Test bank for Tietz Fundamentals of Clinical Chemistry an
IIll IIll IIll IIll IIll IIll IIll IIll
IIll Molecular Diagnostics, IIll IIll
8th Edition by Nader Rifai, PhD
IIll IIll IIll IIll IIll IIll
Chapters 1 - 49 IIll IIll IIll IIll
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
IIll IIll IIll IIll IIll IIll IIll IIll
IIll
IIll IIll
Table of contents: IIll IIll
I. Principles Of Laboratory Medicine
IIll IIll IIll IIll
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 3. Clinical Evaluation of Methods
IIll IIll IIll IIll IIll
Chapter 4. Evidence-Based Laboratory Medicine
IIll IIll IIll IIll
Chapter 5. Establishment and Use of Reference Values
IIll IIll IIll IIll IIll IIll IIll
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 7. Quality Management IIll IIll IIll
II. Analytical Techniques And Instrumentation
IIll IIll IIll IIll
Chapter 8. Principles of Basic Techniques and Laboratory Safety
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 9. Optical Techniques IIll IIll IIll
Chapter 10. Electrochemistry and Chemical Sensors
IIll IIll IIll IIll IIll
Chapter 11. Electrophoresis IIll IIll
Chapter 12. Chromatography IIll IIll
Chapter 13. Mass Spectrometry IIll IIll IIll
Chapter 14. Enzyme and Rate Analyses
IIll IIll IIll IIll IIll
Chapter 15. Immunochemical Techniques
IIll IIll IIll
Chapter 16 Automation IIll IIll
Chapter 17. Point-of-Care Instrumentation
IIll IIll IIll
III. AnalytesI I l l
Chapter 18. Amino Acids, Peptides, and Proteins
IIll IIll IIll IIll IIll IIll
Chapter 19. Serum Enzymes IIll IIll IIll
Chapter 20. Tumor Markers and Cancer Genes
IIll IIll IIll IIll IIll IIll
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 22. Carbohydrates IIll IIll
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
IIll IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 24. Electrolytes and Blood Gases
IIll IIll IIll IIll IIll
Chapter 25. Hormones IIll IIll
Chapter 26. Catecholamines and Serotonin
IIll I I l l IIll IIll
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
IIll I I l l IIll IIll IIll IIll
Chapter 28. Hemoglobin, Iron, and Bilirubin
IIll IIll IIll IIll IIll
Chapter 29. Porphyrins and Porphyrias
IIll IIll IIll IIll
Chapter 30. Therapeutic Drugs and Their Management
IIll IIll IIll IIll IIll IIll
Chapter 31. Clinical Toxicology
IIll IIll IIll
Chapter 32. Toxic Metals IIll I I l l IIll
IV. Pathophysiology
I I l l
Chapter 33. Diabetes IIll IIll
,Chapter 34. Cardiovascular Disease
IIll I I l l IIll
Chapter 35. Kidney Disease
IIll IIll IIll
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
IIll I I l l IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 37. Liver Disease
IIll IIll IIll IIll
Chapter 38. Gastrointestinal and Pancreatic Diseases
IIll I I l l IIll IIll IIll
Chapter 39. Disorders of Bone and Mineral Metabolism
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 40. Disorders of the Pituitary Gland
IIll IIll IIll IIll IIll IIll IIll
Chapter 41. Disorders of the Adrenal Cortex
IIll I I l l IIll IIll IIll IIll
Chapter 42. Thyroid Disorders
IIll I I l l IIll
Chapter 43. Reproduction-Related Disorders
IIll I I l l IIll
Chapter 44. Pregnancy and Prenatal Testing
IIll IIll IIll IIll IIll IIll
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
IIll I I l l IIll IIll IIll IIll IIll IIll
Chapter 46. Pharmacogenetics
IIll IIll
V. Molecular Diagnostics
I I l l IIll
Chapter 47. Principles of Molecular Biology
IIll IIll IIll IIll IIll
Chapter 48. Nucleic Acid Techniques and Applications
IIll IIll IIll IIll IIll IIll
Chapter 49. Genomes and Nucleic Acid Alterations
IIll IIll IIll IIll IIll IIll
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
IIll IIll IIll IIll IIll IIll IIll IIll
TestBank
IIll Il
MULTIPLE CHOICE IIll
1. An individual working in a clinical chemistry laboratory is married to a sales
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
representative who works for a company that sells chemistry laboratory supplies. When
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
this individual onlyrecommends the spouse’s company as the vendor. This is considered
IIll IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll
to be a(n):
IIll IIll IIll
a. accounting issue. IIl
b. possible conflict of interest. IIll IIll IIll
c. maintenance of confidentiality issue. IIll IIll IIll
d. problem with resource allocation. IIll IIll IIll
ANS: B IIll
Concern has been raised over the interrelationships between practitioners in the medical
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
profession.
