TEST BANK
ABRAMS’
CLINICAL DRUG THERAPY
Rationales for Nursing Practice
12th Edition
Geralyn Frandsen
TEST BANK
,Abrams’ Clinical Drug Therapy Rationales for Nursing Practice 12th Edition Test Bank
Table of Contents:
SECTION 1 The Conceptual Framework of Pharmacology
Chapter 1 The Foundation of Pharmacology: Quality and Safety
Chapter 2 Basic Concepts and Processes
Chapter 3 Medication Administration and the Nursing Process of Drug Therapy
SECTION 2 Drug Therapy Throughout the Lifespan
Chapter 4 Pharmacology and the Care of Infants and Pediatric Patients Medication Administration in Pediatrics
Chapter 5 Pharmacology and the Care of Adults and Geriatric Patients
Chapter 6 Pharmacology and the Care of Pregnant or Lactating Woman
Chapter 7 Pharmacology and Women’s Health
Chapter 8 Pharmacology and Men’s Health
SECTION 3 Drugs Affecting the Hematopoietic and Immune Systems
Chapter 9 Drug Therapy for Coagulation Disorders
Chapter 10 Drug Therapy for Dyslipidemia
Chapter 11 Drug Therapy for Hematopoietic Disorders
Chapter 12 Drug Therapy: Immunizations
Chapter 13 Drug Therapy to Decrease Immunity
Chapter 14 Drug Therapy for the Treatment of Cancer
SECTION 4 Drugs Affecting Inflammation and Infection
Chapter 15 Inflammation, Infection, and the Use of Antimicrobial Agents
Chapter 16 Drug Therapy to Decrease Pain, Fever, and Inflammation
Chapter 17 Drug Therapy With Corticosteroids
Chapter 18 Drug Therapy With Beta-Lactam Antibacterial Agents
Chapter 19 Drug Therapy With Aminoglycosides and Fluoroquinolones
Chapter 20 Drug Therapy With Tetracyclines, Sulfonamides, and Urinary Antiseptics
Chapter 21 Drug Therapy With Macrolides and Miscellaneous Anti-infective Agents
Chapter 22 Drug Therapy for Tuberculosis and Mycobacterium avium Complex Disease
Chapter 23 Drug Therapy for Viral Infections
Chapter 24 Drug Therapy for Fungal Infections
Chapter 25 Drug Therapy for Parasitic Infections
SECTION 5 Drugs Affecting the Cardiovascular System
Chapter 26 Drug Therapy for Hypertension
Chapter 27 Drug Therapy for Dysrhythmias
Chapter 28 Drug Therapy for Coronary Heart Disease
Chapter 29 Drug Therapy for Shock and Hypotension
Chapter 30 Drug Therapy for Heart Failure
SECTION 6 Drugs Affecting the Respiratory System
Chapter 31 Drug Therapy for Nasal Congestion and Cough
Chapter 32 Drug Therapy to Decrease Histamine Effects and Allergic Response
Chapter 33 Drug Therapy for Asthma and Bronchoconstriction
SECTION 7 Drugs Affecting the Renal and Digestive Systems
Chapter 34 Drug Therapy for Fluid Volume Excess
Chapter 35 Nutritional Support Products, Vitamins, and Mineral Supplements
Chapter 36 Drug Therapy for Weight Management
Chapter 37 Drug Therapy for Peptic Ulcer Disease and Hyperacidity
Chapter 38 Drug Therapy for Nausea and Vomiting
,Chapter 39 Drug Therapy for Constipation and Elimination Problems
Chapter 40 Drug Therapy for Diarrhea
SECTION 8 Drugs Affecting the Endocrine System
Chapter 41 Drug Therapy for Diabetes Mellitus
Chapter 42 Drug Therapy for Hyperthyroidism and Hypothyroidism
Chapter 43 Drug Therapy for Pituitary and Hypothalamic Dysfunction
Chapter 44 Drug Therapy to Regulate Calcium and Bone Metabolism
Chapter 45 Drug Therapy for Addison’s Disease and Cushing’s Disease
SECTION 9 Drugs Affecting the Autonomic and Central Nervous System
Chapter 46 Physiology of the Autonomic and Central Nervous Systems and Indications for the Use of Drug
Therapy
Chapter 47 Drug Therapy for Myasthenia Gravis, Alzheimer’s Disease, and Urinary Retention
Chapter 48 Drug Therapy for Parkinson’s Disease, Urinary Spasticity, and Disorders Requiring
Anticholinergic Drug Therapy
Chapter 49 Drug Therapy With Opioids
Chapter 50 Drug Therapy With Local Anesthetics
Chapter 51 Drug Therapy With General Anesthetics
Chapter 52 Drug Therapy for Migraines and Other Headaches
Chapter 53 Drug Therapy for Seizure Disorders and Spasticity
Chapter 54 Drug Therapy for Anxiety and Insomnia
