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WGU D115 ADVANCED
PATHOPHYSIOLOGY FOR THE
ADVANCED PRACTICE NURSE
MASTER SET EXAM 2026 |
QUESTIONS AND VERIFIED ANSWERS
| ALREADY A GRADED | NEW AND
REVISED!!
What is a red flag for low healthcare literacy? - ANSWER- Low literacy
often leads to perceived noncompliance to medical instructions,
including medication instructions. Ensuring the patient fully understands
all instructions is critical for understanding.
Amniocentesis is recommended for pregnant women with certain health
histories.
Which health history would result in an amniocentesis recommendation?
- ANSWER- Those who have a family history of genetic disorders
Studies have identified several genes that play a role in the prevention of
obesity.
What do these genes influence? - ANSWER- Regulation of appetite-
Research has shown that genetic mutations may cause alterations in the
regulation of appetite.
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,2|Page
Which concept is data reporting that sickle cell disease affects
approximately 1 in 600 black Americans an example of? - ANSWER-
Prevalence tells us how often disease is seen in a population, which
includes all people with the disease at a given time, at any stage in the
disease progression.
What describes a chromosomal defect caused by Prader-Willi
syndrome? - ANSWER- Prader-Willi syndrome is caused by a disorder
of a portion of chromosome 15. Normally, a portion of this chromosome
is inherited from both parents. With Prader-Willi syndrome, the
chromosome inherited from the father is problematic.
Which action is a purpose of the inflammatory process? - ANSWER-
Prevent infection of the injured tissue
The inflammatory response is a defense mechanism designed to remove
damaged tissue so the body can heal.
Which leukocytes are elevated in response to acute inflammatory
reactions when considering white blood cell differentials?
Monocytes
Neutrophils
Basophils
Eosinophils - ANSWER- Neutrophils are one of the first responders to
acute inflammation, and an increase in neutrophils demonstrates an
acute inflammatory response.
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Which type of immunity is produced by an individual after either natural
exposure to the antigen or after immunization against the antigen? -
ANSWER- Active-acquired immunity or naturally acquired active
immunity occurs when an individual is exposed to a live pathogen and
develops the disease or becomes immune as a result of a vaccine.
Which characteristics do atopic individuals have that make them
genetically predisposed to develop allergies? - ANSWER- The greater
quantities of IgE in atopic individuals make them genetically
predisposed to develop allergies. IgE mediates the immune response to
allergens; therefore, the more IgE one has, the stronger the response can
be to an allergen. Think of it as having more soldiers in the army to fight
the war.
A healthcare professional is conducting community education on
vaccinations.
Which statement about vaccines should the professional include in the
presentation? - ANSWER- Vaccines require booster injections to
maintain life-long protection.
Most vaccines require a booster to increase immunity. The initial effects
of a vaccine may diminish over time, and boosters improve protection
against disease.
Which term describes an agent's ability to produce disease? - ANSWER-
Pathogenicity refers to an organism's ability to create or produce disease.
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What are signs and symptoms of Cri du Chrat Syndrome? - ANSWER-
DNA deletion of chromosome 5. low birth weight, mental retardation,
microencephaly, and cat like cry
What are the 3 layers of human defense? - ANSWER- Physical,
Mechanical, biochemical barriers
What happens in the physical layer of human defense. - ANSWER-
protect against damage and infection are composed of tightly associated
epithelial cells including those of the skin and of the membranous sheets
lining the gastrointestinal, genitourinary, and respiratory tracts.
What is the second line of defense and the process? - ANSWER-
Inflammatory response- rapid and nonspecific, protective response to
cellular injury from any cause. It can occur only in vascularized tissue.
How do acute and chronic inflammation differ? - ANSWER- Acute-
Short duration, 8-10 days from onset to healing.
Chronic inflammation- can be a continuation of acute inflammation that
last 2 weeks or longer. It can also occur as a distinct process without
much preceding acute inflammation
What three systemic changes associated with acute inflammatory
response - ANSWER- Fever, leukocytosis, plasma protein synthesis
4|Page
WGU D115 ADVANCED
PATHOPHYSIOLOGY FOR THE
ADVANCED PRACTICE NURSE
MASTER SET EXAM 2026 |
QUESTIONS AND VERIFIED ANSWERS
| ALREADY A GRADED | NEW AND
REVISED!!
