Berne and Levy Physiology 7th Edition KoeppenTest Bank
h1 h1 h1 h1 h1 h1 h1
, Koeppen: Berne and Levy Physiology, 7th Edition h1 h1 h1 h1 h1 h1
Chapter 01: Principles of Cell h1 h1 h1 h1
FunctionTest Bank
h1 h1
Multiple Choice h1
1. The subcellular structure that degrades proteins is called the:
h1 h1 h1 h1 h1 h1 h1 h1
A. Tight junction h1
B. Mitochondria
C. Lysosome
D. Plasma membrane h1
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
following data are obtained:
h1 h1 h1 h1
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
the cell from making adenosine triphosphate (ATP), the uptake of amino acid into the
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
cell is markedly reduced. According to this information, which of the
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
followingmechanisms is probably responsible for the transport of the amino acid into
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
the cell?
h1 h1
A. Passive diffusion through the lipid bilayer h1 h1 h1 h1 h1
B. Uniporter
C. Transport ATPase h1
D. Na+ symporter h1
E. Na+antiporter
ANS: D
h1 h 1
3. Amembrane permeable byonly Na+ separatestwo compartments
h1 h1 h1 h1 h1
containing Na2SO4,shown as follows:
h1 h1 h1 h1
,Electrodes are placed in both compartments, and a voltage is applied (that of
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
compartment A is held at 0 mV). What voltage applied to compartment B would
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
resultin no net movement of Na+ across the membrane separating the compartments?
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
–60 mV
A. h1
–30 mV
B. h1
C.
0 mV h1
D. +30 mV h1
E. +60mV
ANS: E h 1 h 1
4. The restingmembrane potentNial oRf a Ic ellGis –B
h1 85.mCV. The intracellular and h1 h1 h1 h1 h 1 h 1 h1 h1
extracellular concentrations ofUseveral
h1
SN ions are indicated in the following table,
h1 h1 h1
1
h 1
h
h1 h1 h1 h1 h1 h1 h1
as is the calculated
h1 h1 h1 h1
Nernst equilibrium potential (Ei) for each of these ions:
h1 h1 h1 h1 h1 h1 h1 h1
Ion Concentration Concentration Ei
Inside Cell h1 Outside Cell h1
+
Na 12 mEq/L h1 145 mEq/L h1 66 mV h1
K+ 150 mEq/L h1 4 mEq/L h1 –96 mV h1
Cl– 30 mEq/L h1 105 mEq/L h1 –33 mV h1
Ca++ 0.0001 mmol/dL h1 1 mmol/dLh1 122 mV h1
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
membrane is the greatest for which ion?
h1 h1 h1 h1 h1 h1 h1
A. Na+
B. K+
C. Cl–
D. Ca++
AN h 1
S:
B
5. A cell contains the following membrane transporters:
h1 h1 h1 h1 h1 h1
Na+channelK+channel
1
h h1
Na+,K+-ATPase
h1
The resting membrane voltage of the cell is –80 mV, and the intracellular and
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
, extracellular ion concentrations are as follows:
h1 h1 h1 h1 h1
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L h1 145 mEq/L h1
K+ 120 mEq/L h1 4 mEq/L h1
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug on
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
the following parameters?
h1 h1 h1
Intracellular [Na+] h1 Intracellular [K+] h1 Cell Volumeh1 Membrane Voltage h1
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
h1
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
a glycosylphosphatidylinositol (GPI) anchor?
h1 h1 h1 h1
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting
h1 h1 h1 h1 h1 h1 h1 h1
h 1
h1 h1 h1 h1 h1
membrane potential is –60 mV (cell interior negative). The intracellular and
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
extracellular concentrations for these ions, as well as the calculated Nernst
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
potentials, are listed as follows:
h1 h1 h1 h1 h1
h1 h1 h1 h1 h1 h1 h1
, Koeppen: Berne and Levy Physiology, 7th Edition h1 h1 h1 h1 h1 h1
Chapter 01: Principles of Cell h1 h1 h1 h1
FunctionTest Bank
h1 h1
Multiple Choice h1
1. The subcellular structure that degrades proteins is called the:
h1 h1 h1 h1 h1 h1 h1 h1
A. Tight junction h1
B. Mitochondria
C. Lysosome
D. Plasma membrane h1
E. Ribosome
ANS: C
2. An experiment is done to measure the uptake of an amino acid into a cell. The
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
following data are obtained:
h1 h1 h1 h1
N
If Na+ is removed from the extracellular bathing solution, or if a drug is added that prevents
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
the cell from making adenosine triphosphate (ATP), the uptake of amino acid into the
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
cell is markedly reduced. According to this information, which of the
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
followingmechanisms is probably responsible for the transport of the amino acid into
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
the cell?
