aterial
Chapterb1: s s Introduction s s to
Drugs
, ss s s
aterial
Chapterb1: s s Introduction s s to
Drugs
Cognitive Level: Application Diffic ss ss ss
ulty: Moderate
ss s s
Integrated Process: Nursing process ss s s ss
1.A nurse working inbradiology administers iodine to a patient who is having a comput
ss ss ss ss ss ss ss ss ss ss ss ss ss
erized axial tomography (CAT) scan. A nurse working on an oncology unit
ss ss ss ss ss ss ss ss ss ss ss ss
administ ers chemotherapy to patientsbwho have cancer. At the Public Health
ss ss ss ss ss ss ss ss ss ss ss
Department, a n urse administers a measles-mumps-rubella (MMR) vaccine to a
ss ss ss ss ss ss ss ss ss ss ss
14-bmonth-
ss
old child as a routine immunization. Which branch of pharmacology best describes
ss ss ss ss ss ss ss ss ss ss ss
t hebactions of all three nurses?
ss ss ss ss ss ss
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Response:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involvedss ss ss ss ss ss ss ss ss ss ss ss
wi th clinical pharmacology or pharmacotherapeutics, which is a branch of
ss ss ss ss ss ss ss ss ss ss ss
pharmacology that deals with the uses of drugs to treat, prevent, and diagnose
ss ss ss ss ss ss ss ss ss ss ss ss ss
disease. The nursebwor king in radiology isbadministering a drug to help diagnose a
ss ss ss ss ss ss ss ss ss ss ss ss ss
disease. Thebnurse workin g on an oncology unit is administering a drug to help treat a
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
disease. Pharmacoeconomi cs includes any costs involved in drug therapy.
ss ss ss ss ss ss ss ss ss ss
Pharmacodynamics involves how a drug affects the body, and pharmacokinetics isbho ss ss ss ss ss ss ss ss ss ss
w the body acts on the drug.
ss ss ss ss ss ss ss
Cognitive Level: Comprehension Di ss ss ss
fficulty: Easy
ss s s
Integrated Process: Nursing process ss s s ss
2.A physician has ordered intramuscular injections of morphine, a narcotic, every 4
ss ss ss ss ss ss ss ss ss ss ss
hour s as needed for pain for a motor vehicle accident victim. The nurse isbaware that
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
there is a high abusebpotentialbfor this drug; therefore, morphine is categorized as a:
ss ss ss ss ss ss ss ss ss ss ss ss ss
A) Schedule I drug ss ss
B) Schedule II drug ss ss
C) Schedule III drug ss ss
D) Schedule IV drug ss ss
Ans: B
Response:
Narcotics such asbmorphinebare considered schedule II drugs because of thebhigh abuse
ss ss ss ss ss ss ss ss ss ss
potential with severe dependence liability. Schedule I drugs have high abuse
ss ss ss ss ss ss ss ss ss ss ss
potential and no accepted medical use. Schedule III drugs have a lesser abuse
ss ss ss ss ss ss ss ss ss ss ss ss ss
potentialbthan sch edule II drugs and an accepted medical use. Schedule IV drugs have
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
low abusebpotentia l and limited dependence liability.
ss ss ss ss ss ss ss
Cognitive Level: Comprehension ss ss
ssDifficulty: Easy s s
Integrated Process: Communication and documentation ss s s ss ss
3. A nurse working for a drug company is involved in phase III drug evaluation
ss ss ss ss ss ss ss ss ss ss ss ss ss
, ss s s
aterial
Chapterb1: s s Introduction s s to
ss ss
Drugs might the nurse be responsible for during thisbstage
studies. Which of the following
ss ss ss ss ss ss ss ss ss ss ss
of drug de velopment?
ss ss ss ss
, ss s s
aterial
Chapterb1: s s Introduction s s to
Drugs
A) Workingbwith animalsbwho are given experimental drugs ss ss ss ss ss
B) Monitoring drug effects in patients who are selected to participate in abstudy, wh ss ss ss ss ss ss ss ss ss ss ss ss
o have the diseasebthat the drug is meant to treat
ss ss ss ss ss ss ss ss ss ss
C) Collecting records of symptoms that participants experience while taking a ss ss ss ss ss ss ss ss ss
dru gband determining whether they are caused by the disease or
ss ss ss ss ss ss ss ss ss ss ss
D) thebdrugbInforming healthy, young volunteer participants of possible risks that
ss ss ss ss ss ss ss ss ss
could occur from tak ing an experimental drug
ss ss ss ss ss ss ss ss
Ans: C
Response:
Phase III studiesbinvolve usebof a drug in a vast clinical market where patients are
ss ss ss ss ss ss ss ss ss ss ss ss ss
aske d to record any symptoms they experience while taking the drugs. Nurses may
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
bebrespo nsible for helping collect and analyze the information to be shared with
ss ss ss ss ss ss ss ss ss ss ss ss ss
theb Food and Drug Administration (FDA). Use of animals in drug testing is done in
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
the preclinical tr ials. A select group of patients who are involved in phase II studies
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
participate in studi es where the participants have the disease the drug is intended to
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
treat. These patients a re monitored closely for drugbeffects. Phase I studies involve
ss ss ss ss ss ss ss ss ss ss ss ss ss
healthy human volunteer s who are usually paid for their participation. Nurses may
ss ss ss ss ss ss ss ss ss ss ss ss ss
observe for adversebeffects a nd toxicity.
ss ss ss ss ss ss
Cognitive Level: Comprehension Di ss ss ss
fficulty: Moderate
ss s s
Integrated Process: Nursing Process ss s s ss
4. Which of the following concepts is considered when generic drugs are substituted
ss ss ss ss ss ss ss ss ss ss ss
for brand-name drugs?
ss ss ss
A) Bioavailability
B) Critical concentration ss
C) Distribution
D) Half-life
Ans: A
Response:
Bioavailability isbthebportion of a dose of a drug that reaches the systemic circulation ss ss ss ss ss ss ss ss ss ss ss ss
a nd isbavailable to act onbbody cells. Binders used in a generic drug may notbbe the
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
same as thosebused in the brand-
ss ss ss ss ss ss
name drug. Therefore, the way thebbody breaks down and uses the drug may differ, whi
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
ch may eliminate absubstitution. Critical concentration is the amount of a drug that is
ss ss ss ss ss ss ss ss ss ss ss ss ss ss
n eeded to causeba therapeutic effect.
ss ss ss ss ss ss
Distribution isbthebphasebof pharmacokinetics that involves the movement of a drug to t
ss ss ss ss ss ss ss ss ss ss ss
hebbody's tissues. A drug's half-
ss ss ss ss ss
life isbthebtimebit takes for the amount of drug to decrease to one-half of the peak level.
ss ss ss ss ss ss ss ss ss ss ss ss ss ss ss
Cognitive Level: AnalysisbDifficult ss ss
ssy: Difficult s s
Integrated Process: Teaching/learning ss s s
5.A nurse isbteaching her patient about the use of over-the-
ss ss ss ss ss ss ss ss ss
A) counter (OTC) drugs. Whichbof the following statements best informs the patient about
ss ss ss ss ss ss ss ss ss ss ss
their safebuse?
ss ss
B) ―OTC drugs are products that are available without prescription for self-
ss ss ss ss ss ss ss ss ss ss
treatment of minor complaints.‖
ss ss ss ss
―OTC drugs are considered medications and should be reported on a drugbhistor
ss ss ss ss ss ss ss ss ss ss ss
y.‖ ss
Page s s 2