Chapter 55 Drug Therapy for Depression and Mood Stabilization
Chapter 56 Drug Therapy for Psychotic Disorders
Chapter 57 Drug Therapy for Attention Deficit Hyperactivity Disorder and Narcolepsy
Chapter 58 Drug Therapy for Substance Abuse Disorders
SECTION 10 Drugs Affecting the Eye, Ear, and Skin
Chapter 59 Drug Therapy for Disorders of the Eye
Chapter 60 Drug Therapy for Disorders of the Ear
Chapter 61 Drug Therapy for Disorders of the Skin
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
Abrams' Clinical Drug Therapy: Rationales for Nursing Practice 12th Edition
Test Bank
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated
through the bloodstream to their sites of action in various body tissues, and eventually
eliminated from the body. Curative agents are given to cure a disease process. In this
case, paroxetine hydrochloride will control the symptoms but not cure the disorder.
Drugs with local effects, such as sunscreen and local anesthetics, act mainly at the site of
application. Paroxetine hydrochloride is not administered parenterally. Parenteral agents
are administered subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been chemically modified. What is another name for this type of
medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic drugs are more standardized in
their chemical characteristics, more consistent in their effects, and less likely to produce
allergic reactions. Biotechnology drugs involve manipulating DNA and RNA and
recombining genes into hybrid molecules that can be inserted into living organisms.
Prototype drugs are the first drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
, A. Central nervous system depressant
B. Central nervous system stimulant
C. Anti-inflammatory
D. Antihypertensive
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems,
their therapeutic uses, and their chemical characteristics. Morphine is classified as a
central nervous system depressant and will produce this effect in the client. A central
nervous system stimulant increases attention and raises mood. An anti-inflammatory
agent decreases inflammation at the site of tissue or joint inflammation. An
antihypertensive agent reduces blood pressure.
PTS: 1 REF: p. 3, Drug Classifications and Prototypes
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to
which drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic name often indicates the drug group (e.g., drugs with generic
names ending in “cillin” are penicillins). Selective serotonin reuptake inhibitors are
medications that have antidepressant effects; SSRI is a broad classification, not a generic
name. Diuretics are medications that increase urine output; diuretic is a broad
classification, not a generic name. ACE inhibitor is the broad classification for the
angiotensin receptor blockers, not the generic name.
PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration
ANS: D
, Rationale: The Food and Drug Administration approves drugs for over-the-counter
availability, including the transfer of drugs from prescription to OTC status, and may
require clinical trials to determine the safety and effectiveness of OTC use. The Public
Health Service is regulated by the state to maintain the health of individual citizens of
the state. The Federal Trade Commission regulates imports and exports throughout the
nation. The Occupational Safety and Health Administration regulates safety within the
workplace.
PTS: 1 REF: p. 4, Prescription and Nonprescription Drugs
OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the
manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened
FDA powers and responsibilities, giving the FDA control over drug safety. The Harrison
Narcotic Act restricted the importation, manufacture, sale, and use of opium, cocaine,
marijuana, and other drugs that the act defined as narcotics. The Sherley Amendment of
1912 prohibited fraudulent claims of drug effectiveness.
