VUSN Pharm 5106 Pharmacology and Diabetes Exam Practice Questions and Answers (100% Pass)

VUSN Pharm 5106 Pharmacology and Diabetes Exam Practice Questions and Answers (100% Pass) What is Type I diabetes? - Answer️️ -juvenile onset characterized by destruction of beta cells of the pancreas which are responsible for insulin synthesis significant hyperglycemia at presentation What are some clinical signs that a child has Type I diabetes? - Answer️️ - gets sick frequently has to urinate frequently What is insulin? - Answer️️ -hormone necessary for normal carb, protein and fat metabolism increases uptake of glucose by tissues What organs does insulin have the greatest effect on? - Answer️️ -liver muscle adipose tissue What are the effects of insulin deficiency? - Answer️️ -↑ glycogenolysis (generation of free glucose from breakdown of glycogen) ↑ gluconeogensis ↓ glucose utilization ©SOPHIABENNETT@ Sunday, August 25, 2024 2:42 PM Vanderbilt University School of Nursing 2 ↓ cellular uptake of glucose What is insulin therapy defined by? - Answer️️ -onset, peak and duration rapid: 15-30min, 0.5-2.5hr, 3-6.5hr short: 30-60min, 1-5hr, 6-10hr intermediate: 60-180min, 6-14hr, 15hr long: 70min, ?, 24hr What is the #1 complication associated with insulin treatment? - Answer️️ -hypoglycemia What are the different types of rapid insulin? - Answer️️ -Lispro (Humalog/Novalog) What are the different types of short insulin? - Answer️️ -regular (natural) What are the different types of intermediate insulin? - Answer️️ -NPH (Humulin N, Novolin N) What are the different types of long insulin? - Answer️️ -Glargine (Lantus) ©SOPHIABENNETT@ Sunday, August 25, 2024 2:42 PM Vanderbilt University School of Nursing 3 Insulin Detemir (Levemir) What are commercially mixed insulins? - Answer️️ -Humulin 70/30 Humulin 50/50 Novulin 70/30 Novolog 70/30 Humalog 75/25 What insulins can be mixed? - Answer️️ -NPH with humalog/regular How should you mix NPH with humalog/regular insulin? - Answer️️ - "clear to cloudy" humalog/regular = clear NPH = cloudy Why do you want to mix "clear to cloudy?" - Answer️️ -if humalog/regular get into NPH, patient is still monitored over longer period of time if NPH gets into humalog/regular, you won't know to monitor delayed onset, peak and duration What insulins cannot be mixed? - Answer️️ -humalog cannot be mixed with regular ©SOPHIABENNETT@ Sunday, August 25, 2024 2:42 PM Vanderbilt University School of Nursing 4 long (Lantus/Levemir) cannot be mixed with anything How should you administer insulin? - Answer️️ -give subQ using insulin syringes ONLY rotate and check injection sites (prevents lipodistrophy) vial can remain in room temp for 1 month after opened read dr. orders review chart to see when last dose was given is client NPO?? What is lipodistrophy? - Answer️️ -a thickening und