Page 1 of 63
NR507 MID-TERM EXAM (CHAMBERLAIN) NEWEST
2025 PACKAGE DEAL| NR 507 ADVANCED
PATHOPHYSIOLOGY EXAMS WITH COMPLETE REAL
EXAM QUESTIONS AND CORRECT VERIFIED ANSWERS/
ALREADY GRADED A+ (MOST RECENT!!)
Housekeeping genes are vital to the function and maintenance of
all the body's cells. What characteristic is associated with these
genes? .....ANSWER.....D. They are transcriptionally active.
Mutations in the encoding of histones modifying proteins have
been shown to influence the development of what congenial
condition .....ANSWER.....Heart disease
Signals to change or modify epigenetic tags are ... from where?
.....ANSWER.....Signals come from inside the cell, from
neighboring cells or the environment
,Page 2 of 63
During which stage of human development does the role of
epigenetics have the greatest impact on the development of
epigenetic abnormalities .....ANSWER.....A. In utero
The difference between DNA sequence mutations and epigenetic
modifications is? .....ANSWER.....Epigenetic modifications are
REVERSIBLE
Explain the characteristics of totipotent stem cells and the sources
of it .....ANSWER.....Totipotent cells are cells that can mature into
any type of body cell in an organism including the cells that
make up the placenta in mammals. Totipotent cells are only
present in mammals in the first few cell divisions of an embryo.
Give 2 examples of totipotent cells .....ANSWER.....A zygote
Cells in the early embyro up to 5 days
What is a Totipotent cell? .....ANSWER.....Totipotent cells are cells
that can differentiate into any type of body cell and extra
embryonic tissue
,Page 3 of 63
What are the characteristics of Prader-Willi syndrome?
.....ANSWER.....1. Chronic feeling of hunger (severe, even life-
threatening obesity)
2. Low muscle tone
3. Short
4. Poor sex characteristic development
5. Behavioral problems
6. Poor cognitive development
Angelman syndrome is sometimes called "happy puppet
syndrome." What are the signs of this disorder? .....ANSWER.....1.
Severe mental retardation
2. No speech
3. Abnormal gait
4. Wide stance
, Page 4 of 63
5. Arms held out kinda weird
What is the most common genetic cause of Prader-Willi
syndrome? .....ANSWER.....A deletion of a segment of PATERNAL
chromosome 15q. The maternal counterpart is methylated via
genomic imprinting.
What is the most common genetic cause of Angelman syndrome?
.....ANSWER.....A deletion of a segment of MATERNAL
chromosome 15q. The paternal counterpart is methylated via
genomic imprinting.
A child with Prader-Willi syndrome has been hospitalized. Which
assessment findings does the nurse expect with this syndrome?
.....ANSWER.....Prader-Willi syndrome is characterized by
insatiable hunger that can lead to morbid obesity in childhood.
Abnormal, puppetlike gait, paroxysms of inappropriate laughter,
and nonverbal are characteristics seen in Angelman syndrome.
NR507 MID-TERM EXAM (CHAMBERLAIN) NEWEST
2025 PACKAGE DEAL| NR 507 ADVANCED
PATHOPHYSIOLOGY EXAMS WITH COMPLETE REAL
EXAM QUESTIONS AND CORRECT VERIFIED ANSWERS/
ALREADY GRADED A+ (MOST RECENT!!)
Housekeeping genes are vital to the function and maintenance of
all the body's cells. What characteristic is associated with these
genes? .....ANSWER.....D. They are transcriptionally active.
Mutations in the encoding of histones modifying proteins have
been shown to influence the development of what congenial
condition .....ANSWER.....Heart disease
Signals to change or modify epigenetic tags are ... from where?
.....ANSWER.....Signals come from inside the cell, from
neighboring cells or the environment
,Page 2 of 63
During which stage of human development does the role of
epigenetics have the greatest impact on the development of
epigenetic abnormalities .....ANSWER.....A. In utero
The difference between DNA sequence mutations and epigenetic
modifications is? .....ANSWER.....Epigenetic modifications are
REVERSIBLE
Explain the characteristics of totipotent stem cells and the sources
of it .....ANSWER.....Totipotent cells are cells that can mature into
any type of body cell in an organism including the cells that
make up the placenta in mammals. Totipotent cells are only
present in mammals in the first few cell divisions of an embryo.
Give 2 examples of totipotent cells .....ANSWER.....A zygote
Cells in the early embyro up to 5 days
What is a Totipotent cell? .....ANSWER.....Totipotent cells are cells
that can differentiate into any type of body cell and extra
embryonic tissue
,Page 3 of 63
What are the characteristics of Prader-Willi syndrome?
.....ANSWER.....1. Chronic feeling of hunger (severe, even life-
threatening obesity)
2. Low muscle tone
3. Short
4. Poor sex characteristic development
5. Behavioral problems
6. Poor cognitive development
Angelman syndrome is sometimes called "happy puppet
syndrome." What are the signs of this disorder? .....ANSWER.....1.
Severe mental retardation
2. No speech
3. Abnormal gait
4. Wide stance
, Page 4 of 63
5. Arms held out kinda weird
What is the most common genetic cause of Prader-Willi
syndrome? .....ANSWER.....A deletion of a segment of PATERNAL
chromosome 15q. The maternal counterpart is methylated via
genomic imprinting.
What is the most common genetic cause of Angelman syndrome?
.....ANSWER.....A deletion of a segment of MATERNAL
chromosome 15q. The paternal counterpart is methylated via
genomic imprinting.
A child with Prader-Willi syndrome has been hospitalized. Which
assessment findings does the nurse expect with this syndrome?
.....ANSWER.....Prader-Willi syndrome is characterized by
insatiable hunger that can lead to morbid obesity in childhood.
Abnormal, puppetlike gait, paroxysms of inappropriate laughter,
and nonverbal are characteristics seen in Angelman syndrome.
