Advanced Pharmacology I | Questions with Verified
Answers| 100% Correct| Graded A- Bradley University.
Question:
This is the Study and measurement of responses of the body to drugs.
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
(What the drug does to the body)
i,- i,- i,- i,- i,- i,-
1. Pharmacodynamics
i,-
2. Pharmacokinetics
i,-
3. Therapeutics?
i,-
Answer:
1. Pharmacodynamics
i,-
Question:
What is the weakest type of bond between drug and receptor?
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
1. Hydrogen
i,-
2. van der Waals
i,- i,- i,-
3. Covalent
i,-
4. Ionic?
i,-
Answer:
2. Van der Waals
i,- i,- i,-
,Question:
Most drugs have molecular targets, what are the two examples of drugs
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
that do not?
i,- i,-
1. Opioids and NSAIDS
i,- i,- i,-
2. Antacids in the stomach and Volatile general anesthetics
i,- i,- i,- i,- i,- i,- i,- i,-
3. OTC cold medications and inhaled Corticosteroids
i,- i,- i,- i,- i,- i,-
4.Some Blood Pressure Medications and Laxatives?
i,- i,- i,- i,- i,-
Answer:
2. Antacids in the stomach and Volatile general anesthetics
i,- i,- i,- i,- i,- i,- i,- i,-
Question:
The drug Valacyclovir is absorbed in the body by which mechanism of
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
transport?
1. Passive
i,-
2. Active
i,-
3. Facilitated?
i,-
Answer:
2. Active Transport
i,- i,-
The drug valacyclovir, an antiviral, has an amino acid attached to acyclovir.
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
This allows for active transport of the drug from the GI tract through
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
,amino acid receptors and thus more acyclovir gets to the site of action in
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
the body.
i,-
Question:
Which is the most common method of absorption into the body by the
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
oral route?
i,-
1. Facilitated Transport
i,- i,-
2. Active Transport
i,- i,-
3. Passive Diffusion?
i,- i,-
Answer:
3. Passive Diffusion
i,- i,-
Question:
T/F: In the blood brain barrier, capillaries have tight junctions that limit the
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
entry of lipid soluble substances.?
i,- i,- i,- i,-
Answer:
False
Capillaries have tight junctions that limit the entry of WATER soluble
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
substances.
Question:
, Which enzymes are ) are responsible for drug metabolism in the liver??
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
Answer:
The P450 (CYP) ezymes
i,- i,- i,-
Question:
Alcohol consumption and smoking are liver enzyme inducers or
i,- i,- i,- i,- i,- i,- i,- i,- i,-
inhibitors??
Answer:
inducers: i,-
This can metabolize the drug more quickly resulting in a less therapeutic
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
outcome
Question:
Grapefruit juice is a liver enzyme inhibitor and people currently taking
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
which drugs should avoid drinking this.?
i,- i,- i,- i,- i,-
Answer:
People taking statins, "ine's", verapamil, 17 B estradiol, and
i,- i,- i,- i,- i,- i,- i,- i,- i,-
dihydropyridine calcium channel blockers should avoid grapefruit juice
i,- i,- i,- i,- i,- i,- i,- i,-
because it may metabolize the drug slower which may lead to toxicity of
i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,- i,-
the drug.
i,-
Question: