Neurotransmitters
Dopamine (Nor)Adrenaline Serotonine GABA (rem) Glutamaat (gas) Acetylcholine
Glutamaat
Choline en acetyl
Precursor Tyrosine Tyrosine Tryptofaan (andere aminozuren zoals
Glutamine coenzym A
glucose en pyruvaal)
Tyrosine hydroxylase Dopamine bèta hydroxylase Hydroxylase (5-
GAD (glutamic acid
Enzym (levodopa) (noradrenaline) hydroxytryptofaan)
decarboxylase)
Dopadecarbocylase PNMT (adrenaline) Decarboxylase (5HT)
Adrenerg: hersenstam naar
hypothalamus
Dopaminerge: substantia Noradrenerg: Locus 5HTerge: raphe Cortico-striatale-
Banen
nigra en tegmentum Coeruleus naar cortex, nucleus thalamische-corticale loop
thalamus, hippocampus,
cerebellum, etc.
Vesikel Acetylcholine
VMAT 2 VMAT 2 VMAT 2 VIAAT VGLUTS
transporters transporters
Ionotrope: AMPA, Ionotrope: nicotine
Ionotrope GABA a+c Kainaat, NMDA receptor
Receptoren g-proteïne: D1-5 GPCR’s: α + β GPCR’s: 5HT
Metabotrope: GABA b Metabotrope: Metabotrope: Muscarine
glutamaatreceptor I-III (M1-M5)
Heropname Noradrenaline Transporter Serotonine Transporter GAT
Dopaminetransporter Aminozuur Transporters X
transporters (NET) (SERT) Astrocyten en gliacellen
Acetylcholinesterase
Enzym
MAO + COMT MAO + COMT MAO GABA-T Glutamine synthetase Gliaal
metabolieten
butytylcholinesterase
Dopamine (Nor)Adrenaline Serotonine GABA (rem) Glutamaat (gas) Acetylcholine
Glutamaat
Choline en acetyl
Precursor Tyrosine Tyrosine Tryptofaan (andere aminozuren zoals
Glutamine coenzym A
glucose en pyruvaal)
Tyrosine hydroxylase Dopamine bèta hydroxylase Hydroxylase (5-
GAD (glutamic acid
Enzym (levodopa) (noradrenaline) hydroxytryptofaan)
decarboxylase)
Dopadecarbocylase PNMT (adrenaline) Decarboxylase (5HT)
Adrenerg: hersenstam naar
hypothalamus
Dopaminerge: substantia Noradrenerg: Locus 5HTerge: raphe Cortico-striatale-
Banen
nigra en tegmentum Coeruleus naar cortex, nucleus thalamische-corticale loop
thalamus, hippocampus,
cerebellum, etc.
Vesikel Acetylcholine
VMAT 2 VMAT 2 VMAT 2 VIAAT VGLUTS
transporters transporters
Ionotrope: AMPA, Ionotrope: nicotine
Ionotrope GABA a+c Kainaat, NMDA receptor
Receptoren g-proteïne: D1-5 GPCR’s: α + β GPCR’s: 5HT
Metabotrope: GABA b Metabotrope: Metabotrope: Muscarine
glutamaatreceptor I-III (M1-M5)
Heropname Noradrenaline Transporter Serotonine Transporter GAT
Dopaminetransporter Aminozuur Transporters X
transporters (NET) (SERT) Astrocyten en gliacellen
Acetylcholinesterase
Enzym
MAO + COMT MAO + COMT MAO GABA-T Glutamine synthetase Gliaal
metabolieten
butytylcholinesterase