IIll
Similarly, relationships have been scrutinized between clinical laboratorians and
IIll IIll IIll IIll IIll IIll IIll IIll
manufacturers and providers of diagnostic equipment and supplies. These concerns led
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
the National Institutes of Health (NIH) in 1995 to require official institutional review of
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
financial disclosure by researchers and management of situations in which disclosure
IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll
indicates potentialconflicts of interest.
IIll IIll Il IIll IIll
DIF: 1 REF: IIll IIll IIll Page 4-5 IIll OBJ: 6 | 7 IIll IIll Il
2. A patient visits her physician stating that her prescribed painkiller is not working to
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
reduce the pain following her recent surgery. A friend of the patient claims that the
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
same painkiller“worked wonders” to reduce her pain after the same surgery. The
IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
physician states that the difference in the effect of the drug might be caused by
IIll ,
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
which is studied in pharmacogenetics.
IIll IIll IIll IIll IIll
a. epidemiology
b. an inherited disease Il IIll
c. a conflict of interest IIll IIll IIll
d. a genetic variation in drug-metabolizing enzymes
IIll IIll IIll IIll IIll
ANS: D IIll
Pharmacogenetics is the study of the genetic variation of drug metabolism IIll IIll IIll IIll IIll IIll IIll IIll IIll Il
betweenindividuals.
IIll Il
DIF: 1 REF: IIll IIll IIll Page 3 IIll OBJ: 1 IIll
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
the name of a close friend printed on the bar-coded label. The genetic test that is
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
ordered on thefriend’s sample would provide diagnostic information about a disorder
IIll IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll
that has a poor prognosis, and the test is usually performed by John. He asks a fellow
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
employee to analyzethe sample for him and not divulge the results. This ethical issue
IIll IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
concerns:
IIll
a. confidentiality of patient genetic and medical information. IIll IIll IIll IIll IIll IIll
b. a conflict of interest. Il IIll IIll
c. resource allocation. Il
IIll IIll IIll IIll IIll IIll IIll IIll
IIll Molecular Diagnostics, IIll IIll
8th Edition by Nader Rifai, PhD
IIll IIll IIll IIll IIll IIll
Chapters 1 - 49 IIll IIll IIll IIll
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
IIll IIll IIll IIll IIll IIll IIll IIll
IIll
IIll IIll
Table of contents: IIll IIll
I. Principles Of Laboratory Medicine
IIll IIll IIll IIll
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 3. Clinical Evaluation of Methods
IIll IIll IIll IIll IIll
Chapter 4. Evidence-Based Laboratory Medicine
IIll IIll IIll IIll
Chapter 5. Establishment and Use of Reference Values
IIll IIll IIll IIll IIll IIll IIll
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 7. Quality Management IIll IIll IIll
II. Analytical Techniques And Instrumentation
IIll IIll IIll IIll
Chapter 8. Principles of Basic Techniques and Laboratory Safety
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 9. Optical Techniques IIll IIll IIll
Chapter 10. Electrochemistry and Chemical Sensors
IIll IIll IIll IIll IIll
Chapter 11. Electrophoresis IIll IIll
Chapter 12. Chromatography IIll IIll
Chapter 13. Mass Spectrometry IIll IIll IIll
Chapter 14. Enzyme and Rate Analyses
IIll IIll IIll IIll IIll
Chapter 15. Immunochemical Techniques
IIll IIll IIll
Chapter 16 Automation IIll IIll
Chapter 17. Point-of-Care Instrumentation
IIll IIll IIll
III. AnalytesI I l l
Chapter 18. Amino Acids, Peptides, and Proteins
IIll IIll IIll IIll IIll IIll
Chapter 19. Serum Enzymes IIll IIll IIll
Chapter 20. Tumor Markers and Cancer Genes
IIll IIll IIll IIll IIll IIll
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 22. Carbohydrates IIll IIll
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
IIll IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 24. Electrolytes and Blood Gases
IIll IIll IIll IIll IIll
Chapter 25. Hormones IIll IIll
Chapter 26. Catecholamines and Serotonin
IIll I I l l IIll IIll
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
IIll I I l l IIll IIll IIll IIll
Chapter 28. Hemoglobin, Iron, and Bilirubin
IIll IIll IIll IIll IIll
Chapter 29. Porphyrins and Porphyrias
IIll IIll IIll IIll
Chapter 30. Therapeutic Drugs and Their Management
IIll IIll IIll IIll IIll IIll
Chapter 31. Clinical Toxicology
IIll IIll IIll
Chapter 32. Toxic Metals IIll I I l l IIll
IV. Pathophysiology
I I l l
Chapter 33. Diabetes IIll IIll
,Chapter 34. Cardiovascular Disease
