Harrison's Principles of Internal Medicine (Vol.1
& Vol.2)
21st Edition Newer Edition
Author(s)Joseph Loscalzo; Anthony S. Fauci;
Dennis L. Kasper; Stephen Hauser; Dan Longo; J.
Larry Jameson
TEST BANK
1) Reference
Ch. 1 — The Practice of Medicine
Question Stem
A 68-year-old man with multiple chronic diseases asks whether
his congestive symptoms are best managed by aggressive
,single-disease protocols or by prioritizing his functional goals.
Which approach most aligns with patient-centered practice?
Options
A. Apply disease-specific guideline algorithms for each
condition independently.
B. Prioritize interventions that maximize the patient’s overall
function and quality of life.
C. Defer all decisions to the specialist with the most relevant
organ expertise.
D. Use the most intensive therapy available to prolong survival
regardless of side effects.
Correct Answer
B
Rationales
Correct: Prioritizing overall function and quality of life embodies
patient-centered care and reconciles multiple conditions with
patient goals.
A: Applying siloed guideline algorithms can produce conflicting
treatments and increased harm in multimorbidity.
C: Solely deferring to one specialist risks fragmented care and
neglects the patient’s values.
D: Intensifying therapy without regard to trade-offs may reduce
quality of life and cause harm.
Teaching Point
Patient-centered care aligns treatment with patient goals across
comorbidities.
,Citation
Loscalzo et al. (2022). Harrison’s Principles of Internal Medicine
(21st Ed.). Ch. 1.
2) Reference
Ch. 2 — Promoting Good Health
Question Stem
A primary care clinic is designing a smoking-cessation program
for a socioeconomically disadvantaged neighborhood. Which
program element will most likely increase long-term quit rates?
Options
A. One-time distribution of printed brochures about quitting.
B. Short-term nicotine patch supply with no follow-up.
C. Repeated counseling sessions combined with
pharmacotherapy and community support.
D. Posting mass-media ads encouraging quitting without local
referral resources.
Correct Answer
C
Rationales
Correct: Combining behavioral counseling, pharmacotherapy,
and community support addresses addiction biologically and
socially, improving sustained quit rates.
A: Brochures alone rarely change behavior in high-risk
populations.
, B: Short-term patch use without follow-up has limited long-
term effectiveness.
D: Mass-media campaigns raise awareness but are insufficient
without local supports.
Teaching Point
Multimodal interventions (counseling + meds + support)
improve cessation outcomes.
Citation
Loscalzo et al. (2022). Harrison’s Principles of Internal Medicine
(21st Ed.). Ch. 2.
3) Reference
Ch. 3 — Vaccine Opposition and Hesitancy
Question Stem
A pediatrician encounters a family refusing MMR vaccination
due to safety fears. Which response is the most effective
application of motivational interviewing to reduce hesitancy?
Options
A. Provide a lecture listing statistical safety data for the vaccine.
B. Insist that refusal will lead to discharge from the practice.
C. Explore the family’s specific concerns, affirm their values, and
invite questions.
D. Dismiss their worries as misinformation and refuse further
discussion.
& Vol.2)
21st Edition Newer Edition
Author(s)Joseph Loscalzo; Anthony S. Fauci;
Dennis L. Kasper; Stephen Hauser; Dan Longo; J.
Larry Jameson
TEST BANK
1) Reference
Ch. 1 — The Practice of Medicine
Question Stem
A 68-year-old man with multiple chronic diseases asks whether
his congestive symptoms are best managed by aggressive
,single-disease protocols or by prioritizing his functional goals.
Which approach most aligns with patient-centered practice?
Options
A. Apply disease-specific guideline algorithms for each
condition independently.
B. Prioritize interventions that maximize the patient’s overall
function and quality of life.
C. Defer all decisions to the specialist with the most relevant
organ expertise.
D. Use the most intensive therapy available to prolong survival
regardless of side effects.
Correct Answer
B
Rationales
Correct: Prioritizing overall function and quality of life embodies
patient-centered care and reconciles multiple conditions with
patient goals.
A: Applying siloed guideline algorithms can produce conflicting
treatments and increased harm in multimorbidity.
C: Solely deferring to one specialist risks fragmented care and
neglects the patient’s values.
D: Intensifying therapy without regard to trade-offs may reduce
quality of life and cause harm.
Teaching Point
Patient-centered care aligns treatment with patient goals across
comorbidities.
,Citation
Loscalzo et al. (2022). Harrison’s Principles of Internal Medicine
(21st Ed.). Ch. 1.
2) Reference
Ch. 2 — Promoting Good Health
Question Stem
A primary care clinic is designing a smoking-cessation program
for a socioeconomically disadvantaged neighborhood. Which
program element will most likely increase long-term quit rates?
Options
A. One-time distribution of printed brochures about quitting.
B. Short-term nicotine patch supply with no follow-up.
C. Repeated counseling sessions combined with
pharmacotherapy and community support.
D. Posting mass-media ads encouraging quitting without local
referral resources.
Correct Answer
C
Rationales
Correct: Combining behavioral counseling, pharmacotherapy,
and community support addresses addiction biologically and
socially, improving sustained quit rates.
A: Brochures alone rarely change behavior in high-risk
populations.
, B: Short-term patch use without follow-up has limited long-
term effectiveness.
D: Mass-media campaigns raise awareness but are insufficient
without local supports.
Teaching Point
Multimodal interventions (counseling + meds + support)
improve cessation outcomes.
Citation
Loscalzo et al. (2022). Harrison’s Principles of Internal Medicine
(21st Ed.). Ch. 2.
3) Reference
Ch. 3 — Vaccine Opposition and Hesitancy
Question Stem
A pediatrician encounters a family refusing MMR vaccination
due to safety fears. Which response is the most effective
application of motivational interviewing to reduce hesitancy?
Options
A. Provide a lecture listing statistical safety data for the vaccine.
B. Insist that refusal will lead to discharge from the practice.
C. Explore the family’s specific concerns, affirm their values, and
invite questions.
D. Dismiss their worries as misinformation and refuse further
discussion.
