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PRITE Part II – 2025/2026 | 250+ Verified Exam Questions & Answers | Neuro, Psychotherapy, Ethics, Sleep Disorders

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This document provides a fully updated, in-depth PRITE Part II exam preparation resource for the 2025/2026 academic year, featuring 250+ high-yield multiple-choice questions with correct answers. Specifically tailored for psychiatry residents in their third and fourth years (PGY3–PGY4), this guide is ideal for advanced learners aiming to master the second half of the PRITE exam—especially those from institutions such as Yale University, or similar top-tier programs. The questions cover advanced clinical reasoning, psychiatric diagnostics, psychopharmacology, neuropsychiatry, and legal/ethical challenges, all aligned with current standards and PRITE blueprints. Topics include: Psychopharmacology: lithium, antipsychotics, antidepressants, side effect management Neurocognitive and developmental disorders: Parkinson’s, Alzheimer’s, ADHD, autism Psychiatric emergencies and inpatient management Ethical dilemmas, informed consent, surrogate decision-making Sleep disorders, Kleine-Levin syndrome, narcolepsy, REM sleep behavior disorder Defense mechanisms and developmental theories (Freud, Erikson, Piaget) Therapeutic modalities: CBT, DBT, psychoanalysis, psychodynamic therapy Genetic & biological psychiatry: neuropeptides, neurotoxins, neurotransmitter pathways Marked with clear annotations and exam-repetition tags (e.g. “”), this document is especially useful for: Psychiatry residents preparing for the PRITE Part II Clinical psychology and neuropsychology students Medical students with a psychiatry concentration Faculty compiling practice material for PRITE review courses Each answer is accurate, concise, and contextually explained to reinforce critical test-taking strategies. The document also integrates real-case scenarios and up-to-date references from neurobiology and psychodynamic literature, making it suitable for both formative assessment and high-stakes board exam simulation. Keywords: PRITE Part II, psychiatry exam 2025, psychopharmacology, neurocognitive disorders, ethical psychiatry, bipolar disorder, lithium side effects, CBT, DBT, developmental psychiatry, ADHD, autism, narcolepsy, REM sleep, inpatient psychiatry, medical decision-making, neurotransmitters, Yale psychiatry, psychiatric emergencies, exam prep

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Prite Part II 2025/2026 Exam Questions
with 100% Correct Answers | Latest
Update


Which of the following methodologies is used to examine inter-generational

transfer of a disorder phenotype? - 🧠ANSWER ✔✔Segregation analysis


Ainsworth introduced the strange situation experiment to evaluate which of

the following? - 🧠ANSWER ✔✔Attachment between a parent and child


Localized amnesia is best described as an inability to recall: - 🧠ANSWER

✔✔Any events within a given period of time


A 32-year old patient has episodes of irresistible sleepiness and falls

asleep while driving. The patient reports experiencing episodes of paralysis

and hallucinations upon awakening. These symptoms are best explained

by a deficiency in which of the following. - 🧠ANSWER ✔✔Orexin

,A patient presents with a three week history of markedly depressed mood

insomnia and weight loss. Family members report that patient has been

despondent refuses to engage in usually enjoyable activities and spends

most of the day in bed. Although patient feels mood improves somewhat in

the evenings family reports that patient takes no pleasure or interest

engaging with grandchildren when they visit for dinner. On interview the

patient reports guilty ruminations and feelings of hopelessness. A diagnosis

of MDD is made by the psychiatrist. Which DSM specifier would be applied

to this diagnosis? - 🧠ANSWER ✔✔Melancholic features


A patient with metabolic syndrome and schizophrenia exhibits positive

symptom relief and improved functioning on haloperidol. After two years on

a therapeutic dose the patient starts to develop new-onset lip smacking that

affects their ability to eat. Adding which of the following medications would

be most likely to reduce these adverse effects? - 🧠ANSWER

✔✔Valbenazine


A 25-year-old woman presents with concerns about difficulty engaging in

sexual intercourse. She appears embarrassed and has difficulty providing

any additional information about her symptoms stating "I am extremely

uncomfortable talking about this." She experienced "vaginal spasms"

,during her last sexual encounter and she consequently feels anxious when

considering having sex. She has become avoidant and dismissive of sexual

encounters. She has had a normal gynecologic examination without

discomfort and her gynecologist referred her to the psychiatrist. Which of

the following is the most likely diagnosis? - 🧠ANSWER ✔✔Genito-pelvic

pain/penetration disorder


Biofeedback targets which of the following for - 🧠ANSWER ✔✔Involuntary

responses of the autonomic nervous system

Which of the following Medicare components provides prescription drug

coverage? - 🧠ANSWER ✔✔Medicare Part D


What is the leading cause of premature death in patients with

schizophrenia? - 🧠ANSWER ✔✔Cardiovascular disease


Which of the following substances is most likely to increase lithium levels? -

🧠ANSWER ✔✔Hydrochlorothiazide


What is the most common form of sequence variation in the genome? -

🧠ANSWER ✔✔Single nucleotide polymorphisms




3
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, Which potentially fatal condition can be caused by mutations in the

branched-chain alpha-keto acid dehydrogenase complex? - 🧠ANSWER

✔✔Maple Syrup Urine Disease


In accordance with the 21st Century Cures Act physicians may withhold

access of psychiatric notes in which of the following cases? - 🧠ANSWER

✔✔The note includes sensitive information revealed in a psychotherapy

session

Which of the following tests allows unbiased detection leading to

identification of novel transcripts? - 🧠ANSWER ✔✔RNA-sequencing


Which of the following cognitive functions is most likely to be preserved

with normal aging? - 🧠ANSWER ✔✔Expressive language


Under the HIPAA Privacy Rule, a patient has the right to: - 🧠ANSWER

✔✔Obtain most disclosures of medical history upon request


During administration of performance tasks on standardized intelligence

testing which of the following areas shows the greatest increase in

metabolic activity - 🧠ANSWER ✔✔Right parietal lobe
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