NR 565 / NR565 Advanced Pharmacology Exam Review | Weeks 5-8 Covered| Complete Guide with Questions and Verified Answers (2023/ 2024)

Final Exam: NR 565 / NR565 Advanced Pharmacology Exam Review | Weeks 5-8 Covered| Complete Guide with Questions and Verified Answers (2023/ 2024) Q: DTaP or Tdap o Who should receive the Tdap vaccine? Answer: Teens and adults after receiving full DTaP course during childhood Q: Vaccine Contraindications o True contraindication for DTaP or Tdap vaccine. Answer: Moderate to severe febrile illness Hx of post-vaccination anaphylactic reaction (immediate) or encephalopathy within 7 days Caution: if prior vaccination produced a shock-like state, fever over 105 within 48 hours, persistent inconsolable crying within 48 hours lasting for 3 hours, or seizures within 3 days. Q: Vaccine Contraindications o Varicella Answer: Pregnancy, certain cancers, hypersensitivity to neomycin or gelatin, immunocompromised. Children should avoid salicylates for 6 weeks after Q: Vaccine Contraindications o Hepatitis B virus (HBV) vaccine Answer: Prior anaphylactic reaction to vaccine or baker's yeast Q: Examples of vaccine types o Attenuated Answer: MMR, varicella, rotavirus, influenza (intranasal) Q: Examples of vaccine types o Live virus Answer: MMR, varicella, rotavirus, influenza Q: Examples of vaccine types o Toxoid Answer: Dtap Q: Examples of vaccine types o Inactive viral antigen Answer: Polio, Hep A and B, influenzas (inactivated) Q: Types of immunity o What are they and how is each one achieved? Answer: Herd/community - when a large group of people is immune Active - when responding to either real infection or vaccination Passive - transmitted from mother to baby or via antibodies Natural immunity - nonspecific, such as physical barriers, NK cells, etc. Acquired immunity - specific after exposure to a foreign substance, produce anti- gens Cell-mediated immunity - immune response where targets are attacked directly by cells Humoral immunity - immunity response medicated by antibodies Q: Definition of vaccine Answer: o a preparation containing whole or fractionated mi- croorganisms. Administration causes the recipient's immune system to manufacture antibodies directed against the microbe from which the vaccine was made Q: Post exposure prophylaxis for suspected rabies bite Answer: o 4 doses of vaccine - 1ml IM on days 0,3,7,14, with RIG (rabies immune globulin) given on day 0.Those who have previously been vaccinated, 2 doses are given on days 0 and 3, no RIG Q: Patient teaching and assessments for post vaccine side effects Answer: o Vaccine Information Statement (VIS) on administered vaccines, Administer Tylenol to the patient before discharge, discuss reactions for administered vaccines, provide a schedule for upcoming vaccine doses, have patient wait 15 minutes before dis- charge Q: Who can receive attenuated influenza vaccine (FluMist)? Answer: o Healthy non-pregnant patients ages 2 49, with no hx of previous reactions to this vaccine, not immunocompromised or caring for someone who is. Contraindicated in kids with asthma or kids receiving meds with salicylates. Q: Pantoprazole -common doses (calculations to figure quantity) -directions for use -indication Answer: o Common Doses: 20 and 40mg delayed-release tablets and 40mg enteric-coated granules o Directions for use: Monitor for pain relief and eradication of H. pylori infection. When used long term, there is an increase for osteoporosis and fractures = maintain an adequate intake of calcium and vitamin D, and inform patients about symptoms of hypomagnesemia, including muscle cramps, palpitations, and tremors o Indication: Gastric and duodenal ulcers, as well as GERD Q: Metronidazole -common doses (calculations to figure quantity) -directions for use -indication Answer: o Common Doses: 500mg three times a day for 10-14 days o Directions for use: The most common side effect is nausea and headache. A disulfiram-like reaction can occur if used with alcohol and it should also not be taken during pregnancy. o Indication: H. pylori treatment (very effective against sensitive strains of H. pylori Q: Ondansetron -common doses (calculations to figure quantity) -directions for use -indication Answer: o Common Doses: