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Secure CSE Exam – 2025/2026 | 100+ Verified Questions with Answers | Critical Care, Ventilator Management, Neonatal & Emergency Protocols

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This advanced clinical simulation exam prep document includes 100+ structured and high-yield questions with verified answers, specifically curated for students preparing for the Secure Clinical Simulation Exam (CSE) in respiratory therapy. The content is designed to help learners master decision-making, ventilator management, diagnostics, and neonatal protocols, in alignment with NBRC (National Board for Respiratory Care) exam standards for 2025/2026. Topics include: – A-VOCP-U hierarchy for clinical prioritization – Airway emergencies, oxygenation vs ventilation decisions – Ventilator alarm troubleshooting (high/low pressure, disconnects, PEEP changes) – Neonatal ventilation (PC-SIMV, initial settings, bubble CPAP, FiO2 titration) – Weaning criteria and SBT termination indicators – Cardiopulmonary pharmacology and emergency management (e.g., ACLS drugs, asthma control meds) – Trauma care, chest injuries, and pulmonary embolism diagnostics This document is best suited for: – Respiratory Therapy students (AS/BS programs) – NBRC CSE and TMC exam candidates – ICU, NICU, and emergency care trainees – Medical professionals reviewing critical care protocols The guide presents real-exam logic, step-by-step clinical reasoning, and best practices to enhance confidence and clinical judgment for both written and simulation-based testing. Keywords: CSE exam prep, respiratory therapy, ventilator management, neonatal ventilation, ABG interpretation, NBRC exam, SBT criteria, oxygen titration, high flow devices, bubble CPAP, ventilator alarms, trauma assessment, ACLS medications, lung pathologies, clinical decision making

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Secure CSE 2025/2026 Exam Questions
and Answers | A+ Score Assured



What does A-VOCP-U stand for (in order of priority) - 🧠 ANSWER ✔✔-

airway

-ventilation

-oxygenation

-circulation

-perfusion

-underlying issue / disease process / symptoms

Airway compromise will trump ____________________________ - without

an airway, we __________________ - 🧠 ANSWER ✔✔-every issue except

cardiac arrest

-cannot ventilate

, What drug should I never choose on the CSE - 🧠 ANSWER

✔✔MUCOMYST (N-ACETYLCYSTEINE)


When choosing items in the IG and DM section, what order do you go

about it - 🧠 ANSWER ✔✔-Least invasive to most invasive




1. Visual assessment, then

2. Hands on physical assessment, then

3. Non-invasive diagnostic tests, then

4. Invasive diagnostic tests

IF YOU NEVER HEARD OF SOMETHING OR DO NOT KNOW WHAT IT

IS, THEN _______________ - 🧠 ANSWER ✔✔DO NOT CHOOSE IT!


When given the option to initiate or change FiO2, choose to - 🧠 ANSWER

✔✔titrate O2


If SpO2 is 86% or above... - 🧠 ANSWER ✔✔choose a low flow O2 device


If SpO2 is 85% and below, choose a _____________________, except for

___________________ - 🧠 ANSWER ✔✔-high flow O2 device

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