Page 1 of 89
FNP PHARMACOLOGY AANP EXAM NEWEST 2025
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EXAM QUESTIONS AND CORRECT DETAILED ANSWERS
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PHARMACOLOGY FOR AANP EXAM PREP 2025
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What are the safety issues caused by taking Phenytoin (Dilantin)?
.....ANSWER..... 1.) Earliest sign of toxicity: horizontal nystagmus
and unsteady gait
2.) If severe, slurred speech, lethargy, confusion, and coma
3.) monitor blood levels
4.) can also cause gingival hyperplasia
BEERS Criteria: Medications that should be avoided in patients
over 65 years? .....ANSWER..... 1.) 1st generation anti-histamines
(diphenhydramine, doxylamine, chlorpheniramine)
,Page 2 of 89
2.) Anti-psychotics: Quetiapine, Clozapine, Pimavaserin (use with
caution)
3.) Rivaroxaban & Dabigatran- Increased risk of bleeding
4.) Tramadol- risk of hyponatremia from syndrom of
inappropriate antidiuretic hormone secretion
5.) Opioids- do not combine with BZDs or Gabapentinoids- will
induce respiratory depression
What safety issues can occur when taking atypical antipsychotics
such as: Risperidone (Risperidal), Olanzapine (Zyprexa), and
Quetiapine (Seroquel)? .....ANSWER..... - High risk of weight gain,
metabolic syndrome, and type 2 diabetes
- monitor weight every 3 months
- higher mortality in elderly patients
- monitor TSH, Blood glucose/A1C, weight/BMI
,Page 3 of 89
What safety issues can be caused by taking TZDs: Pioglitazone
(Actos)? .....ANSWER..... Black box warning! - can cause or
exacerbate CHF
- do not use if class III or IV, heart failure contraindications
-do not use if hx of MI, CVA, bladder ca, type 2 DM, eye or liver
problems,
- do not use if causes dyspnea, wt gain, or cough (signs of heart
failure)
What safety issues can be caused by taking Vitamin K
antagonist: Warfarin (Coumadin)? .....ANSWER..... - Interacts with
"G" herbs such as garlic, ginger, gingko, ginseng, and other
herbs, supplements like feverfew, green tea, and fish oil
-numerous drug interactions
-discontinue at least 7 days before surgery
, Page 4 of 89
What safety issues can be caused by PPIs: Omeprazole
(Prilosec)? .....ANSWER..... - Increased risk of fractures
(postmenopausal women)
-Pneumonia
-C.Diff infection
-hypomagnesemia
-B12 and Iron malabsorption
-atrophic gastritis
-kidney disease
-interacts with warfarin (Coumadin), diazepam (Valium),
Carbamazepine (Tegretol), Phenytoin (Dilantin) and
ketoconazole (Nizoral)
What safety issues can be caused by H2 antagonists: Famotidine
(Pepcid), Cimetidine (Tagamet), Nizatidine (Axid)?
FNP PHARMACOLOGY AANP EXAM NEWEST 2025
ACTUAL EXAM TEST BANK| COMPLETE 300 REAL
EXAM QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) GRADED A+| FNP
PHARMACOLOGY FOR AANP EXAM PREP 2025
(NEW!!)
What are the safety issues caused by taking Phenytoin (Dilantin)?
.....ANSWER..... 1.) Earliest sign of toxicity: horizontal nystagmus
and unsteady gait
2.) If severe, slurred speech, lethargy, confusion, and coma
3.) monitor blood levels
4.) can also cause gingival hyperplasia
BEERS Criteria: Medications that should be avoided in patients
over 65 years? .....ANSWER..... 1.) 1st generation anti-histamines
(diphenhydramine, doxylamine, chlorpheniramine)
,Page 2 of 89
2.) Anti-psychotics: Quetiapine, Clozapine, Pimavaserin (use with
caution)
3.) Rivaroxaban & Dabigatran- Increased risk of bleeding
4.) Tramadol- risk of hyponatremia from syndrom of
inappropriate antidiuretic hormone secretion
5.) Opioids- do not combine with BZDs or Gabapentinoids- will
induce respiratory depression
What safety issues can occur when taking atypical antipsychotics
such as: Risperidone (Risperidal), Olanzapine (Zyprexa), and
Quetiapine (Seroquel)? .....ANSWER..... - High risk of weight gain,
metabolic syndrome, and type 2 diabetes
- monitor weight every 3 months
- higher mortality in elderly patients
- monitor TSH, Blood glucose/A1C, weight/BMI
,Page 3 of 89
What safety issues can be caused by taking TZDs: Pioglitazone
(Actos)? .....ANSWER..... Black box warning! - can cause or
exacerbate CHF
- do not use if class III or IV, heart failure contraindications
-do not use if hx of MI, CVA, bladder ca, type 2 DM, eye or liver
problems,
- do not use if causes dyspnea, wt gain, or cough (signs of heart
failure)
What safety issues can be caused by taking Vitamin K
antagonist: Warfarin (Coumadin)? .....ANSWER..... - Interacts with
"G" herbs such as garlic, ginger, gingko, ginseng, and other
herbs, supplements like feverfew, green tea, and fish oil
-numerous drug interactions
-discontinue at least 7 days before surgery
, Page 4 of 89
What safety issues can be caused by PPIs: Omeprazole
(Prilosec)? .....ANSWER..... - Increased risk of fractures
(postmenopausal women)
-Pneumonia
-C.Diff infection
-hypomagnesemia
-B12 and Iron malabsorption
-atrophic gastritis
-kidney disease
-interacts with warfarin (Coumadin), diazepam (Valium),
Carbamazepine (Tegretol), Phenytoin (Dilantin) and
ketoconazole (Nizoral)
What safety issues can be caused by H2 antagonists: Famotidine
(Pepcid), Cimetidine (Tagamet), Nizatidine (Axid)?
