Study guides, Class notes & Summaries

The clotting cascade consists of the series of steps that occur by our body to prevent the excessive loss of blood from the body (hemostasis) The clotting cascade consists of the intrinsic and extrinsic pathways. These pathways lead to the activation of clotting factor 5 which is referred to as "pro-thrombin activator". The pro-thrombin activator results in the conversion of the pro-thrombin into thrombin wit the help pf Ca 2 ion. The excess of thrombin in the body causes the fibrinogen to t...

The clotting cascade may be defined as the series of events that occur by our platelets, under the influence of an activated immune system, in order to form a blood clot to prevent the excessive loss of blood from the body (Hemostasis) The clotting factors are substances which take part in the process of coagulation. Most of them are synthesized in the Liver. Their availability is extremely important in the body as their deficiency can cause several bleeding disorders. The clotting cascade cons...