University of Brighton (UOB) • Rhiannonmoody

Notes on dementia for an innovations in bioscience research module taught on the third year of a biomedical science degree. Notes cover; ageing, theories of ageing, werner syndrome, Hutchison-Guilford syndrome, senescence, senescence associated secretory phenotype, telomere dependent and independent senescence, laboratory investigation of senescence, senolytics, cerebral amyloid angiopathy, the link between dementia and urinary tract infections, and the link between dementia and hyperammonemia.

Notes on the topic of biomaterials for an innovations in biomedical science degree taught on the third of a biomedical science degree course. These notes cover artificial kidney, artificial liver, and opthalamic biomaterials, with relevant research papers discussed for each topic.

Notes covering a clinical immunology module taught on the third year of a biomedical science degree. Topics covered include; vaccination, immune responses to infectious disease, immune responses to cancer, transfusion science, hypersensitivities, transplantation, tolerance, and autoimmunity.

Notes on the topic of autoimmunity for a clinical immunology module taught on the third year of a biomedical science degree course. These notes cover the epidemiology, pathogenesis, autoimmune component, symptoms, diagnosis, and treatment of numerous autoimmune diseases including; Hashimoto's thyroiditis, type 1 diabetes, Myasthenia Gravis, systemic lupus erythematosus, Multiple sclerosis, and rheumatoid arthritis. Additional topics covered include; the role of genetic factors in autoimmunity s...

Notes of the topic of tolerance in the context of the immune system for a clinical immunology module taught on the third year of a biomedical science degree course. Topics covered include; antigen sequestration, central tolerance, peripheral tolerance, and immune cells in the periphery that inhibit anti-self responses.

Notes on the calcification on the grwoth plate and vascular pathologic calcification for a cellular pathology and special topics in pathobiology module taught on the third year of a biomedical science degree course. These notes explore the possibility that calcification in the growth plate may be a model for pathological calcification in the vasculature, the similarities in mechanisms of calcification between the growth plate and the vasculature are discussed including the role of transcription ...

Notes covering a cellular pathology module taught on the third year of a biomedical science degree course. Topics covered include; rheumatoid arthritis, inflammation and cancer, the tumour microenvironment, oxidative stress and kidney injury, medical imaging, nuclear medicine, molecular diagnostics, oxidative stress and diabetic neuropathy, pathological calcification, and the growth plate calcification and vascular calcification.

Notes on the topic of pathological calcification for a cellular pathology taught on the third year of a biomedical science degree. Notes cover; bone physiology, calcium homeostasis, the action of parathyroid hormone, secondary hyperparathyroidism, techniques to prepare bone tissue sections, the basics of pathological calcification, dystrophic calcification, and metastatic calcification.

Notes covering the topic of diabetic neuropathy, for a cellular pathology module taught on the third year of a biomedical science degree course. Notes cover; the role and vulnerability of the dorsal root ganglia in diabetic neuropathy, the clinical presentation of diabetic neuropathy, and the pathophysiology of diabetic neuropathy with a focus on the role of the polyol pathway, AGE products and the mitochondria.

Notes covering the whole of a clinical microbiology module taught on the third year of a biomedical science degree course. Topics covered included; urinary tract infections, antibiotic resistance, antimicrobial agents, blood bourne infections, infections in compromised hosts, microorganism toxins, epidemiology, vaccine program efficacy, and tuberculosis.