NUR 378
NUR 378 Exam 3 Pharmacology |
Questions & Answers| Grade A |
100% Correct |Latest (2025/ 2026)
Dopamine is a ____-adrenergic - ANS ✓beta
Dopamine is a ______ catecholamine - ANS ✓naturally occurring
Dopamine at low dosages: - ANS ✓dilates blood vessels of:
Brain
Heart
Kidney
Mesentery
Dopamine at low dosages acts on... - ANS ✓dopaminergic receptors
Dopamine at moderate dosages: - ANS ✓improves cardiac contractility and output
Dopamine at moderate dosages acts on... - ANS ✓beta1-receptors
Dopamine at high dosages: - ANS ✓causes vasoconstriction
Dopamine at high dosages acts on... - ANS ✓alpha1-receptors
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When a beta1-adrenergic receptor is stimulated by an adrenergic drug, what three
things can result? - ANS ✓1. Positive inotropic effect
2. Positive chronotropic effect
3. Positive dromotropic effect
Inotropic - ANS ✓strength of contraction
Positive inotropic effect example - ANS ✓increase in the force of contraction
Chronotropic - ANS ✓rate of contraction
Positive chronotropic effect example - ANS ✓increase heart rate
Dromotropic - ANS ✓heart conductivity
Positive dromotropic effect example - ANS ✓increase in conduction of cardiac electrical
nerve impulses through AV node
Epinephrine is an _____ catecholamine - ANS ✓endogenous vasoactive
There are also beta1-receptors at the ____ that cause _____ when stimulated - ANS
✓kidneys; an increase in renin secretion
MOA epinephrine - ANS ✓acts directly on alpha- and beta-adrenergic receptors at
tissues innervated by the SNS
Physiologic response to epinephrine is... - ANS ✓dose related
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Epinephrine at low dosages: - ANS ✓positive inotropic and chronotropic effects
Epinephrine at low dosages acts on... - ANS ✓beta1-adrenergic receptors
Epinephrine at high dosages: - ANS ✓causes vasoconstriction and elevates blood
pressure
Epinephrine at high dosages acts on... - ANS ✓alpha-adrenergic receptors
Epinephrine is a _____ adrenergic - ANS ✓alpha- and beta-
MOA phenylephrine - ANS ✓stimulates alpha-adrenergic receptors
Adrenergic-blocking (antagonist) drugs - ANS ✓phentolamine
Metoprolol
MOA adrenergic-blocking drugs - ANS ✓bind to adrenergic receptors and inhibit or
block SNS stimulation
Adrenergic-blockers are also called _____ because _____ - ANS ✓sympatholytics; they lyse
or inhibit SNS stimulation
Types of adrenergic-blockers - ANS ✓alpha blockers
Beta blockers
Alpha blocker drug - ANS ✓phentolamine
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MOA phentolamine - ANS ✓block alpha1-adrenergic receptors stopping SNS stimulation
Alpha blockers have a greater affinity for ______ than ____ which allows alpha blockers to
_____ - ANS ✓alpha-adrenergic receptors; norepinephrine; chemically displace
norepinephrine
Beta blocker drug - ANS ✓metoprolol
MOA metoprolol - ANS ✓blocks beta1-adrenergic receptors stopping SNS stimulation
Cholinergic drugs are similar to or mimic _____ which is _____ - ANS ✓PNS
neurotransmitter; acetylcholine
Cholinergic drugs can stimulate _____ either _____ or ____ - ANS ✓cholinergic receptors;
directly; indirectly
Direct-acting cholinergic - ANS ✓bethanechol
MOA bethanechol - ANS ✓increases bladder and GI tract tone and motility
Bethanechol acts on... - ANS ✓detrusor muscle of bladder
Smooth muscle @ GI tract
Cholinergic drugs primarily affect ____ at recommended dosages - ANS ✓muscarinic
receptors
At high dosages, cholinergic drugs can also stimulate _____ - ANS ✓nicotinic receptors
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