Berne and Levy Physiology 7th Edition KoeppenTest Bank
jh jh jh jh jh jh jh
, Koeppen: Berne and Levy Physiology, 7th Edition
jh jh jh jh jh jh
Chapter 01: Principles of Cell h
j jh jh h
j
FunctionTest Bank
jh jh
Multiple Choice jh
1. The subcellular structure that degrades proteins is called the:
jh jh jh jh jh jh jh jh
A. Tight junction jh
B. Mitochondria
C. Lysosome
D. Plasma membrane jh
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
data are obtained:
jh jh jh
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
markedly reduced. According to this information, which of the followingmechanisms is
jh jh jh jh jh jh jh jh jh jh jh
probably responsible for the transport of the amino acid into the cell?
jh jh jh jh jh jh jh jh jh jh jh jh
A. Passive diffusion through the lipid bilayer jh jh jh jh jh
B. Uniporter
C. Transport ATPase jh
D. Na+ symporter jh
E. Na+antiporter
ANS: D
jh j h
3. Amembrane permeable byonly Na+ separatestwo compartments containing
jh jh jh jh jh jh
Na2SO4,shown as follows:
jh jh jh
,Electrodes are placed in both compartments, and a voltage is applied (that of
jh jh jh jh jh jh jh jh jh jh jh jh
compartment A is held at 0 mV). What voltage applied to compartment B would resultin
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
no net movement of Na+ across the membrane separating the compartments?
jh jh jh jh jh jh jh jh jh jh jh
–60 mV
A. jh
–30 mV
B. jh
C.
0 mV jh
D. +30 mV jh
E. +60mV
ANS: E j h j h
4. Therestingmembrane potentNial oRf a Ic ellGis –B
jh 85.m
CV. Theintracellularand jh jh jh jh j h j h jh jh
extracellular concentrations ofUseveral
jh
SN ions are indicated in the following table, as
jh jh jh
h
j h
j
jh jh jh jh jh jh jh jh
is the calculated
jh jh jh
Nernst equilibrium potential (Ei) for each of these ions:
jh jh jh jh jh jh jh jh
Ion Concentration Concentration Ei
Inside Cell jh Outside Cell jh
+
Na 12 mEq/L jh 145 mEq/L jh 66 mV jh
K+ 150 mEq/L jh 4 mEq/L
jh –96 mV jh
Cl– 30 mEq/L jh 105 mEq/L jh –33 mV jh
Ca++ 0.0001 mmol/dL jh 1 mmol/dL
jh 122 mV jh
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
jh jh jh jh jh jh jh jh jh jh jh jh jh
membrane is the greatest for which ion?
jh jh jh jh jh jh jh
A. Na+
B. K+
C. Cl–
D. Ca++
AN j h
S:
B
5. A cell contains the following membrane transporters:
jh jh jh jh jh jh
Na+channelK+channel
jh jh
Na+,K+-ATPase
jh
The resting membrane voltage of the cell is –80 mV, and the intracellular and
jh jh jh jh jh jh jh jh jh jh jh jh jh
, extracellular ion concentrations are as follows:
jh jh jh jh jh
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L jh 145 mEq/L jh
K+ 120 mEq/L jh 4 mEq/L jh
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug on the
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
following parameters?
jh jh
Intracellular [Na+] jh Intracellular [K+] jh Cell Volume
jh Membrane Voltage jh
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
jh
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by a
jh jh jh jh jh jh jh jh jh jh jh jh
glycosylphosphatidylinositol (GPI) anchor?