PTS: 1 REF: p. 4, Prescription and Nonprescription Drugs
OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nurse is responsible for maintaining an accurate count and record of the controlled
substances on the nursing division. This nursing action is regulated by which U.S. law or
agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
ANS: C
ABRAMS’
CLINICAL DRUG THERAPY
Rationales for Nursing Practice
12th Edition
Geralyn Frandsen
TEST BANK
,Abrams’ Clinical Drug Therapy Rationales for Nursing Practice 12th Edition Test Bank
Table of Contents:
SECTION 1 The Conceptual Framework of Pharmacology
Chapter 1 The Foundation of Pharmacology: Quality and Safety
Chapter 2 Basic Concepts and Processes
Chapter 3 Medication Administration and the Nursing Process of Drug Therapy
SECTION 2 Drug Therapy Throughout the Lifespan
Chapter 4 Pharmacology and the Care of Infants and Pediatric Patients Medication Administration in Pediatrics
Chapter 5 Pharmacology and the Care of Adults and Geriatric Patients
Chapter 6 Pharmacology and the Care of Pregnant or Lactating Woman
Chapter 7 Pharmacology and Women’s Health
Chapter 8 Pharmacology and Men’s Health
SECTION 3 Drugs Affecting the Hematopoietic and Immune Systems
Chapter 9 Drug Therapy for Coagulation Disorders
Chapter 10 Drug Therapy for Dyslipidemia
Chapter 11 Drug Therapy for Hematopoietic Disorders
Chapter 12 Drug Therapy: Immunizations
Chapter 13 Drug Therapy to Decrease Immunity
Chapter 14 Drug Therapy for the Treatment of Cancer
SECTION 4 Drugs Affecting Inflammation and Infection
Chapter 15 Inflammation, Infection, and the Use of Antimicrobial Agents
Chapter 16 Drug Therapy to Decrease Pain, Fever, and Inflammation
Chapter 17 Drug Therapy With Corticosteroids
Chapter 18 Drug Therapy With Beta-Lactam Antibacterial Agents
Chapter 19 Drug Therapy With Aminoglycosides and Fluoroquinolones
Chapter 20 Drug Therapy With Tetracyclines, Sulfonamides, and Urinary Antiseptics
Chapter 21 Drug Therapy With Macrolides and Miscellaneous Anti-infective Agents
Chapter 22 Drug Therapy for Tuberculosis and Mycobacterium avium Complex Disease
Chapter 23 Drug Therapy for Viral Infections
Chapter 24 Drug Therapy for Fungal Infections
Chapter 25 Drug Therapy for Parasitic Infections
SECTION 5 Drugs Affecting the Cardiovascular System
Chapter 26 Drug Therapy for Hypertension
Chapter 27 Drug Therapy for Dysrhythmias
Chapter 28 Drug Therapy for Coronary Heart Disease
Chapter 29 Drug Therapy for Shock and Hypotension
Chapter 30 Drug Therapy for Heart Failure
SECTION 6 Drugs Affecting the Respiratory System
Chapter 31 Drug Therapy for Nasal Congestion and Cough
Chapter 32 Drug Therapy to Decrease Histamine Effects and Allergic Response
Chapter 33 Drug Therapy for Asthma and Bronchoconstriction
SECTION 7 Drugs Affecting the Renal and Digestive Systems
Chapter 34 Drug Therapy for Fluid Volume Excess
Chapter 35 Nutritional Support Products, Vitamins, and Mineral Supplements
Chapter 36 Drug Therapy for Weight Management
Chapter 37 Drug Therapy for Peptic Ulcer Disease and Hyperacidity
Chapter 38 Drug Therapy for Nausea and Vomiting
,Chapter 39 Drug Therapy for Constipation and Elimination Problems
Chapter 40 Drug Therapy for Diarrhea
SECTION 8 Drugs Affecting the Endocrine System
Chapter 41 Drug Therapy for Diabetes Mellitus
Chapter 42 Drug Therapy for Hyperthyroidism and Hypothyroidism
Chapter 43 Drug Therapy for Pituitary and Hypothalamic Dysfunction
Chapter 44 Drug Therapy to Regulate Calcium and Bone Metabolism
Chapter 45 Drug Therapy for Addison’s Disease and Cushing’s Disease
SECTION 9 Drugs Affecting the Autonomic and Central Nervous System
Chapter 46 Physiology of the Autonomic and Central Nervous Systems and Indications for the Use of Drug
Therapy
Chapter 47 Drug Therapy for Myasthenia Gravis, Alzheimer’s Disease, and Urinary Retention
Chapter 48 Drug Therapy for Parkinson’s Disease, Urinary Spasticity, and Disorders Requiring
Anticholinergic Drug Therapy
Chapter 49 Drug Therapy With Opioids
Chapter 50 Drug Therapy With Local Anesthetics
Chapter 51 Drug Therapy With General Anesthetics
Chapter 52 Drug Therapy for Migraines and Other Headaches
Chapter 53 Drug Therapy for Seizure Disorders and Spasticity
Chapter 54 Drug Therapy for Anxiety and Insomnia
Chapter 55 Drug Therapy for Depression and Mood Stabilization
