HTN, heart failure, bleeding risk -do not use if hx cardiac problems Aspirin ✔✔-side effects: black tarry stools, ringing in ears (earliest sign), bruising, tachycardia, hypotension -ASA toxicity: treated with activated charcoal then IV sodium bicarbonate, sx disorientation/vomiting/diaphoresis/restlessness, tinnitus Opioids ✔✔-if taking extended release for chronic pain teach to take even if pain is not present -monitor respiratory status when taking with short acting opioids -IV 2-3 minute push then check 15 -30 minutes after admin -nausea/vomiting usually subsides after initial treatment -take with food EX -morphine -hydrocodone -codeine -fentanyl -heroin (illegal substance) SE -sedation -respiratory depression -hypo tension -constipation -risk for addiction Codeine ✔✔-narcotic used for acute pain or cough suppressant -can cause accumulation of secretions so do not prescribe to people with respiratory disorders Topical Medications ✔✔-allow 30 minutes before washing off to ensure medication is absorbed -avoid heat -local irritation is common Clozapine ✔✔-antipsychotic
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