Fundamental Virology
Introduction and History
Diane Griffin
September 5, 2018
Background micrograph: Human Adenovirus 5 by Egbert Hoiczyk
, Fundamental Virology
Course Themes
• Virus interactions with the host cell
– Entry
– Genome replication and expression
– Assembly and escape
– Intracellular antiviral mechanisms
• Virus interactions with the host organism
– Pathogenesis and disease mechanisms
– Immune responses to viral infections
• Virus interactions with host populations
– Mechanisms of persistence
– Emerging, epidemic and pandemic diseases
, Fundamental Virology
• TEXT: Principles of Virology, Flint et al, 4th
Edition
•Course directors:
•Diane Griffin –
•Andrew Pekosz –
• Students need a basic knowledge of cell
biology and molecular biology
• Slides, handouts and Panopto files on
CoursePlus
, Teaching Assistants and
Tests
Introduction and History
Diane Griffin
September 5, 2018
Background micrograph: Human Adenovirus 5 by Egbert Hoiczyk
, Fundamental Virology
Course Themes
• Virus interactions with the host cell
– Entry
– Genome replication and expression
– Assembly and escape
– Intracellular antiviral mechanisms
• Virus interactions with the host organism
– Pathogenesis and disease mechanisms
– Immune responses to viral infections
• Virus interactions with host populations
– Mechanisms of persistence
– Emerging, epidemic and pandemic diseases
, Fundamental Virology
• TEXT: Principles of Virology, Flint et al, 4th
Edition
•Course directors:
•Diane Griffin –
•Andrew Pekosz –
• Students need a basic knowledge of cell
biology and molecular biology
• Slides, handouts and Panopto files on
CoursePlus
, Teaching Assistants and
Tests
