Part II Pathology Immunology
Cambridge University (CAM)
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MHC genetics and disease
- Class notes • 18 pages • 2020
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MHC gene diversity: mechanisms of creation and maintenance 
Disease associations of MHC with:
- Infectious disease
- Autoimmunity
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MHC II Presentation
- Class notes • 34 pages • 2020
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Processing of pathways for MHC II presentation
Structure of MHC II 
Effect of MHCII-peptide presentation
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Monocytes and Macrophages
- Class notes • 13 pages • 2020
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Ontogeny of myeloid cells 
How function varies in development 
Subsets of monocytes and macrophages
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Additional DC cells
- Class notes • 15 pages • 2020
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DC functions and activation
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NK cells
- Class notes • 39 pages • 2020
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Natural killer cell functions
NK receptors regulating activity 
NK genes
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Post-transcriptional gene expression in innate immunity
- Class notes • 6 pages • 2020
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Importance of post-transcriptional regulation in activating and inactivating innate immunity
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Reproductive Immunology
- Class notes • 40 pages • 2020
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immune cells at the maternal-fetal interface 
How tolerance to the fetus is maintained 
Pre-eclampsia and failure of placentation
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Structure and function of classical and non-classical MHC
- Class notes • 8 pages • 2020
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Differences in the structure of classical and non-classical MHC, and how this relates to their differing function
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T cell differentiation
- Class notes • 23 pages • 2020
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T helper subsets, their function and mechanisms of promoting differentiation
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TCR Triggering Mechanisms
- Class notes • 6 pages • 2020
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Theories of how TCR signalling is triggered, and evidence supporting these
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