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2026 HESI RN Pharmacology Exam – Full Practice Questions with Answers & Clinical Nursing Scenarios

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Prepare for the HESI RN Exam 2026 with this Pharmacology Practice Exam. Includes exam-style questions and detailed answers covering medication classifications, dosage calculations, and nursing considerations. Focuses on critical thinking, prioritization, and real patient care scenarios to reinforce learning. Ideal for nursing students seeking to practice effectively and boost exam confidence.

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Pharmacology HESI Practice Exam 2026 -Questions And Answers Latest
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client who is comatose is admitted after an overdose of baclofen (Lioresal). What
nursing action should the practical nurse (PN) implement? - CORRECT ✔✔✔✔✔
Monitor for signs of respiratory arrest.

A client with Attention-Deficit Hyperactivity Disorder (ADHD) is prescribed amphetamine
(Adderal). Which side effect should the practical nurse (PN) explain is commonly
experienced? - CORRECT ✔✔✔✔✔ Difficulty sleeping

practical nurse (PN) discusses antihypertensive drug therapy with several clients
diagnosed with high blood pressure. To improve client understanding the PN should
emphasize that which medication preserves renal function in a client with diabetes? -
CORRECT ✔✔✔✔✔ Captopril (Capoten).

The practical nurse (PN) should recommend that oral contraceptives be avoided in
which group of women? - CORRECT ✔✔✔✔✔ Women who smoke.

female client with recurring headaches tells the practical nurse (PN) that she has been
taking at least 4 grams of acetaminophen a day. Which laboratory studies should the
PN review for this client? - CORRECT ✔✔✔✔✔ Hepatic enzymes

healthcare provider prescribes cycloplegic and mydriatic ophthalmic drops for a client
who is having a cataract removal what explanation about the drug actions should the
practical nurse (PN) provide the client? - CORRECT ✔✔✔✔✔ Dilates the pupil.

The practical nurse (PN) observes a thick white-coating on the tongue of a client who
takes fluphenazine (Prolixin). What instructions should the P reinforce with the client
about this medication? - CORRECT ✔✔✔✔✔ Brush your teeth and tongue, floss,
gargle, and notify the healthcare provider

An older client who takes risperidone (Risperdal), an antipsychotic, is complaining of
constipation. Which dietary changes should the practical nurse (PN) recommend? -
CORRECT ✔✔✔✔✔ Increase daily green vegetables and bran

35-week gestation primigravida who takes lithium (Eskalith) tells the practical nurse
(PN) that she would like to breastfeed her infant. What information should the PN

, provide to the client? - CORRECT ✔✔✔✔✔ The drug is excreted in breast milk so
use formula to feed the infant.

The practical nurse (PN) is unable to arouse a client who is receiving meperidine
(Demerol) for postoperative pain. The client is stuporous, has constricted pupils, and a
respiratory rate of 8 breaths/minute. Which PRN prescription should the PN give the
client? - CORRECT ✔✔✔✔✔ Naloxone (Narcan)

client who returns from surgery for bowel resection complains of severe pain around the
incision. Which assessment is most important for the practical nurse obtain prior to the
administration of morphine sulfate? - CORRECT ✔✔✔✔✔ Rate of respirations

A client receives a prescription for an oral opioid analgesic for post-operative pain.
Which adverse effect should the practical nurse (PN) monitor for in the client? -
CORRECT ✔✔✔✔✔ Constipation

The healthcare provider prescribes celecoxib (Celebrex), a nonsteroidal
antiinflammatory drug (NSAID), for a client with osteoarthritis. Which finding in the
client's history should the practical nurse (PN) report? - CORRECT ✔✔✔✔✔ Peptic
ulcer disease

The healthcare provider prescribes an antibiotic for a male adolescent with an upper
respiratory tract infection, who asks the practical nurse (PN) how long the prescribed
antibiotics should be taken. What information should the PN provide? - CORRECT
✔✔✔✔✔ Continue the medication until all of the prescription is taken

The practical nurse asks a male client who came to the clinic with an upper respiratory
infection if he has any drug allergies. The client cannot remember ir he does or if he
ever received penicillin. After administering the injection penicillin, the PN tells the client
to stay for 30 minutes of observation. Which finding should the PN identify that is
indicative of a reaction to the medication? - CORRECT ✔✔✔✔✔ Rash, itching, and
hives

A client's tissue culture results indicate the wound is infected with methicillin-resistant
Staphylococcus aureus (MRSA). What action should the practical nurse (PN) implement
first? - CORRECT ✔✔✔✔✔ implement contact isolation precautions

A client who has been taking phenazopyridine (Pyridium) for symptoms of urethritis and
cystitis comes to the clinic because her urine is reddish-orange. Which question should
the practical nurse ask to determine if the medication has been effective? - CORRECT
✔✔✔✔✔ Have you had any relief from urinary pain, burning, or urgency?

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