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NR567 Final Study Guide: Key Medications and Treatments Questions with Correct Verified Answers (Latest 2026/2027)

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This document provides the full collection of NR 567 Advanced Pharmacology final review exam questions along with verified correct answers for the 2025/2026 academic year. It covers major pharmacological topics including drug classifications, mechanisms of action, adverse effects, dosage guidelines, and clinical applications. Perfect for Nurse Practitioner students preparing for exams or seeking a concise, accurate review of advanced pharmacology concepts. What is an example of a Nonsteroidal Anti-inflammatory Drug (NSAID) used for allergic conjunctivitis? - ANS Ketorolac. What is the use of Glucocorticoids in treating allergic conjunctivitis? - ANS Reserved for short-term use in severe or refractory cases. What is the mechanism of action of β-Adrenergic Blockers in treating open angle glaucoma? - ANS They decrease aqueous humor production. What is the effect of α2-Adrenergic Agonists on intraocular pressure (IOP)? - ANS They decrease aqueous humor production and increase aqueous humor outflow. What is the first-line treatment for glaucoma due to its high efficacy? - ANS Prostaglandin Inhibitors, such as Latanoprost. What is the mechanism of action of Cholinesterase Inhibitors in glaucoma treatment? - ANS They increase aqueous humor outflow by inhibiting cholinesterase. What are the two examples of Carbonic Anhydrase Inhibitors? - ANS Dorzolamide and Acetazolamide.

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1
NR567 Final




NR567 Final Study Guide: Key Medications
and Treatments Questions with Correct
Verified Answers (Latest 2026/2027)



What is an example of a Nonsteroidal Anti-inflammatory Drug (NSAID)
used for allergic conjunctivitis? - ANS ✓Ketorolac.


What is the use of Glucocorticoids in treating allergic conjunctivitis? - ANS
✓Reserved for short-term use in severe or refractory cases.


What is the mechanism of action of β-Adrenergic Blockers in treating open-
angle glaucoma? - ANS ✓They decrease aqueous humor production.


What is the effect of α2-Adrenergic Agonists on intraocular pressure (IOP)?
- ANS ✓They decrease aqueous humor production and increase aqueous
humor outflow.


What is the first-line treatment for glaucoma due to its high efficacy? - ANS
✓Prostaglandin Inhibitors, such as Latanoprost.


What is the mechanism of action of Cholinesterase Inhibitors in glaucoma
treatment? - ANS ✓They increase aqueous humor outflow by inhibiting
cholinesterase.


What are the two examples of Carbonic Anhydrase Inhibitors? - ANS
✓Dorzolamide and Acetazolamide.


NR567 Final

, 2
NR567 Final




What caution should be taken with Carbonic Anhydrase Inhibitors in sulfa-
allergic patients? - ANS ✓They may trigger allergic reactions due to
sulfonamide groups.


Which glaucoma medications are generally considered safe for sulfa-
allergic patients? - ANS ✓Prostaglandin Analogues and Beta-Blockers.



What is the mechanism of action of Prostaglandin Analogues? - ANS ✓They
increase aqueous humor outflow.


What is the example of a Beta-Blocker used for glaucoma? - ANS ✓Timolol.


What are examples of Alpha Adrenergic Agonists used in glaucoma
treatment? - ANS ✓Brimonidine and Apraclonidine.


What is the mechanism of action for Alpha Adrenergic Agonists in
glaucoma? - ANS ✓They decrease aqueous humor production and may
increase outflow.


Are Alpha Adrenergic Agonists safe for patients with sulfa allergies? - ANS
✓Yes, they are generally safe in patients with sulfa allergies.


What should be avoided in glaucoma patients with a sulfa allergy? - ANS
✓Carbonic anhydrase inhibitors, especially oral formulations.




NR567 Final

, 3
NR567 Final


What are first-line alternatives for glaucoma treatment in patients with
sulfa allergies? - ANS ✓Prostaglandin analogs, beta-blockers, and alpha
agonists.


What is the most common pathogen causing Acute Otitis Media (AOM)? -
ANS ✓Haemophilus influenzae (nontypeable) at 56%.


What syndrome is frequently associated with Haemophilus influenzae in
AOM? - ANS ✓Conjunctivitis-otitis syndrome.


What percentage of AOM cases are caused by Moraxella catarrhalis? - ANS
✓22%.



What is a notable characteristic of Moraxella catarrhalis? - ANS ✓It
produces β-lactamase.


What is the historical significance of Streptococcus pneumoniae in AOM? -
ANS ✓It was historically the most common cause but is now less frequent
due to vaccination.


What is the goal of treatment for Acute Otitis Externa (AOE)? - ANS ✓To
eradicate infection and relieve pain.


What is the first-line treatment for uncomplicated AOE? - ANS ✓Topical
therapy.




NR567 Final

, 4
NR567 Final


What are some topical options for treating AOE? - ANS ✓Acetic acid 2%
solution, alcohol + acetic acid, fluoroquinolones (e.g., ciprofloxacin), and
neomycin/polymyxin B/hydrocortisone combination.


What oral antibiotic is indicated for adults with AOE when infection
spreads? - ANS ✓Oral ciprofloxacin.


What oral antibiotic is recommended for children with AOE? - ANS
✓Cephalexin (Keflex).



What are common side effects of Montelukast? - ANS ✓Mood changes,
depression, suicidality, and rare Churg-Strauss syndrome.


What side effects are associated with Zafirlukast? - ANS ✓Headache,
gastrointestinal disturbances, arthralgia, myalgia, depression, and rare liver
injury.


What neuropsychiatric effects can Zileuton cause? - ANS ✓Depression,
anxiety, agitation, abnormal dreams, hallucinations, and suicidality.


What triggers Seasonal Allergic Rhinitis (Hay Fever)? - ANS ✓Outdoor
allergens such as pollen from weeds, grasses, trees, and fungi.


What is perennial allergic rhinitis? - ANS ✓A year-round condition
triggered by indoor allergens such as house dust mites and pet dander.


What are the main drug categories used for treating allergic rhinitis? - ANS
✓1. Intranasal glucocorticoids 2. Antihistamines 3. Intranasal


NR567 Final

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