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TEST BANK - FOCUS ON NURSING PHARMACOLOGY 9TH EDITION BY AMY KARCH CHAPTER 1-59 EXAM 2025 LATEST NEWEST UPDATE WITH ACTUAL QUESTIONS AND DETAILED VERIFIED ANSWERS WITH RATIONALES (100% CORRECT) //BRAND NEW!! /ALREADY GRADED A+ WITH GUARANTEED SUCCESS A

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TEST BANK - FOCUS ON NURSING PHARMACOLOGY 9TH EDITION BY AMY KARCH CHAPTER 1-59 EXAM 2025 LATEST NEWEST UPDATE WITH ACTUAL QUESTIONS AND DETAILED VERIFIED ANSWERS WITH RATIONALES (100% CORRECT) //BRAND NEW!! /ALREADY GRADED A+ WITH GUARANTEED SUCCESS AFTER DOWNLOAD (ALL YOU NEED TO PASS YOUR EXAMS In what patient is propranolol (Inderal) contraindicated? 26-year-old man with viral myocarditis 45-year-old woman with heart failure who suffered a myocardial infarction 42-year-old man with hypertension 65-year-old woman with persistent migraines Ans: B Feedback: Beta-adrenergic blocking agents are contraindicated in patients with bradycardia, heart failure, and heart block. The drug would not be contraindicated in the other patients. 18. What assessment finding indicates to the nurse that timolol (Timoptic) has been effective? The patient’s blood pressure increases. The patient’s intraocular pressure is reduced. The patient’s pulse is reduced. The patient’s angina is reduced. Ans: B Feedback: Timolol and carteolol are available in an ophthalmic form of the drug for reduction of intraocular pressure in patients with open-angle glaucoma. A decrease in intraocular pressure would indicate it has been effective. Timolol can also be used to treat hypertension but an increase in blood pressure would indicate the drug was not effective. Reduced pulse rate and reduced angina would not be related to this drug, especially if it was given in ophthalmic form when very little of the drug is absorbed systemically. 19. The student nurse is studying for a pharmacology exam and notices that many of the adrenergic blocking antagonists drugs studied in class have what suffix? -aine -lol -azole -triptan Ans: B

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TEST BANK - FOCUS ON NURSING
PHARMACOLOGY 9TH EDITION BY
AMY KARCH CHAPTER 1-59 EXAM
2025 LATEST NEWEST UPDATE
WITH ACTUAL QUESTIONS AND
DETAILED VERIFIED ANSWERS
WITH RATIONALES (100%
CORRECT) //BRAND NEW!!
/ALREADY GRADED A+ WITH
GUARANTEED SUCCESS AFTER
DOWNLOAD (ALL YOU NEED TO
PASS YOUR EXAMS

,Test Bank - Focus on Nursing Pharmacology (9th Edition by Karch) 3
Chapter 01 - Introduction to Drugs




What is the nurse's responsibility in pharmacology? (5 steps)

1. administer the drug

2. assess drug effects

3. intervening where needed to make more tolerable

4.providing patient teachings about drugs and the drug regimen

5.monitoring the overall patient care plan to prevent med errors

examples of inorganic compounds used as drugs

aluminum, fluoride, iron, and gold

preclinical trials

Chemicals tested on laboratory animals

phase 1 study

a pilot study of a potential drug using a small number of selected, usually healthy human volunteers

phase 2 study

drugs tested on informed patients with the disease

phase 3 study

Drug used in vast clinical market

phase IV study

continuous evaluation of a drug after it has been released for marketing

in order to be marketed, drugs must be evaluated and approved by the _?

FDA

generic drug

usually named for its chemical structure and is not protected by a brand name or trademark

brand-name drug

Pharmacodynamics

Key word: CHANGE

-the study of the interactions between the chemical components of living organisms (patients) and foreign
chemicals (drugs) being entered into the body

-"how does it change the patients chemistry/body ?"

-method of action

What are the four drug actions?

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,Test Bank - Focus on Nursing Pharmacology (9th Edition by Karch) 4




-replace or act as a substitute for missing chemicals

-increase or stimulate certain cellular activities

- depress or slow cellular activities

- interfere with the functioning of foreign cells

Agonist receptor

binds to a receptor site, stimulates a response (ex- epinephrine stimulates heart rate)

Antagonist receptor

substances or drugs that attach to receptors and prevent them from being activated

competitive antagonist

Drug competes with the agonist for binding to the receptor. If it binds, there is no response.

Non-competitive antagonist

Binds to a site different from the agonist changing the receptor site; not allowing the agonist to bind

Pharmacokinetics

the study of drug movement throughout the body

absorption

distribution

metabolism

excretion

a drug with a registered name or trademark given to a drug by a pharmaceutical company

what occurred in 1938?

Federal Food Drug and cosmetic act

Federal Food, Drug, and Cosmetic Act of 1938

Mandated tests for drug toxicity and provided means for recall of drugs; established procedures for
introducing new drugs; gave FDA the power of enforcement

Controlled Substances Act of 1970

Control over the coding of drugs and the enforcement of these codes to the FDA and the Drug Enforcement
Agency (DEA)

Orphan Drug Act of 1983

Provided incentives for the development of orphan drugs for treatment of rare diseases

Orphan drugs

Drugs that have been discovered, but are not financially viable and therefore have not been "adopted" by
any drug company

Generic name vs Brand/trade name vs chemical name
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, Test Bank - Focus on Nursing Pharmacology (9th Edition by Karch) 5
refer to image

Drug labels are a source of information. What information might a drug label provide?

A. The manufactured date

B. The expiration date

C. When the patent expires

D. The binding properties of the drug

B. The expiration date

over the counter drugs

drugs available to consumers without a prescription

Category A Pregnancy

Studies indicate no risk to the human fetus

Category B pregnancy

No risk to fetus according to animal studies, but there are no adequate human studies

Category C pregnancy

Risk to fetus has been found in animal studies OR there are no good animal studies or human studies

Category D pregnancy

There is evidence of human fetal risk, but the potential benefits from the use of the drug in pregnant women
may be acceptable despite its potential risks.

Category X pregnancy



tolerance

what is the most common route of drug administration in the body?

oral- can be affected by prescience of food in stomach

Distribution routes- way the drugs travel through the body's tissues

Protein Binding

Blood Brain Barrier

Placenta/Breast Milk

in most cases, drugs are best taken on an __, which means an hour before meals, and two after

empty stomach

Excretion

Removal of drugs from the body

Kidneys play the most important role

Two patients are receiving injections of penicillin G. One patient is a male, 35 years old, weighing 165
pounds.
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