ASCP Board of Certification MLT exam
Review 2024/2025 Exam Questions and
Detailed Answers | Get it 100% Correct
Answers
Nephelometry is based on the principle of: - 🧠ANSWER ✔✔Turbidity
resulting from specific antigen-coated latex particles agglutinated by
corresponding antibody
Which of the following can cause hemolysis and perhaps result in
recollection of the specimen? - 🧠ANSWER ✔✔Pushing the plunger of a
syringe when transferring blood into vacuum tubes.
A manual white blood cell count was performed by the hematology
technologist. The cell counts for both sides were 99 and 164, respectively.
All nine large squares were counted on each side. The dilution for this kit
was pre-measured at 1:100. What should the technologist report as the
white cell count? - 🧠ANSWER ✔✔Cannot report
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,When comparing the white cell counts from one side of the hemacytometer
to the other, there is not good duplication. Cell counts from opposite sides
of the hemacytometer (within the same patient sample) that are greater
than 10% of one another are considered discrepant and should not be used
to calculate reportable results. This particular count should not be used to
report patient results.
The RBC inclusions shown in the photograph represent which of the
following? - 🧠ANSWER ✔✔Howell-Jolly bodies
Howell-Jolly bodies are usually single, round, and tend to be positioned at
the periphery of the red blood cell. These inclusions are rarely found on a
routine peripheral blood smear, as they are usually removed by a
functioning spleen. Howell-Jolly bodies appear in megaloblastic anemias
and after splenectomy.
Which of the following tests would be employed in order to detect neural
tube defects? - 🧠ANSWER ✔✔Alpha fetoprotein
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2
,Alpha-fetoprotein is a protein measured in pregnant women, using maternal
blood or amniotic fluid, as a screening test for a subset developmental
abnormalities: it is principally increased in open neural tube defects and
decreased in Down syndrome.
A patient has the following serum results:
Na = 130 mEq/LK = 4.9 mEq/LCl = 107 mEq/LGlucose = 300 mg/dLBUN =
18 mg/dLCreatinine = 1.1 mg/dL
Which osmolality result is consistent with these results?. - 🧠ANSWER
✔✔281 mosmol/kg
Osmolality = 2 x Na + [Glucose (mg/dL) / 20] + [BUN (mg/dL)/ 3]
A liquid ion-exchange membrane electrode using the antibiotic valinomycin
is MOST selective for: - 🧠ANSWER ✔✔Potassium
The valinomycin membrane electrode is most selective for potassium as
opposed to sodium, glucose, or chloride which utilize different membranes
for their respective electrodes. Valinomycin, which is neutral in charge, has
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY STATEMENT.
ALL RIGHTS RESERVED
3
, been incorporated into organic liquid membranes resulting in a sensor with
a very high selectivity for potassium.
What should safety management start with in order to ensure clarity and
consistency? - 🧠ANSWER ✔✔A written safety policy
Which of the following statements about high-frequency antigens is
correct? - 🧠ANSWER ✔✔High-frequency antigens are common, but it is
difficult to identify their corresponding antibodies.
An adult's plasma cortisol of 22 µg/dL at 8:00 a.m. and 10 µg/dL at 4:00
p.m. would be: - 🧠ANSWER ✔✔Found in a healthy individual
Normal levels: 5-23 µg/dL at 8:00 a.m.
3-16 µg/dL at 4:00 p.m.
<50% of 8:00 a.m. values at 8:00 p.m.
A peripheral smear demonstrates a population of red cells that are mostly 5
- 5.5 µm in diameter. The CBC data shows RDW of 13% (reference range
11.5-14.5%). Which of the following morphologies is consistent with these
findings? - 🧠ANSWER ✔✔Microcytosis, low variation of cell volume
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY STATEMENT.
ALL RIGHTS RESERVED
4
Review 2024/2025 Exam Questions and
Detailed Answers | Get it 100% Correct
Answers
Nephelometry is based on the principle of: - 🧠ANSWER ✔✔Turbidity
resulting from specific antigen-coated latex particles agglutinated by
corresponding antibody
Which of the following can cause hemolysis and perhaps result in
recollection of the specimen? - 🧠ANSWER ✔✔Pushing the plunger of a
syringe when transferring blood into vacuum tubes.
A manual white blood cell count was performed by the hematology
technologist. The cell counts for both sides were 99 and 164, respectively.
All nine large squares were counted on each side. The dilution for this kit
was pre-measured at 1:100. What should the technologist report as the
white cell count? - 🧠ANSWER ✔✔Cannot report
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY STATEMENT.
ALL RIGHTS RESERVED
1
,When comparing the white cell counts from one side of the hemacytometer
to the other, there is not good duplication. Cell counts from opposite sides
of the hemacytometer (within the same patient sample) that are greater
than 10% of one another are considered discrepant and should not be used
to calculate reportable results. This particular count should not be used to
report patient results.
The RBC inclusions shown in the photograph represent which of the
following? - 🧠ANSWER ✔✔Howell-Jolly bodies
Howell-Jolly bodies are usually single, round, and tend to be positioned at
the periphery of the red blood cell. These inclusions are rarely found on a
routine peripheral blood smear, as they are usually removed by a
functioning spleen. Howell-Jolly bodies appear in megaloblastic anemias
and after splenectomy.
Which of the following tests would be employed in order to detect neural
tube defects? - 🧠ANSWER ✔✔Alpha fetoprotein
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY STATEMENT.
ALL RIGHTS RESERVED
2
,Alpha-fetoprotein is a protein measured in pregnant women, using maternal
blood or amniotic fluid, as a screening test for a subset developmental
abnormalities: it is principally increased in open neural tube defects and
decreased in Down syndrome.
A patient has the following serum results:
Na = 130 mEq/LK = 4.9 mEq/LCl = 107 mEq/LGlucose = 300 mg/dLBUN =
18 mg/dLCreatinine = 1.1 mg/dL
Which osmolality result is consistent with these results?. - 🧠ANSWER
✔✔281 mosmol/kg
Osmolality = 2 x Na + [Glucose (mg/dL) / 20] + [BUN (mg/dL)/ 3]
A liquid ion-exchange membrane electrode using the antibiotic valinomycin
is MOST selective for: - 🧠ANSWER ✔✔Potassium
The valinomycin membrane electrode is most selective for potassium as
opposed to sodium, glucose, or chloride which utilize different membranes
for their respective electrodes. Valinomycin, which is neutral in charge, has
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY STATEMENT.
ALL RIGHTS RESERVED
3
, been incorporated into organic liquid membranes resulting in a sensor with
a very high selectivity for potassium.
What should safety management start with in order to ensure clarity and
consistency? - 🧠ANSWER ✔✔A written safety policy
Which of the following statements about high-frequency antigens is
correct? - 🧠ANSWER ✔✔High-frequency antigens are common, but it is
difficult to identify their corresponding antibodies.
An adult's plasma cortisol of 22 µg/dL at 8:00 a.m. and 10 µg/dL at 4:00
p.m. would be: - 🧠ANSWER ✔✔Found in a healthy individual
Normal levels: 5-23 µg/dL at 8:00 a.m.
3-16 µg/dL at 4:00 p.m.
<50% of 8:00 a.m. values at 8:00 p.m.
A peripheral smear demonstrates a population of red cells that are mostly 5
- 5.5 µm in diameter. The CBC data shows RDW of 13% (reference range
11.5-14.5%). Which of the following morphologies is consistent with these
findings? - 🧠ANSWER ✔✔Microcytosis, low variation of cell volume
COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY STATEMENT.
ALL RIGHTS RESERVED
4
