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BSN HESI 315 Pharmacology Practice Exam – New 2026–2027 Update, Questions and Answers (Grade A)

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This document contains practice-style BSN HESI 315 Pharmacology exam questions with verified correct answers based on the 2026–2027 exam update. It focuses on medication safety, pharmacologic interventions, adverse effects, and clinical judgment commonly tested on HESI pharmacology exams.

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2025/2026
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BSN HESI 315 Pharmacology Exam v1
(New 2026/ 2027 Update) over 200
Questions and Answers |100 out of 100|
Grade A- Nightingale


What hormone stimulates the release of the follicle-stimulating hormone (FSH) from both male
and female glands?

A)Growth hormone-releasing hormone (GHRH)
B)Thyrotropin-releasing hormone (TRH)
C)Gonadotropin-releasing hormone (GnRH)

D)Prolactin-releasing hormone (PRH)

c



The male and female glands respond to luteinizing hormone (LH) and FSH, which are released
from the anterior pituitary in response to stimulation from GnRH that is released from the
hypothalamus. GHRH stimulates the release of the growth hormone, which targets cell growth.
TRH stimulates the thyroid-stimulating hormone, which targets the thyroid gland. PRH
stimulates the release of prolactin, which is necessary for milk production.




A nurse is providing patient education to a patient as part of her work in a fertility clinic. The
nurse explains possible reasons for infertility. When explaining how the ovaries are involved in
conception, what will the nurse stress?


A)Ova quickly degenerate and most are absorbed in the body before the age of 12.

B)The ovaries at birth contain all of the ova that a woman will have.

C)Ova aggregate, causing millions to be contained in a storage site called a follicle.
D)Follicles produce only estrogen; the uterus produces progesterone.

b

, BSN HESI 315 Pharmacology Exam v1
(New 2026/ 2027 Update) over 200
Questions and Answers |100 out of 100|
Grade A- Nightingale
It would be important to explain that the woman's ova do not increase or decrease from birth to
childbearing years. The nurse will stress that all the ova that a woman will have will be present at
birth. The patient should understand that if she does not ovulate 1 month or for several months, it
is not because she has done something to her body to cause this. Ova slowly degenerate over a
lifetime or they are released once a month until menopause is complete. Each ovum is contained
in a storage site called a follicle, which produces the female sex hormones, estrogen and
progesterone.




The nursing instructor is discussing the physiology of pregnancy with her clinical group. What
hormone, produced during pregnancy, would the instructor tell the students helps to maintain the
pregnancy until birth of the fetus?

A)High levels of estrogen only

B)High levels of estrogen, low levels of progesterone

C)Low levels of estrogen, high levels of progesterone
D)High levels of estrogen and progesterone

D

Feedback:

In a pregnant woman, both estrogen and progesterone hormones have specific functions. High
levels of both hormones are needed for the maintenance of pregnancy.




The nursing instructor is talking with her class of students about the female reproductive system.
A student is trying to understand the role of progesterone in the body. What nonreproductive
affect does progesterone have on the body?
A)Decreased body temperature B)Decreased appetite C)Anti-insulinD)Increased uterine motility

, BSN HESI 315 Pharmacology Exam v1
(New 2026/ 2027 Update) over 200
Questions and Answers |100 out of 100|
Grade A- Nightingale
C

Feedback:

Progesterone has an anti-insulin effect to generate a higher blood glucose concentration to allow
for rapid diffusion of glucose to the developing embryo. Body temperature and appetite are
increased by progesterone. Uterine motility is decreased to provide increased chance that
implantation can occur.




What hormone causes ovulation to occur? A)Adrenocorticotropic hormone (ACTH)

B)Luteinizing hormone (LH)

C)Prolactin
D)Follicle-stimulating hormone (FSH)

B

Feedback:

When the circulating estrogen level rises high enough, it stimulates a massive release of LH from
the anterior pituitary causing one of the developing follicles to burst and release the ovum with
its stored hormones into the system. ACTH targets the adrenal corticosteroid hormone, which
helps prepare the body for the "fight or flight" response. Prolactin is responsible for milk
production and FSH in combination with LH stimulate follicles on the outer surface of the uterus
to grow and develop and also stimulates the release of estrogen and progesterone.




A 16-year-old girl comes to the clinic complaining of severe menstrual cramps. The girl is
concerned about the pain and worried that "something is wrong." The nurse explains to the
patient that she has cramping during her menstrual period because of what?


A)An increase in the levels of estrogen and progesterone, which cause uterine contractions

, BSN HESI 315 Pharmacology Exam v1
(New 2026/ 2027 Update) over 200
Questions and Answers |100 out of 100|
Grade A- Nightingale
B)Low levels of plasminogen in the uterus that cause the shedding of the lining of the uterus

C)Prostaglandins in the uterus, which stimulate uterine contractions to clamp off vessels as the
lining of her uterus sheds

D)An increase in progesterone and a decrease of estrogen cause the lining of the uterus to slough
away

C Feedback:

Prostaglandins in the uterus stimulate uterine contractions to clamp off vessels in the lining of
the uterus, which is the cause of the cramping. The decrease of estrogen and progesterone after
the involution of the corpus luteum triggers the release of follicle- stimulating hormone (FSH)
and luteinizing hormone (LH). The decreased levels of FSH and LH cause the inner lining of the
uterus to slough off because the vascular system is no longer being stimulated. High, not low,
levels of plasminogen in the uterus prevent clotting of the lining as the vessels shear off.




What drug would the nurse expect to administer if beta-specific adrenergic agonist effects are
desired to prevent bronchospasm during anesthesia?
A)Dobutamine (Dobutrex) B)Ephedrine (generic) C)Isoproterenol (Isuprel) D)Phenylephrine
(Neo-Synephrine)
C

Isoproterenol is a beta-specific adrenergic agonist used to prevent bronchospasm during
anesthesia. Phenylephrine is an alpha-specific adrenergic agonist. Both dobutamine and
ephedrine are alpha- and beta-adrenergic agonists.




The nurse is preparing discharge teaching for four patients. Which patient should be advised by
the nurse that over-the-counter cold and allergy preparations contain phenylephrine and should
be avoided?

A)A 47-year-old woman with hypertensionB)A 52-year-old man with adult onset diabetes
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