HESI PHARMACOLOGY (QUESTIONS AND ANSWERS) (2022-2023)
• A client who is receiving chemotherapy is prescribed ondansetron (Zofran). What side effect should the nurse include in
the teaching plan?
o Headache
• A young adult female is brought to the emergency room by family members who report that she ingested a large quantity
of acetaminophen (Tylenol). The nurse should prepare for which treatment to be implemented?
o Acetylcysteine (Mucomyst) 140 mg/kg
• A client receives a new prescription for pentazocine (talwin), a mixed opioid angonist-antagonist, after an opiod agonist is
discontinued. What is the advantage for the client when the new prescription is implemented?
o Respiratory depression is less
• What is the effect of beta-blocking agents when used for treament of glaucoma?
o Inhibiting aqueous humor production
• A client asks the nurse to explain the meaning of a narrow therapeutic index of a medication. What information should the
nurse use to answer the question?
o A small margin exists between safe and toxic plasma levels.
• The healthcare provider prescribes pyridostigmine bromide (Mestinon) tablets for a client with myasthenia gravis (MG).
What instruction should the nurse provide the client?
o Take the medication 30-45 minutes before eating
• Which drug of choice is indicated for acute ventricular dysrhythmias associated with myocardial infarction?
o Amiodarone
• A client calls the clinic and states that she forgot to take her oral contraceptives for the past two days. Which instruction is
best for the nurse to provide to this client?
o Take 2 pills a day for 2 days and use an alternate method of contraception for 7 days
• The healthcare provider discontinues prednisone, a glucocorticoid, for a client with chronic obstructive pulmonary disease.
What instruction should the nurse give the client about the regimen to follow?
o The does must be tapered over the course of 7-10 days
• An older client is taking warfarin sodium (coumadin) PO 2.5 mg twice a day. Which laboratory value should the nurse
identify as a therapeutic response of the medication?
o INR of 2 to 3
• A client receives a new prescription for an angiotensin-converting enzyme (ACE) inhibitor. What client history
contraindicates its use?
o Renal artery stenosis
• A female client receives a prescription for cefadroxil (duricef) for a urinary tract infection. The client informs the nurse that
she is currently taking oral contraceptives (OCP). What information is important for the nurse to share with the client?
o Use additional form of contraception until your menstrual cycle.
• Which findings should the nurse identify in an adult client with possible chronic salicylate intoxicaiton?
o Tinnitus and hearing loss
• To treat cystitis, a 14-day course treatment with cephalexin (Ceclor) is prescried for a client residing in a long-term care
facility. Which action is most important for the nurse to take prior to administering the first dose of this medication?
o Determine if the client has every had hypersensitivity reaction to penicillins
This study source was downloaded by 100000853187528 from CourseHero.com on 01-15-2023 05:52:30 GMT -06:00
https://www.coursehero.com/file/11192461/HESI-questions/
, HESI PHARMACOLOGY (QUESTIONS AND ANSWERS) (2022-2023)
• The nurse should instruct a client to avoid which product while taking carisoprodol (Soma) for muscle spasms?
o Alocoholic beverages
• A client who has been taking diuretic and ACE inhibitor for hypertension has a blood pressure of 160/90. Today a new
drug, carvediol (Coreg), is prescribed, and the client expresses concern about receiving so many different medications.
What action should the nurse implement?
o Explain the rationale for the administration of all three medications to the client
• A client receives a new prescription for ciproflaxin (Cipro), a synthetic quinolone. When teaching about this drug, which
information in the client’s history requires special emphasis by the nurse?
o Works twenty hours a week as a lifeguard at the local pool
• Which route should the nurse clarify with the healthcare provider prior to administering a drug with a high first-pass
effect?
o Oral
• A client with chronic kidney disease (CKD) and severe anemia refuses blood transfusions. The healthcare provider
prescribes epoetin alfa. Which action should the nurse explain to the client about the medication’s therapeutic response?
