ONS Chemotherapy Immunotherapy Cer ficate With 16
Ques ons and answers Newest RATED A+ 2025/2026
3 major phases of cell division: - Ans Interphase
Mito c phase
Cytokinesis
3 steps of interphase: - Ans First growth phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
4 phases of mitosis: - Ans Prophase
Metaphase
Anaphase
Telophase
Innate immunity: - Ans Non-specific response, either:
1. Barrier (skin, mucous membranes, flora of skin/gut)
2. Cellular components (phagocytes, natural killer cells, granulocytes, macrophages)
Adap ve immunity: - Ans Follows innate immunity if unsuccessful. Memory immunity,
including:
1. Humoral immunity (produc on of an bodies or immunoglobulins)
2. Cell mediated immunity (dependent upon T cells)
3. Regulatory T -cells (prevent autoimmune reac ons and limit inflammatory responses)
Define muta ons - Ans Varia ons in the nucleo de sequence of a gene
,3 main goals of treatment: - Ans Cure
Control
Pallia on
Define neoadjuvant therapy - Ans Treatment is given prior to surgery to shrink the tumor
Define adjuvant therapy - Ans Addi onal cancer treatment given a7er the primary treatment
to lower the risk that the cancer reoccur
Define condi oning/prepara ve therapy - Ans Treatments used to prepare a pa ent for stem
cell transplanta on
2 types of condi oning therapies: - Ans Myeloabla ve
Nonmyeloabla ve
Define dose density - Ans Drug dose per unit of me
Define dose intensity - Ans Amount of drug delivered over me
How is rela ve dose intensity (RDI) calculated? - Ans By comparing the dose that the pa ent
ACTUALLY received to the planned dose of the standard regimen
How do alkyla ng agents work? - Ans By causing a break in the DNA helix strand, interfering
with DNA replica on and causing cell death
3 subcategories of alkyla ng agents: - Ans 1. Nitrogen mustards
, 2. Pla num-based agents (do not possess an alkyl group but s ll termed alkyla ng agents as
they work similarly)
3. Nitrosoureas
Most common subcategory of alkyla ng agents: - Ans Nitrogen mustards
Common alkyla ng agents: - Ans Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamus ne (Treanda)
Common pla num-based agents: - Ans Cispla n (Pla nol)
Carbopla n (Parapla n)
What is unique about nitrosoureas agents? - Ans Able to cross the blood-brain barrier; can be
effec ve in trea ng some brain tumors
Common nitrosoureas agents: - Ans Carmus ne (BiCNU)
Lomus ne (CeeNu)
Streptozocin (Zanosar)
Hypersensi vity can occur with late doses of: - Ans Carbopla n
These agents are typically categorized as highly emetogenic: - Ans 1. Alkyla ng agents
2. Nitrosoureas
Pre-administra on labs for alkyla ng agents and nitrosoureas: - Ans BUN
Crea nine
Ques ons and answers Newest RATED A+ 2025/2026
3 major phases of cell division: - Ans Interphase
Mito c phase
Cytokinesis
3 steps of interphase: - Ans First growth phase (G1)
Synthesis phase (S phase)
Second growth phase (G2)
4 phases of mitosis: - Ans Prophase
Metaphase
Anaphase
Telophase
Innate immunity: - Ans Non-specific response, either:
1. Barrier (skin, mucous membranes, flora of skin/gut)
2. Cellular components (phagocytes, natural killer cells, granulocytes, macrophages)
Adap ve immunity: - Ans Follows innate immunity if unsuccessful. Memory immunity,
including:
1. Humoral immunity (produc on of an bodies or immunoglobulins)
2. Cell mediated immunity (dependent upon T cells)
3. Regulatory T -cells (prevent autoimmune reac ons and limit inflammatory responses)
Define muta ons - Ans Varia ons in the nucleo de sequence of a gene
,3 main goals of treatment: - Ans Cure
Control
Pallia on
Define neoadjuvant therapy - Ans Treatment is given prior to surgery to shrink the tumor
Define adjuvant therapy - Ans Addi onal cancer treatment given a7er the primary treatment
to lower the risk that the cancer reoccur
Define condi oning/prepara ve therapy - Ans Treatments used to prepare a pa ent for stem
cell transplanta on
2 types of condi oning therapies: - Ans Myeloabla ve
Nonmyeloabla ve
Define dose density - Ans Drug dose per unit of me
Define dose intensity - Ans Amount of drug delivered over me
How is rela ve dose intensity (RDI) calculated? - Ans By comparing the dose that the pa ent
ACTUALLY received to the planned dose of the standard regimen
How do alkyla ng agents work? - Ans By causing a break in the DNA helix strand, interfering
with DNA replica on and causing cell death
3 subcategories of alkyla ng agents: - Ans 1. Nitrogen mustards
, 2. Pla num-based agents (do not possess an alkyl group but s ll termed alkyla ng agents as
they work similarly)
3. Nitrosoureas
Most common subcategory of alkyla ng agents: - Ans Nitrogen mustards
Common alkyla ng agents: - Ans Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamus ne (Treanda)
Common pla num-based agents: - Ans Cispla n (Pla nol)
Carbopla n (Parapla n)
What is unique about nitrosoureas agents? - Ans Able to cross the blood-brain barrier; can be
effec ve in trea ng some brain tumors
Common nitrosoureas agents: - Ans Carmus ne (BiCNU)
Lomus ne (CeeNu)
Streptozocin (Zanosar)
Hypersensi vity can occur with late doses of: - Ans Carbopla n
These agents are typically categorized as highly emetogenic: - Ans 1. Alkyla ng agents
2. Nitrosoureas
Pre-administra on labs for alkyla ng agents and nitrosoureas: - Ans BUN
Crea nine