IIll I I l l IIll
Chapter 35. Kidney Disease
IIll IIll IIll
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
IIll I I l l IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 37. Liver Disease
IIll IIll IIll IIll
Chapter 38. Gastrointestinal and Pancreatic Diseases
IIll I I l l IIll IIll IIll
Chapter 39. Disorders of Bone and Mineral Metabolism
IIll IIll IIll IIll IIll IIll IIll IIll
Chapter 40. Disorders of the Pituitary Gland
IIll IIll IIll IIll IIll IIll IIll
Chapter 41. Disorders of the Adrenal Cortex
IIll I I l l IIll IIll IIll IIll
Chapter 42. Thyroid Disorders
IIll I I l l IIll
Chapter 43. Reproduction-Related Disorders
IIll I I l l IIll
Chapter 44. Pregnancy and Prenatal Testing
IIll IIll IIll IIll IIll IIll
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
IIll I I l l IIll IIll IIll IIll IIll IIll
Chapter 46. Pharmacogenetics
IIll IIll
V. Molecular Diagnostics
I I l l IIll
Chapter 47. Principles of Molecular Biology
IIll IIll IIll IIll IIll
Chapter 48. Nucleic Acid Techniques and Applications
IIll IIll IIll IIll IIll IIll
Chapter 49. Genomes and Nucleic Acid Alterations
IIll IIll IIll IIll IIll IIll
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
IIll IIll IIll IIll IIll IIll IIll IIll
TestBank
IIll Il
MULTIPLE CHOICE IIll
1. An individual working in a clinical chemistry laboratory is married to a sales
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
representative who works for a company that sells chemistry laboratory supplies. When
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
the laboratory manager requests a list of needed supplies, cost of supplies, and vendors,
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
this individual onlyrecommends the spouse’s company as the vendor. This is considered
IIll IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll
to be a(n):
IIll IIll IIll
a. accounting issue. IIl
b. possible conflict of interest. IIll IIll IIll
c. maintenance of confidentiality issue. IIll IIll IIll
d. problem with resource allocation. IIll IIll IIll
ANS: B IIll
Concern has been raised over the interrelationships between practitioners in the medical
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical
IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
profession.
IIll
Similarly, relationships have been scrutinized between clinical laboratorians and
IIll IIll IIll IIll IIll IIll IIll IIll
manufacturers and providers of diagnostic equipment and supplies. These concerns led
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
the National Institutes of Health (NIH) in 1995 to require official institutional review of
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
financial disclosure by researchers and management of situations in which disclosure
IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll
indicates potentialconflicts of interest.
IIll IIll Il IIll IIll
DIF: 1 REF: IIll IIll IIll Page 4-5 IIll OBJ: 6 | 7 IIll IIll Il
2. A patient visits her physician stating that her prescribed painkiller is not working to
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
reduce the pain following her recent surgery. A friend of the patient claims that the
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
same painkiller“worked wonders” to reduce her pain after the same surgery. The
IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
physician states that the difference in the effect of the drug might be caused by
IIll ,
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
which is studied in pharmacogenetics.
IIll IIll IIll IIll IIll
a. epidemiology
b. an inherited disease Il IIll
c. a conflict of interest IIll IIll IIll
d. a genetic variation in drug-metabolizing enzymes
IIll IIll IIll IIll IIll
ANS: D IIll
Pharmacogenetics is the study of the genetic variation of drug metabolism IIll IIll IIll IIll IIll IIll IIll IIll IIll Il
betweenindividuals.
IIll Il
DIF: 1 REF: IIll IIll IIll Page 3 IIll OBJ: 1 IIll
3. John works in a molecular diagnostics laboratory and receives a blood sample that has
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
the name of a close friend printed on the bar-coded label. The genetic test that is
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
ordered on thefriend’s sample would provide diagnostic information about a disorder
IIll IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll
that has a poor prognosis, and the test is usually performed by John. He asks a fellow
IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
employee to analyzethe sample for him and not divulge the results. This ethical issue
IIll IIll IIll Il IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll IIll
concerns:
IIll
a. confidentiality of patient genetic and medical information. IIll IIll IIll IIll IIll IIll
b. a conflict of interest. Il IIll IIll
c. resource allocation. Il