o Stimulates erythropoiesis in the bone marrow to increase circulating erythrocytes
• A client with chronic pancreatitis receives a new prescription for pancrelipase (Pancrease). Which incrtuction is most
important for the nurse to include in this clients teaching?
o Take the medication when comsuming food
• A resident of a long-term care facility is taking lithium carbonate (Eskalith) to treat bipolar disorder. Which instructions
should the nurse provide to this client’s caregivers?
o Report symptoms of hypothyroidism such as fatigue and constipation
• A client is admitted for atrial fibrillation, and the healthcare provider prescribes disopyramide (Norpace). After explaining
the action of this antidysrhythmic agent, which complaint should the nurse instruct the client to report?
o Daily weight gain of 2 pounds
• The nurse administers the initial dose of a fentanyl (Duragesic) transdermal patch to a client with chronic pain. When
monitoring the client an hour later, which assessment is most important for the nurse to obtain?
o Numeric pain scale
• A young adult female is brought to the emergency room by family members who report she ingested a large quantity of
acetaminophen (Tylenol). The nurse should prepare for which treatment to be implemented?
o Acetylcysteine (Mucomyst) 140 mg/kg
• The nurse receives a unit of blood from the blood bank for a postoperative client who is currently in the X-ray department.
What action should the nurse implement?
o Return the blood to the blood bank for refrigetration within 30 minutes
• A client beginning therapy with montelukast (Singulair) PO 10 mg once a day in the evening. The client asks the nurse,
When should I begin to feel better? How should the nurse respond?
o 30 minutes to 1 hour
• Which client requires the most immediate intervention by the nurse?
o A young adult who is reporting an anaphylactic response to an antibiotic
• The nurse is providing medication teaching for a client who has recently received a prescription for clozapine (Clozaril).
Which instruction should be included in this client’s teaching pan?
This study source was downloaded by 100000853187528 from CourseHero.com on 01-15-2023 05:52:30 GMT -06:00
https://www.coursehero.com/file/11192461/HESI-questions/
• A client who is receiving chemotherapy is prescribed ondansetron (Zofran). What side effect should the nurse include in
the teaching plan?
o Headache
• A young adult female is brought to the emergency room by family members who report that she ingested a large quantity
of acetaminophen (Tylenol). The nurse should prepare for which treatment to be implemented?
o Acetylcysteine (Mucomyst) 140 mg/kg
• A client receives a new prescription for pentazocine (talwin), a mixed opioid angonist-antagonist, after an opiod agonist is
discontinued. What is the advantage for the client when the new prescription is implemented?
o Respiratory depression is less
• What is the effect of beta-blocking agents when used for treament of glaucoma?
o Inhibiting aqueous humor production
• A client asks the nurse to explain the meaning of a narrow therapeutic index of a medication. What information should the
nurse use to answer the question?
o A small margin exists between safe and toxic plasma levels.
• The healthcare provider prescribes pyridostigmine bromide (Mestinon) tablets for a client with myasthenia gravis (MG).
What instruction should the nurse provide the client?
o Take the medication 30-45 minutes before eating
• Which drug of choice is indicated for acute ventricular dysrhythmias associated with myocardial infarction?
o Amiodarone
• A client calls the clinic and states that she forgot to take her oral contraceptives for the past two days. Which instruction is
best for the nurse to provide to this client?
o Take 2 pills a day for 2 days and use an alternate method of contraception for 7 days
• The healthcare provider discontinues prednisone, a glucocorticoid, for a client with chronic obstructive pulmonary disease.
What instruction should the nurse give the client about the regimen to follow?
o The does must be tapered over the course of 7-10 days
• An older client is taking warfarin sodium (coumadin) PO 2.5 mg twice a day. Which laboratory value should the nurse
identify as a therapeutic response of the medication?
o INR of 2 to 3
• A client receives a new prescription for an angiotensin-converting enzyme (ACE) inhibitor. What client history
contraindicates its use?
o Renal artery stenosis
• A female client receives a prescription for cefadroxil (duricef) for a urinary tract infection. The client informs the nurse that
she is currently taking oral contraceptives (OCP). What information is important for the nurse to share with the client?
o Use additional form of contraception until your menstrual cycle.