h1 h1
A. Passive diffusion through the lipid bilayer h1 h1 h1 h1 h1
B. Uniporter
C. Transport ATPase h1
D. Na+ symporter h1
E. Na+antiporter
ANS: D
h1 h 1
3. Amembrane permeable byonly Na+ separatestwo compartments
h1 h1 h1 h1 h1
containing Na2SO4,shown as follows:
h1 h1 h1 h1
,Electrodes are placed in both compartments, and a voltage is applied (that of
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
compartment A is held at 0 mV). What voltage applied to compartment B would
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
resultin no net movement of Na+ across the membrane separating the compartments?
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
–60 mV
A. h1
–30 mV
B. h1
C.
0 mV h1
D. +30 mV h1
E. +60mV
ANS: E h 1 h 1
4. The restingmembrane potentNial oRf a Ic ellGis –B
h1 85.mCV. The intracellular and h1 h1 h1 h1 h 1 h 1 h1 h1
extracellular concentrations ofUseveral
h1
SN ions are indicated in the following table,
h1 h1 h1
1
h 1
h
h1 h1 h1 h1 h1 h1 h1
as is the calculated
h1 h1 h1 h1
Nernst equilibrium potential (Ei) for each of these ions:
h1 h1 h1 h1 h1 h1 h1 h1
Ion Concentration Concentration Ei
Inside Cell h1 Outside Cell h1
+
Na 12 mEq/L h1 145 mEq/L h1 66 mV h1
K+ 150 mEq/L h1 4 mEq/L h1 –96 mV h1
Cl– 30 mEq/L h1 105 mEq/L h1 –33 mV h1
Ca++ 0.0001 mmol/dL h1 1 mmol/dLh1 122 mV h1
The membrane has channels for Na+, K+, Cl–, and Ca++. The conductance of the
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
membrane is the greatest for which ion?
h1 h1 h1 h1 h1 h1 h1
A. Na+
B. K+
C. Cl–
D. Ca++
AN h 1
S:
B
5. A cell contains the following membrane transporters:
h1 h1 h1 h1 h1 h1
Na+channelK+channel
1
h h1
Na+,K+-ATPase
h1
The resting membrane voltage of the cell is –80 mV, and the intracellular and
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
, extracellular ion concentrations are as follows:
h1 h1 h1 h1 h1
Ion Intracellular Extracellular
Concentration Concentration
Na+ 10 mEq/L h1 145 mEq/L h1
K+ 120 mEq/L h1 4 mEq/L h1
The cell is treated with a drug to inhibit the Na+,K+-ATPase. What would be the effect ofthis drug on
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
the following parameters?
h1 h1 h1
Intracellular [Na+] h1 Intracellular [K+] h1 Cell Volumeh1 Membrane Voltage h1
A. Decrease Decrease Decrease Depolarize
B. Increase Decrease Increase Depolarize
C. Increase Increase Increase No change
h1
D. Decrease Increase Decrease Hyperpolarize
E. Increase Increase Decrease Hyperpolarize
ANS: B
6. Which of the labeled proteins (shaded) is attached to the membrane by
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
a glycosylphosphatidylinositol (GPI) anchor?
h1 h1 h1 h1
ANS: E
7. A cell has channels for Na+, K+, and Cl– in its plasma membrane. The resting
h1 h1 h1 h1 h1 h1 h1 h1
h 1
h1 h1 h1 h1 h1
membrane potential is –60 mV (cell interior negative). The intracellular and
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
extracellular concentrations for these ions, as well as the calculated Nernst
h1 h1 h1 h1 h1 h1 h1 h1 h1 h1 h1
potentials, are listed as follows:
h1 h1 h1 h1 h1
