ImmunoBiology
• Elements of the immunec c c c
system,
• Types of the immune
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response
• Active and passive immunity
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• Immunoinformatics
• epitope prediction tools
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,Eukaryotic Cells, Bacteria, and Viruses
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, Body Defenses: Overview c c
● Physical barriers: skin & epithelial linings & cilia
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● Chemical: acids, mucous & lysozymes
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● Immune defenses – internal
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● Innate, non-specific, immediate response (min/hrs)
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● Acquired – attack a specific pathogen (antigen)
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● Steps in Immune defense
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● Detect invader/foreign cells
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● Communicate alarm & recruit immune cells c c c c c
● Suppress or destroy invader
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, Discrimination of self from non-self c c c c
“The success of the immune system dep
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ends on its ability to discriminate betw
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een foreign (nonself) and host (self) ce
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lls. Survival requires both the ability to
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mount a destructive immune respons
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e against nonself and the inability to m
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ount a destructive response against s
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elf.”