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RN Pharmacology A – 2025/2026 | 30 Exam Questions with Answers | NCLEX Prep – Dosage, Toxicity, IV Safety

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This document features 30 carefully structured exam questions with verified A+ answers for RN Pharmacology A, designed for the 2025/2026 academic year. It is a high-impact resource for mastering nursing pharmacology, covering a wide range of essential topics such as medication administration, drug interactions, therapeutic monitoring, dosage calculations, and toxicity management. Key clinical scenarios include: Holding digoxin based on heart rate and potassium levels Safe infusion practices for vancomycin and furosemide Identifying and managing adverse reactions (e.g., tinnitus, nephrotoxicity) Reversal agents for narcotic overdose (e.g., naloxone) Insulin timing and sliding scale interpretation Dietary considerations with anticoagulants like warfarin Calculating weight-based dosages and IV rates This resource is ideal for: Nursing students enrolled in ADN, BSN, or direct-entry MSN programs NCLEX-RN candidates preparing for the pharmacology section Students enrolled in RN Pharmacology A courses Learners in U.S.-based nursing schools and universities seeking exam-focused content Comprehensive and clinically relevant, this document is structured to reinforce safe pharmacological practice and support students in achieving success on exams and licensure tests. Keywords: RN pharmacology, nursing exam questions, NCLEX preparation, IV medication safety, dosage calculations, drug interactions, pharmacology review, nephrotoxic drugs, antidotes in nursing, digoxin monitoring, insulin administration, warfarin diet interactions, vancomycin infusion, morphine overdose reversal, prednisone tapering, aspirin pharmacology, central line nursing care, emergency medications, side effects management, clinical nursing scenarios

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RN Pharmacology A 2025/2026 Exam
Questions and Verified Answers |
Already Graded A+



Which of the following medications is known to cause orange-colored

urine? - 🧠 ANSWER ✔✔phenazopyridine (Pyridium)


You are ordered to give digoxin. Your patient's vital signs are as follows:

Blood Pressure 130/75, Temp 97.9 oral, HR 52, O2 Sat 100% room air.

What should you do next? - 🧠 ANSWER ✔✔Hold digoxin and call the

provider

Normal Saline (NS) is the solution of choice over D5W when preparing to

administer a blood transfusion because: - 🧠 ANSWER ✔✔Normal Saline is

an isotonic solution and prevents cell hemolysis

Patient is to receive 5mg/kg of medication. Patient weighs 80kg. How much

would you administer? - 🧠 ANSWER ✔✔400mg

, Your patient taking digoxin (Lanoxin) has an AM Potassium level of 3.0.

This level may: - 🧠 ANSWER ✔✔Increase risk of digoxin toxicity


The patient is diagnosed with multiple myeloma. The physician has ordered

cyclophosphamide (Cytoxan). Which instruction should be given to the

patient? - 🧠 ANSWER ✔✔Increase daily water intake


Which of the following medications will crystalize when mixed with D5NS? -

🧠 ANSWER ✔✔phenytoin (Dilantin)


Which of the following medications should be questioned by the nurse, if

ordered by the provider to treat a patient's complaint of nausea and

vomiting? - 🧠 ANSWER ✔✔famotidine (Pepcid)


Your patient has an epidural infusing hydromorphone with bupivacaine at

6ml/hr continuously. The patient's blood pressure at the beginning of your

shift was 92/58 with a heart rate of 68. You noticed the patient's blood

pressures have been around 130/70. What should you do FIRST? - 🧠

ANSWER ✔✔Check infusion rate to confirm 6ml/hr, then notify anesthesia

provider

The dosage of which drug must be tapered off slowly to prevent acute

adrenal insufficiency? - 🧠 ANSWER ✔✔prednisone (Deltasone)

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