What is a red flag for low healthcare literacy? - ANSWER- Low literacy
often leads to perceived noncompliance to medical instructions,
including medication instructions. Ensuring the patient fully understands
all instructions is critical for understanding.
Amniocentesis is recommended for pregnant women with certain health
histories.
Which health history would result in an amniocentesis recommendation?
- ANSWER- Those who have a family history of genetic disorders
Studies have identified several genes that play a role in the prevention of
obesity.
What do these genes influence? - ANSWER- Regulation of appetite-
Research has shown that genetic mutations may cause alterations in the
regulation of appetite.
1|Page
,2|Page
Which concept is data reporting that sickle cell disease affects
approximately 1 in 600 black Americans an example of? - ANSWER-
Prevalence tells us how often disease is seen in a population, which
includes all people with the disease at a given time, at any stage in the
disease progression.
What describes a chromosomal defect caused by Prader-Willi
syndrome? - ANSWER- Prader-Willi syndrome is caused by a disorder
of a portion of chromosome 15. Normally, a portion of this chromosome
is inherited from both parents. With Prader-Willi syndrome, the
chromosome inherited from the father is problematic.
Which action is a purpose of the inflammatory process? - ANSWER-
Prevent infection of the injured tissue
The inflammatory response is a defense mechanism designed to remove
damaged tissue so the body can heal.
Which leukocytes are elevated in response to acute inflammatory
reactions when considering white blood cell differentials?
Monocytes
Neutrophils
Basophils
Eosinophils - ANSWER- Neutrophils are one of the first responders to
acute inflammation, and an increase in neutrophils demonstrates an
acute inflammatory response.
2|Page
,3|Page
Which type of immunity is produced by an individual after either natural
exposure to the antigen or after immunization against the antigen? -
ANSWER- Active-acquired immunity or naturally acquired active
immunity occurs when an individual is exposed to a live pathogen and
develops the disease or becomes immune as a result of a vaccine.
Which characteristics do atopic individuals have that make them
genetically predisposed to develop allergies? - ANSWER- The greater
quantities of IgE in atopic individuals make them genetically
predisposed to develop allergies. IgE mediates the immune response to
allergens; therefore, the more IgE one has, the stronger the response can
be to an allergen. Think of it as having more soldiers in the army to fight
the war.
A healthcare professional is conducting community education on
vaccinations.
Which statement about vaccines should the professional include in the
presentation? - ANSWER- Vaccines require booster injections to
maintain life-long protection.
Most vaccines require a booster to increase immunity. The initial effects
of a vaccine may diminish over time, and boosters improve protection
against disease.
Which term describes an agent's ability to produce disease? - ANSWER-
Pathogenicity refers to an organism's ability to create or produce disease.
3|Page
, 4|Page
What are signs and symptoms of Cri du Chrat Syndrome? - ANSWER-
DNA deletion of chromosome 5. low birth weight, mental retardation,
microencephaly, and cat like cry
What are the 3 layers of human defense? - ANSWER- Physical,
Mechanical, biochemical barriers
What happens in the physical layer of human defense. - ANSWER-
protect against damage and infection are composed of tightly associated
epithelial cells including those of the skin and of the membranous sheets
lining the gastrointestinal, genitourinary, and respiratory tracts.
What is the second line of defense and the process? - ANSWER-
Inflammatory response- rapid and nonspecific, protective response to
cellular injury from any cause. It can occur only in vascularized tissue.
How do acute and chronic inflammation differ? - ANSWER- Acute-
Short duration, 8-10 days from onset to healing.
Chronic inflammation- can be a continuation of acute inflammation that
last 2 weeks or longer. It can also occur as a distinct process without
much preceding acute inflammation
What three systemic changes associated with acute inflammatory
response - ANSWER- Fever, leukocytosis, plasma protein synthesis
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