WGU D027 Advanced Pathopharmacological
Foundations Latest Update 2024-2025, 100%
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What organ does cystic fibrosis affect? - ANSWER Affects the pancreas causing secretions into the lungs
What is Klinefelter syndrome? - ANSWER An extra X chromosome for males so example XXY causing
female-like qualities
What is Turner Syndrome? - ANSWER females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation disorders, visual spatial and attentional
problems
What is beta thalassemia? - ANSWER a condition in which the synthesis of the beta-globin chains is
decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - ANSWER Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly toxic to
lymphoid tissues Selective estrogen receptor modulators (SERM) - for hormone receptor positive and
advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk) - ANSWER Glucocorticoids
What is the normal ejection fraction? - ANSWER 55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWER Preserved
, What are symptoms of left sided heart failure? - ANSWER Think PULMONARY. JVD, FVO, rails, S3
murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - ANSWER Think peripheral vascular. Lower extremity
edema, abdominal distension.
What is the gold standard lab test for heart failure? - ANSWER BNP. Heart failure is a result greater than
100
What heart disease is worse with exertion? - ANSWER Ischemic heart disease because the demand
requirements are higher.
What should you assess before giving Digoxin? - ANSWER Apical pulse
How should Warfarin be started? - ANSWER Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to hyperinflation
- ANSWER Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - ANSWER Bronchitis
What is a chronic inflammatory obstruction of bronchi? - ANSWER Asthma, Triggers cause mucus to clog
bronchial tubes.
What causes an overbite and buffalo hump? - ANSWER Endocrine disorder called acromegaly
(overproduction of growth hormone)
What causes Addison's disease? - ANSWER Decreased glucocorticoid (due to autoimmune destruction of
adrenal cortex)
What causes Cushing's syndrome? - ANSWER excess cortisol
Foundations Latest Update 2024-2025, 100%
guaranteed pass, all bundled to boost and
ease your study
What organ does cystic fibrosis affect? - ANSWER Affects the pancreas causing secretions into the lungs
What is Klinefelter syndrome? - ANSWER An extra X chromosome for males so example XXY causing
female-like qualities
What is Turner Syndrome? - ANSWER females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation disorders, visual spatial and attentional
problems
What is beta thalassemia? - ANSWER a condition in which the synthesis of the beta-globin chains is
decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - ANSWER Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly toxic to
lymphoid tissues Selective estrogen receptor modulators (SERM) - for hormone receptor positive and
advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk) - ANSWER Glucocorticoids
What is the normal ejection fraction? - ANSWER 55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWER Preserved
, What are symptoms of left sided heart failure? - ANSWER Think PULMONARY. JVD, FVO, rails, S3
murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - ANSWER Think peripheral vascular. Lower extremity
edema, abdominal distension.
What is the gold standard lab test for heart failure? - ANSWER BNP. Heart failure is a result greater than
100
What heart disease is worse with exertion? - ANSWER Ischemic heart disease because the demand
requirements are higher.
What should you assess before giving Digoxin? - ANSWER Apical pulse
How should Warfarin be started? - ANSWER Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to hyperinflation
- ANSWER Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - ANSWER Bronchitis
What is a chronic inflammatory obstruction of bronchi? - ANSWER Asthma, Triggers cause mucus to clog
bronchial tubes.
What causes an overbite and buffalo hump? - ANSWER Endocrine disorder called acromegaly
(overproduction of growth hormone)
What causes Addison's disease? - ANSWER Decreased glucocorticoid (due to autoimmune destruction of
adrenal cortex)
What causes Cushing's syndrome? - ANSWER excess cortisol