jh jh jh
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting
jh jh jh jh jh jh jh jh
j h
jh jh jh jh jh
membrane potential is –60 mV (cell interior negative). The intracellular and
jh jh jh jh jh jh jh jh jh jh jh
extracellular concentrations for these ions, as well as the calculated Nernst
jh jh jh jh jh jh jh jh jh jh jh
potentials, are listed as follows:
jh jh jh jh jh
jh jh jh jh jh jh jh
, Koeppen: Berne and Levy Physiology, 7th Edition
jh jh jh jh jh jh
Chapter 01: Principles of Cell h
j jh jh h
j
FunctionTest Bank
jh jh
Multiple Choice jh
1. The subcellular structure that degrades proteins is called the:
jh jh jh jh jh jh jh jh
A. Tight junction jh
B. Mitochondria
C. Lysosome
D. Plasma membrane jh
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The following
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
data are obtained:
jh jh jh
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents the
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
cell from making adenosine triphosphate (ATP), the uptake of amino acid into the cell is
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
markedly reduced. According to this information, which of the followingmechanisms is
jh jh jh jh jh jh jh jh jh jh jh
probably responsible for the transport of the amino acid into the cell?
jh jh jh jh jh jh jh jh jh jh jh jh
A. Passive diffusion through the lipid bilayer jh jh jh jh jh
B. Uniporter
C. Transport ATPase jh
D. Na+ symporter jh
E. Na+antiporter
ANS: D
jh j h
3. Amembrane permeable byonly Na+ separatestwo compartments containing
jh jh jh jh jh jh
Na2SO4,shown as follows:
jh jh jh
,Electrodes are placed in both compartments, and a voltage is applied (that of
jh jh jh jh jh jh jh jh jh jh jh jh
compartment A is held at 0 mV). What voltage applied to compartment B would resultin
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
no net movement of Na+ across the membrane separating the compartments?
jh jh jh jh jh jh jh jh jh jh jh
–60 mV
A. jh
–30 mV
B. jh
C.
0 mV jh
D. +30 mV jh
E. +60mV
ANS: E j h j h
4. Therestingmembrane potentNial oRf a Ic ellGis –B
jh 85.m
CV. Theintracellularand jh jh jh jh j h j h jh jh
extracellular concentrations ofUseveral
jh
SN ions are indicated in the following table, as
jh jh jh
h
j h
j
jh jh jh jh jh jh jh jh
is the calculated
jh jh jh
Nernst equilibrium potential (Ei) for each of these ions:
jh jh jh jh jh jh jh jh
Ion Concentration Concentration Ei
Inside Cell jh Outside Cell jh
+
Na 12 mEq/L jh 145 mEq/L jh 66 mV jh
K+ 150 mEq/L jh 4 mEq/L
jh –96 mV jh
Cl– 30 mEq/L jh 105 mEq/L jh –33 mV jh
Ca++ 0.0001 mmol/dL jh 1 mmol/dL
jh 122 mV jh
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
jh jh jh jh jh jh jh jh jh jh jh jh jh
membrane is the greatest for which ion?
jh jh jh jh jh jh jh
A. Na+
B. K+
C. Cl–
D. Ca++
AN j h
S:
B
5. A cell contains the following membrane transporters:
jh jh jh jh jh jh
Na+channelK+channel
jh jh
Na+,K+-ATPase
jh
The resting membrane voltage of the cell is –80 mV, and the intracellular and
jh jh jh jh jh jh jh jh jh jh jh jh jh
, extracellular ion concentrations are as follows:
jh jh jh jh jh
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L jh 145 mEq/L jh
K+ 120 mEq/L jh 4 mEq/L jh
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug on the
jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh jh
following parameters?
jh jh
Intracellular [Na+] jh Intracellular [K+] jh Cell Volume
jh Membrane Voltage jh
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
jh
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by a
jh jh jh jh jh jh jh jh jh jh jh jh
glycosylphosphatidylinositol (GPI) anchor?
jh jh jh
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting
jh jh jh jh jh jh jh jh
j h
jh jh jh jh jh
membrane potential is –60 mV (cell interior negative). The intracellular and
jh jh jh jh jh jh jh jh jh jh jh
extracellular concentrations for these ions, as well as the calculated Nernst
jh jh jh jh jh jh jh jh jh jh jh
potentials, are listed as follows:
jh jh jh jh jh
