cellular pathology

Notes on the calcification on the grwoth plate and vascular pathologic calcification for a cellular pathology and special topics in pathobiology module taught on the third year of a biomedical science degree course. These notes explore the possibility that calcification in the growth plate may be a model for pathological calcification in the vasculature, the similarities in mechanisms of calcification between the growth plate and the vasculature are discussed including the role of transcription ...

Notes covering a cellular pathology module taught on the third year of a biomedical science degree course. Topics covered include; rheumatoid arthritis, inflammation and cancer, the tumour microenvironment, oxidative stress and kidney injury, medical imaging, nuclear medicine, molecular diagnostics, oxidative stress and diabetic neuropathy, pathological calcification, and the growth plate calcification and vascular calcification.

Notes on the topic of pathological calcification for a cellular pathology taught on the third year of a biomedical science degree. Notes cover; bone physiology, calcium homeostasis, the action of parathyroid hormone, secondary hyperparathyroidism, techniques to prepare bone tissue sections, the basics of pathological calcification, dystrophic calcification, and metastatic calcification.

Notes covering the topic of diabetic neuropathy, for a cellular pathology module taught on the third year of a biomedical science degree course. Notes cover; the role and vulnerability of the dorsal root ganglia in diabetic neuropathy, the clinical presentation of diabetic neuropathy, and the pathophysiology of diabetic neuropathy with a focus on the role of the polyol pathway, AGE products and the mitochondria.

Notes on the topic of molecular diagnostics, in particular nucleic acid and protein based diagnostic methods, for a cellular pathology module taught on the third year of a biomedical degree course. These notes cover the concept of genomics, transcriptomics, personalized medicine,pharmacogenomics, the human genome, the human proteome, proteomics, the proteome, and biomarkers. These notes cover the methods and applications of the following nucleic acid based diagnostic tests; Maxam-Gilbert method ...

Notes on the topic of nuclear medicine taught in a cellular pathology module in the third year of a biomedical science degree. The notes cover the nuclear imaging modalities single photon emission computed tomography and positron emission tomography, and discusses the principles behind each method, the clinical applications, and advantages and disadvantages of each modality.

Notes on the topic of medical imaging for a cellular pathology module taught on the third year of a biomedical science degree. These notes discuss; x-ray, CT, MRI, and ultrasound imaging modalities, covering the principles,application, advantages and disadvantages of each imaging technique.

Notes on the topic of oxidative stress and its role in kidney injury for a cellular pathology module taught in the third year of a biomedical science degree. These notes cover; free radicals, cellular defence mechanisms against free radicals, the generation of free radicals, and the toxic effects of free radicals. In addition, these notes cover acute and chronic kidney disease. These notes discuss renal ischaemia-perfusion injury and pharmacological treatment of renal ischaemia-perfusion injury....

Notes of the tumour microenvironment for a cellular pathology module in the third year if a biomedical science degree course. These notes cover; the tumour microenvironment, myeloid derived suppressor cells, tumour associated macrophages, regulatory T cells in the tumour microenvironment, extracellular vesicles and their role in the tumour microenvironment, and cancer associated fibroblasts.