NURS 5315 Module 3, #2Disorders of the Immune System Study Guide.

Disorders of the Immune System 2. Differentiate between the etiology, clinical manifestations and pathophysiology of select disorders of the immune system. Hypersensitivity: an altered immunologic response to an antigen that results in disease or damage to the host. Hypersensitivity reaction: can be classified in 2 ways - by the source of the antigen that the immune system is attacking (allergy, autoimmunity, alloimmunity) - by the mechanism that causes the disease (types I, II, III, IV) a. Evaluate the etiology, clinical manifestations and pathophysiology of Type I, Type II, Type III, and Type IV hypersensitivities and describe the implications clinical practice. -the four mechanisms are interrelated, and in most hypersensitivity reactions, several mechanism can be at work simultaneously or sequentially Hypersensitivity Etiology Clinical M