• Which findings should the nurse identify in an adult client with possible chronic salicylate intoxicaiton?
o Tinnitus and hearing loss
• To treat cystitis, a 14-day course treatment with cephalexin (Ceclor) is prescried for a client residing in a long-term care
facility. Which action is most important for the nurse to take prior to administering the first dose of this medication?
o Determine if the client has every had hypersensitivity reaction to penicillins
This study source was downloaded by 100000853187528 from CourseHero.com on 01-15-2023 05:52:30 GMT -06:00
https://www.coursehero.com/file/11192461/HESI-questions/
, HESI PHARMACOLOGY (QUESTIONS AND ANSWERS) (2022-2023)
• The nurse should instruct a client to avoid which product while taking carisoprodol (Soma) for muscle spasms?
o Alocoholic beverages
• A client who has been taking diuretic and ACE inhibitor for hypertension has a blood pressure of 160/90. Today a new
drug, carvediol (Coreg), is prescribed, and the client expresses concern about receiving so many different medications.
What action should the nurse implement?
o Explain the rationale for the administration of all three medications to the client
• A client receives a new prescription for ciproflaxin (Cipro), a synthetic quinolone. When teaching about this drug, which
information in the client’s history requires special emphasis by the nurse?
o Works twenty hours a week as a lifeguard at the local pool
• Which route should the nurse clarify with the healthcare provider prior to administering a drug with a high first-pass
effect?
o Oral
• A client with chronic kidney disease (CKD) and severe anemia refuses blood transfusions. The healthcare provider
prescribes epoetin alfa. Which action should the nurse explain to the client about the medication’s therapeutic response?
o Stimulates erythropoiesis in the bone marrow to increase circulating erythrocytes
• A client with chronic pancreatitis receives a new prescription for pancrelipase (Pancrease). Which incrtuction is most
important for the nurse to include in this clients teaching?
o Take the medication when comsuming food
• A resident of a long-term care facility is taking lithium carbonate (Eskalith) to treat bipolar disorder. Which instructions
should the nurse provide to this client’s caregivers?
o Report symptoms of hypothyroidism such as fatigue and constipation
• A client is admitted for atrial fibrillation, and the healthcare provider prescribes disopyramide (Norpace). After explaining
the action of this antidysrhythmic agent, which complaint should the nurse instruct the client to report?
o Daily weight gain of 2 pounds
• The nurse administers the initial dose of a fentanyl (Duragesic) transdermal patch to a client with chronic pain. When
monitoring the client an hour later, which assessment is most important for the nurse to obtain?
o Numeric pain scale
• A young adult female is brought to the emergency room by family members who report she ingested a large quantity of
acetaminophen (Tylenol). The nurse should prepare for which treatment to be implemented?
o Acetylcysteine (Mucomyst) 140 mg/kg
• The nurse receives a unit of blood from the blood bank for a postoperative client who is currently in the X-ray department.
What action should the nurse implement?
o Return the blood to the blood bank for refrigetration within 30 minutes
• A client beginning therapy with montelukast (Singulair) PO 10 mg once a day in the evening. The client asks the nurse,
When should I begin to feel better? How should the nurse respond?
o 30 minutes to 1 hour
• Which client requires the most immediate intervention by the nurse?
o A young adult who is reporting an anaphylactic response to an antibiotic
• The nurse is providing medication teaching for a client who has recently received a prescription for clozapine (Clozaril).
Which instruction should be included in this client’s teaching pan?
This study source was downloaded by 100000853187528 from CourseHero.com on 01-15-2023 05:52:30 GMT -06:00
https://www.coursehero.com/file/11192461/HESI-questions/