Chapter 56 Drug Therapy for Psychotic Disorders
Chapter 57 Drug Therapy for Attention Deficit Hyperactivity Disorder and Narcolepsy
Chapter 58 Drug Therapy for Substance Abuse Disorders
SECTION 10 Drugs Affecting the Eye, Ear, and Skin
Chapter 59 Drug Therapy for Disorders of the Eye
Chapter 60 Drug Therapy for Disorders of the Ear
Chapter 61 Drug Therapy for Disorders of the Skin
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
Abrams' Clinical Drug Therapy: Rationales for Nursing Practice 12th Edition
Test Bank
1. A woman diagnosed with obsessive–compulsive disorder has been prescribed oral
paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated
through the bloodstream to their sites of action in various body tissues, and eventually
eliminated from the body. Curative agents are given to cure a disease process. In this
case, paroxetine hydrochloride will control the symptoms but not cure the disorder.
Drugs with local effects, such as sunscreen and local anesthetics, act mainly at the site of
application. Paroxetine hydrochloride is not administered parenterally. Parenteral agents
are administered subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been chemically modified. What is another name for this type of
medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic drugs are more standardized in
their chemical characteristics, more consistent in their effects, and less likely to produce
allergic reactions. Biotechnology drugs involve manipulating DNA and RNA and
recombining genes into hybrid molecules that can be inserted into living organisms.
Prototype drugs are the first drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
, A. Central nervous system depressant
B. Central nervous system stimulant
C. Anti-inflammatory
D. Antihypertensive
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems,
their therapeutic uses, and their chemical characteristics. Morphine is classified as a
central nervous system depressant and will produce this effect in the client. A central
nervous system stimulant increases attention and raises mood. An anti-inflammatory
agent decreases inflammation at the site of tissue or joint inflammation. An
antihypertensive agent reduces blood pressure.
PTS: 1 REF: p. 3, Drug Classifications and Prototypes
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to
which drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic name often indicates the drug group (e.g., drugs with generic
names ending in “cillin” are penicillins). Selective serotonin reuptake inhibitors are
medications that have antidepressant effects; SSRI is a broad classification, not a generic
name. Diuretics are medications that increase urine output; diuretic is a broad
classification, not a generic name. ACE inhibitor is the broad classification for the
angiotensin receptor blockers, not the generic name.
PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration
ANS: D
, Rationale: The Food and Drug Administration approves drugs for over-the-counter
availability, including the transfer of drugs from prescription to OTC status, and may
require clinical trials to determine the safety and effectiveness of OTC use. The Public
Health Service is regulated by the state to maintain the health of individual citizens of
the state. The Federal Trade Commission regulates imports and exports throughout the
nation. The Occupational Safety and Health Administration regulates safety within the
workplace.
PTS: 1 REF: p. 4, Prescription and Nonprescription Drugs
OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the
manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened
FDA powers and responsibilities, giving the FDA control over drug safety. The Harrison
Narcotic Act restricted the importation, manufacture, sale, and use of opium, cocaine,
marijuana, and other drugs that the act defined as narcotics. The Sherley Amendment of
1912 prohibited fraudulent claims of drug effectiveness.
PTS: 1 REF: p. 4, Prescription and Nonprescription Drugs
OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nurse is responsible for maintaining an accurate count and record of the controlled
substances on the nursing division. This nursing action is regulated by which U.S. law or
agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
ANS: C
