ANSWERS
1. Describe how VPA affects the levels of warfarin in the body.
VPA has no effect on warfarin levels.
VPA only affects warfarin in patients with liver disease.
VPA increases warfarin levels, which can enhance its anticoagulant
effects.
VPA decreases warfarin levels, reducing its effectiveness.
2. Which is NOT an interaction w/VPA
aspirin
lisinopril
warfarin
lamotrigine
3. Describe the role of SGA and Lamotrigine in the treatment of acute
depressive episodes in bipolar disorder.
SGA is only used for manic episodes, while Lamotrigine is ineffective.
Lamotrigine is a second-line treatment for depressive episodes.
Both medications are primarily used for anxiety disorders.
SGA and Lamotrigine are used as first-line treatments to stabilize
mood and alleviate depressive symptoms in bipolar disorder.
4. If a patient is being treated with venlafaxine and wishes to discontinue the
,medication, what steps should a healthcare provider take to minimize the
, risk of discontinuation syndrome?
Immediately stop the medication to prevent side effects.
Switch to a different antidepressant without tapering.
Gradually taper the dosage of venlafaxine over a period of time.
Increase the dosage of venlafaxine before discontinuation.
5. Describe the role of Bupropion in the treatment of seasonal depression.
Bupropion is an antipsychotic medication.
Bupropion is a mood stabilizer used for bipolar disorder.
Bupropion is primarily used for anxiety disorders.
Bupropion is an antidepressant that is effective in treating
seasonal affective disorder by helping to regulate mood.
6. The quality assurance committee at the hospital wants pharmacists to
screen for psychiatric disorders in primary care clinics. The
recommendation is to screen for major depressive disorder (MDD) with the
PHQ-9 and generalized anxiety disorder (GAD) with the GAD-7. Committee
members are familiar with the PHQ-9 but ask for additional information on
the GAD-7. Which statement best describes the GAD7?
Use is limited to clinical trials
It is sensitive for GAD and MDD
Lower scores indicate greater severity
It is a patient self-rated scale
7. What type of study design is depicted in the diagram?
, Prospective cohort study
Case-control study
Case study
Retrospective cohort
Randomized control trial
8. What is the definition of attrition bias in research studies?
The study fails to account for external variables affecting the results.
All participants complete the study without any dropouts.
Participants are randomly assigned to different groups in a study.
Certain participants are more likely to drop out of the study than
others, leading to a final sample that differs from the initial.
9. To calculate an odds ratio:
ad/bc
ac/bd
None of the above
ab/cd
10. If a patient is switched from Trintellix to a medication with a shorter half life,
what might be a potential concern regarding discontinuation syndrome?
Decreased risk of discontinuation syndrome.
Increased risk of discontinuation syndrome.
No change in discontinuation risk.